Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Yakun Pang"'
Autor:
Hope L. Mumme, Sunil S. Raikar, Swati S. Bhasin, Beena E. Thomas, Taylor Lawrence, Elizabeth P. Weinzierl, Yakun Pang, Deborah DeRyckere, Chuck Gawad, Daniel S. Wechsler, Christopher C. Porter, Sharon M. Castellino, Douglas K. Graham, Manoj Bhasin
Publikováno v:
Genome Medicine, Vol 15, Iss 1, Pp 1-25 (2023)
Abstract Background Mixed phenotype acute leukemia (MPAL), a rare subgroup of leukemia characterized by blast cells with myeloid and lymphoid lineage features, is difficult to diagnose and treat. A better characterization of MPAL is essential to unde
Externí odkaz:
https://doaj.org/article/27b0d44d90b644919eac2539e49cde72
Autor:
Pengfei Qin, Yakun Pang, Wenhong Hou, Ruiqing Fu, Yingchi Zhang, Xuefei Wang, Guofeng Meng, Qifa Liu, Xiaofan Zhu, Ni Hong, Tao Cheng, Wenfei Jin
Publikováno v:
Cell Discovery, Vol 7, Iss 1, Pp 1-17 (2021)
Abstract Single-cell RNA sequencing provides exciting opportunities to unbiasedly study hematopoiesis. However, our understanding of leukemogenesis was limited due to the high individual differences. Integrated analyses of hematopoiesis and leukemoge
Externí odkaz:
https://doaj.org/article/a225aab84c74476f966ff4ba73d8dcfb
Autor:
Xiaomin Wang, Yanan Gao, Juan Gao, Minghao Li, Mi Zhou, Jinhong Wang, Yakun Pang, Hui Cheng, Chase Yuan, Yajing Chu, Yu Jiang, Jianfeng Zhou, Hongbo R. Luo, Zhenyu Ju, Tao Cheng, Weiping Yuan
Publikováno v:
Haematologica, Vol 104, Iss 2 (2019)
Hematopoietic stem cells constitute a unique subpopulation of blood cells that can give rise to all types of mature cells in response to physiological demands. However, the intrinsic molecular machinery that regulates this transformative property rem
Externí odkaz:
https://doaj.org/article/0fd1ce704ecf4e7693b9bce5686c5e83
Autor:
Yan Zhang, Fang Dong, Na Zhang, Hui Cheng, Yakun Pang, Xiaomin Wang, Jing Xu, Xinxin Ding, Tao Cheng, Jun Gu, Weiping Yuan
Publikováno v:
PLoS ONE, Vol 8, Iss 7, p e69913 (2013)
BACKGROUND: Bone marrow microenvironment (niche) plays essential roles in the fate of hematopoietic stem cells (HSCs). Intracellular and extracellular redox metabolic microenvironment is one of the critical factors for the maintenance of the niche. C
Externí odkaz:
https://doaj.org/article/3027a5e22d07472cb3ba37cbe5e4db98
Autor:
Joshua S. Schiffman, Andrew R. D’Avino, Tamara Prieto, Yakun Pang, Yilin Fan, Srinivas Rajagopalan, Catherine Potenski, Toshiro Hara, Mario L. Suvà, Charles Gawad, Dan A. Landau
SummaryThe broad application of single-cell RNA sequencing has revealed transcriptional cell state heterogeneity across diverse healthy and malignant somatic tissues. Recent advances in lineage tracing technologies have further enabled the simultaneo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::df30cd58af125a2cac5f017428ab11dd
https://doi.org/10.1101/2022.12.28.522128
https://doi.org/10.1101/2022.12.28.522128
Autor:
Valentin Barsan, Yuntao Xia, David Klein, Veronica Gonzalez-Pena, Sarah Youssef, Yuki Inaba, Ousman Mahmud, Sivaraman Natarajan, Vibhu Agarwal, Yakun Pang, Robert Autry, Ching-Hon Pui, Hiroto Inaba, William Evans, Charles Gawad
Publikováno v:
Science Advances. 8
Treatment of acute lymphoblastic leukemia (ALL) necessitates continuous risk assessment of leukemic disease burden and infections that arise in the setting of immunosuppression. This study was performed to assess the feasibility of a hybrid capture n
Autor:
Hiroto Inaba, Agarwal, Gonzalez-Pena, Yuki Inaba, David C. Klein, Yuntao Xia, Yakun Pang, Robert J Autry, Charles Gawad, William E. Evans, Youssef S, Barsan, Sivaraman Natarajan, Ousman Mahmud, C H Pui
Treatment of acute lymphoblastic leukemia (ALL) necessitates continuous risk assessment of leukemic disease burden as well as infections that arise in the setting of immunosuppression and myelosuppression. This study was performed to assess the feasi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::23e75f134f4b348835a671304f8de9bd
https://doi.org/10.1101/2021.03.30.21253149
https://doi.org/10.1101/2021.03.30.21253149
Autor:
Ruiqing Fu, Pengfei Qin, Tao Cheng, Guofeng Meng, Qifa Liu, Wenfei Jin, Xuefei Wang, Xiaofan Zhu, Yakun Pang, Yingchi Zhang, Ni Hong, Wenhong Hou
Publikováno v:
Cell Discovery
Cell Discovery, Vol 7, Iss 1, Pp 1-17 (2021)
Cell Discovery, Vol 7, Iss 1, Pp 1-17 (2021)
Single-cell RNA sequencing provides exciting opportunities to unbiasedly study hematopoiesis. However, our understanding of leukemogenesis was limited due to the high individual differences. Integrated analyses of hematopoiesis and leukemogenesis pot
Autor:
Sivaraman Natarajan, Robert A. Carter, Charles Gawad, Kavya Annu, Daniel Putnam, Jon P. Connelly, Bridget Shaner, John Easton, Yakun Pang, Veronica Gonzalez-Pena, David C. Klein, Xiang Chen, Wenan Chen, Shondra M. Pruett-Miller, Yuntao Xia
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Significance Primary template-directed amplification (PTA) is a major improvement in whole genome amplification, which is required to study intratissue cellular evolution. As presented in the manuscript, PTA produces significantly improved and reprod
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa9aec4d07d41cf48ba635d8737143d3
https://doi.org/10.1101/2020.11.20.391961
https://doi.org/10.1101/2020.11.20.391961
Autor:
Ruiqing Fu, Wenhong Hou, Yingchi Zhang, Qifa Liu, Guofeng Meng, Wenfei Jin, Ni Hong, Tao Cheng, Pengfei Qin, Xiaofan Zhu, Yakun Pang, Xuefei Wang
Integrated analyses of hematopoiesis and leukemogenesis could provide new biological and clinical insights1,2. Here we constructed a comprehensive cell atlas using ∼100,000 single cell transcriptomes of bone marrow mononuclear cells and its subsets
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::39644d75b488cafeb927cb978ef4a148