Zobrazeno 1 - 10 of 22 pro vyhledávání: '"Yalda Ashraf-Kharaz"'
1
Akademický článek
Equine synovial fluid small non-coding RNA signatures in early osteoarthritis
Autor: Catarina Castanheira, Panagiotis Balaskas, Charlotte Falls, Yalda Ashraf-Kharaz, Peter Clegg, Kim Burke, Yongxiang Fang, Philip Dyer, Tim J. M. Welting, Mandy J. Peffers
Publikováno v: BMC Veterinary Research, Vol 17, Iss 1, Pp 1-12 (2021)
Abstract Background Osteoarthritis remains one of the greatest causes of morbidity and mortality in the equine population. The inability to detect pre-clinical changes in osteoarthritis has been a significant impediment to the development of effectiv
Externí odkaz: https://doaj.org/article/42deb3c221b0429a837b62a64e001690
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2
Akademický článek
Postnatal mechanical loading drives adaptation of tissues primarily through modulation of the non-collagenous matrix
Autor: Danae E Zamboulis, Chavaunne T Thorpe, Yalda Ashraf Kharaz, Helen L Birch, Hazel RC Screen, Peter D Clegg
Publikováno v: eLife, Vol 9 (2020)
Mature connective tissues demonstrate highly specialised properties, remarkably adapted to meet their functional requirements. Tissue adaptation to environmental cues can occur throughout life and poor adaptation commonly results in injury. However,
Externí odkaz: https://doaj.org/article/f6c5f7b0a8534af78bbc9c4b1a971574
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3
Akademický článek
Donor age affects proteome composition of tenocyte-derived engineered tendon
Autor: Agnieszka J. Turlo, Yalda Ashraf Kharaz, Peter D. Clegg, James Anderson, Mandy J. Peffers
Publikováno v: BMC Biotechnology, Vol 18, Iss 1, Pp 1-11 (2018)
Abstract Background The concept of tissue engineering is to deliver to the injury site biological scaffolds carrying functional cells that will enhance healing response. The preferred cell source is autologous in order to reduce immune response in th
Externí odkaz: https://doaj.org/article/597075f43ef041d9af43dd0539056cbc
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5
Age-related changes in microRNAs expression in cruciate ligaments of wild-stock house mice
Autor: Anne McArdle, Jane L. Hurst, Eithne Comerford, Gareth A. Nye, Katarzyna Goljanek Whysall, Yalda Ashraf Kharaz
Publikováno v: Physiological reports
AimCruciate ligaments (CLs) of the knee joint are commonly injured following trauma or ageing. MicroRNAs (miRs) are potential therapeutic targets in musculoskeletal disorders. This study aimed to 1) identify if wild-stock house (WSH) mice are an appr
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c90fc41e9d0dc5e655b55a5f571d05c
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6
Postnatal mechanical loading drives adaptation of tissues primarily through modulation of the non-collagenous matrix
Autor: Helen L. Birch, Peter D. Clegg, Hazel R. C. Screen, Yalda Ashraf Kharaz, Chavaunne T. Thorpe, Danae E Zamboulis
Publikováno v: eLife
ELIFE
eLife, Vol 9 (2020)
Mature connective tissues demonstrate highly specialised properties, remarkably adapted to meet their functional requirements. Tissue adaptation to environmental cues can occur throughout life and poor adaptation commonly results in injury. However,
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20056de421db2cff0597f1c14916ebed
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8
Small Non-Coding RNAome of Ageing Chondrocytes
Autor: Mandy J. Peffers, Xuan Liu, Philip Dyer, Yalda Ashraf Kharaz, Jonathan A Green, Tariq M. Haqqi, Yongxiang Fang, Panagiotis Balaskas, Tim J. M. Welting
Publikováno v: International Journal of Molecular Sciences, Vol 21, Iss 5675, p 5675 (2020)
International Journal of Molecular Sciences
Volume 21
Issue 16
International Journal of Molecular Sciences, 21(16):5675. Multidisciplinary Digital Publishing Institute (MDPI)
BackgroundAgeing is one of the leading risk factors predisposing cartilage to musculoskeletal diseases, including osteoarthritis. Cumulative evidence suggests that small non-coding RNAs play a role in cartilage-related pathological changes. However,
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57313df151adf2552a365d5330be2b2d
https://www.mdpi.com/1422-0067/21/16/5675
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9
Multiomics analysis of the mdx/mTR mouse model of Duchenne muscular dystrophy
Autor: Dylan C. Sarver, Christopher L. Mendias, Justin T Dzierzawski, Eithne Comerford, Brian McDonagh, Yalda Ashraf Kharaz, Alex N Piacentini, Douglas W. Van Pelt, Nathaniel P Disser, Logan R Eckhardt
Publikováno v: Connective Tissue Research
BioRxiv
Purpose/Aim Duchenne muscular dystrophy (DMD) is a progressive neuromuscular disease characterized by extensive muscle weakness. Patients with DMD lack a functional dystrophin protein, which transmits force and organizes the cytoskeleton of skeletal
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::057e937536af9be89c300e8024388535
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10
Small RNA signatures of the anterior cruciate ligament from patients with knee joint osteoarthritis
Autor: Mandy J. Peffers, Tim J. M. Welting, Eithne Comerford, Yalda Ashraf Kharaz, Yongxiang Fang
The anterior cruciate ligaments are susceptible to degeneration, resulting in pain, reduced mobility and development of the degenerative joint disease osteoarthritis. There is currently a paucity of knowledge on how anterior cruciate ligament degener
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc88cc77c497622d4867d68ecdf1f03f
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