Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Yalcin Cetin"'
Publikováno v:
Histochemistry and Cell Biology
Plasma cells (PCs) in human palatine tonsils are predominantly located in the germinal centres (GCs), in the subepithelial space and near the deep connective tissue septa surrounding each crypt. We analysed the location, phenotype, and proliferation
Autor:
Karen Schwabe, Yalcin Cetin
Publikováno v:
Histochemistry and Cell Biology. 137:589-597
Guanylin, a bioactive intestinal peptide, is involved in the cystic fibrosis transmembrane conductance (CFTR)-regulated electrolyte/water secretion in various epithelia. In the present work we report on the expression and cellular localization of gua
Autor:
Hasan Kulaksiz, Helmut Friess, Nathalia A. Giese, Markus W. Buechler, Oliver Kloeters, Yalcin Cetin
Publikováno v:
Scandinavian Journal of Gastroenterology. 43:447-455
The peptide hormones guanylin and uroguanylin and their receptor, guanylate cyclase C (GC-C), are expressed in pancreatic duct cells. In colon cancer, guanylin peptides are shown to exert strong anti-tumor activity through the GC-C pathway. The objec
Autor:
Sebastian Bachmann, Hasan Kulaksiz, Yalcin Cetin, A Janetzko, Daniel Rost, Sven G. Gehrke, Wolfgang Stremmel, Franziska Theilig
Publikováno v:
Journal of Endocrinology. 184:361-370
It is generally accepted that iron homeostasis is mainly controlled in the gastrointestinal tract by absorption of dietary iron. However, recent studies have shown that the kidneys are also involved in iron metabolism. Since the iron-regulatory and a
Publikováno v:
The American Journal of Pathology. 161:655-664
Cystic fibrosis transmembrane conductance regulator (CFTR)-mediated secretion of an electrolyte-rich fluid is a major but incompletely understood function of the salivary glands. We provide molecular evidence that guanylin, a bioactive intestinal pep
Publikováno v:
Proceedings of the National Academy of Sciences. 99:6796-6801
The Clara cells are nonciliated, nonmucous, secretory cells containing characteristic peptidergic granules; they constitute up to 80% of the epithelial cell population of the distal airways. Despite this exposed histotopology and abundance within the
Publikováno v:
Gut. 50:52-60
Background and aims: Recently, novel somatostatin receptor (sstr) subtype specific ligand analogues have been developed for medical treatment of neuroendocrine tumours expressing different sstrs (sstr1–5). At present, individual expression patterns
Publikováno v:
Cell and Tissue Research. 303:337-343
Na+/H+ exchangers (NHEs) are vital transmembrane transport proteins mediating the electroneutral exchange of Na+ and H+ ions in mammalian cells. In the epithelium of the lower intestine, the isoform NHE-3 is apparently involved in Na+ absorption; how
Autor:
Gabriele Zeck-Kapp, Michael P. Manns, Peter N. Meier, Jochen Wedemeyer, Alexander Kapp, Bettina Wedi, J Mayer, Michael Gebel, Yalcin Cetin, Stephan C. Bischoff
Publikováno v:
Gut. 40:745-753
BACKGROUND: The clinical relevance of gastrointestinal food allergy in adults is largely unknown because the mechanisms are poorly understood and the diagnosis is difficult to confirm. AIMS: To improve the diagnostic means for confirming intestinal f
Autor:
M. Kuhn, Rudolf Arnold, Michael P. Manns, H. Kulaksiz, R. Nold, Wolf-Georg Forssmann, Yalcin Cetin, Klaus H.W. Böker, Stephan C. Bischoff, Margareta Frank
Publikováno v:
European Journal of Clinical Investigation. 25:899-905
Guanylin is a recently discovered peptide hormone that activates intestinal guanylate cyclase (GC-C) and thereby stimulates intestinal chloride secretion. Immunohistochemistry showed its presence in enterochromaffin (EC) cells of the gut. In vitro st