Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Yalda S. Mostofi"'
Autor:
Anna Aparicio, Sarah Hudson, Warren Wade, Hua Wang, Wesley J. Dwight, Yalda S. Mostofi, Wendy Eccles, Jenny Wen, Mehrak Kiankarimi, Kathleen Gogas, Beth A. Fleck, Marc J. Genicot
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 18:4491-4494
The synthesis and SAR of a series of chiral heterocyclic ring-constrained norepinephrine reuptake inhibitors are described. The best compounds compare favorably with atomoxetine in potency (IC(50)s10 nM), selectivity against the other monoamine trans
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7dd576616be21f774ec8d52ceb4b4a7d
https://doi.org/10.1016/j.bmcl.2008.07.049
https://doi.org/10.1016/j.bmcl.2008.07.049
Autor:
Sarah Hudson, Mehrak Kiankarimi, Wesley J. Dwight, Warren Wade, Kathleen Gogas, Yalda S. Mostofi, Beth A. Fleck, Wendy Eccles, Marc J. Genicot
Publikováno v:
Bioorganicmedicinal chemistry letters. 18(16)
The design, synthesis and SAR of a series of heterocyclic ring-constrained norepinephrine reuptake inhibitors are described. As racemates, the best compounds compare favorably with atomoxetine (IC(50)'s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::98dd54c253e9b6994fbfdfc72c6e6c31
https://pubmed.ncbi.nlm.nih.gov/18667309
https://pubmed.ncbi.nlm.nih.gov/18667309