Zobrazeno 1 - 10 of 75 pro vyhledávání: '"Yajing Peng"'
1
Akademický článek
Double-proton transfer triggering mechanism of nitromethane caused by intermolecular hydrogen bonding at low temperature
Autor: Yajing Peng, Weina Liu, Bowen Ma, Jinshun Zhang, Yuhui Liu, Yan Su, Yanqiang Yang
Publikováno v: Arabian Journal of Chemistry, Vol 17, Iss 2, Pp 105579- (2024)
The initial triggering mechanism of nitromethane is investigated by first-principles molecular dynamics simulations and temperature-dependent Raman spectroscopy experiment. The Raman spectra at different temperature are obtained by Car-Parrinello mol
Externí odkaz: https://doaj.org/article/7051e447f6664990b09d303b82b2d08d
Zobrazit plný text záznamu
2
Akademický článek
ATase inhibition rescues age-associated proteotoxicity of the secretory pathway
Autor: Maeghan Murie, Yajing Peng, Michael J. Rigby, Inca A. Dieterich, Mark A. Farrugia, Andreas Endresen, Anita Bhattacharyya, Luigi Puglielli
Publikováno v: Communications Biology, Vol 5, Iss 1, Pp 1-12 (2022)
Murie et al use in silico docking and affinity binding to identify ATase1 and ATase2 specific inhibitors, and AT1 sTg and APP/PS1 mice to test their translational potential. Their study suggests that ATase-targeting approaches might offer a translati
Externí odkaz: https://doaj.org/article/33683ef18e5343e5a55dc7a73af44c2a
Zobrazit plný text záznamu
3
Akademický článek
Deficient Endoplasmic Reticulum Acetyl-CoA Import in Pancreatic Acinar Cells Leads to Chronic PancreatitisSummary
Autor: Michelle M. Cooley, Diana D.H. Thomas, Kali Deans, Yajing Peng, Aurelia Lugea, Stephen J. Pandol, Luigi Puglielli, Guy E. Groblewski
Publikováno v: Cellular and Molecular Gastroenterology and Hepatology, Vol 11, Iss 3, Pp 725-738 (2021)
Background & Aims: Maintaining endoplasmic reticulum (ER) proteostasis is essential for pancreatic acinar cell function. Under conditions of severe ER stress, activation of pathogenic unfolded protein response pathways plays a central role in the dev
Externí odkaz: https://doaj.org/article/5dd29e6836a94d13869244ae95e51c4a
Zobrazit plný text záznamu
4
Akademický článek
Comprehension of the Synergistic Effect between m&t-BiVO4/TiO2-NTAs Nano-Heterostructures and Oxygen Vacancy for Elevated Charge Transfer and Enhanced Photoelectrochemical Performances
Autor: Zhufeng Shao, Jianyong Cheng, Yonglong Zhang, Yajing Peng, Libin Shi, Min Zhong
Publikováno v: Nanomaterials, Vol 12, Iss 22, p 4042 (2022)
Through the utilization of a facile procedure combined with anodization and hydrothermal synthesis, highly ordered alignment TiO2 nanotube arrays (TiO2-NTAs) were decorated with BiVO4 with distinctive crystallization phases of monoclinic scheelite (m
Externí odkaz: https://doaj.org/article/e8125862dc3b40668624c9720df17588
Zobrazit plný text záznamu
5
Akademický článek
Acetyl-CoA flux regulates the proteome and acetyl-proteome to maintain intracellular metabolic crosstalk
Autor: Inca A. Dieterich, Alexis J. Lawton, Yajing Peng, Qing Yu, Timothy W. Rhoads, Katherine A. Overmyer, Yusi Cui, Eric A. Armstrong, Porsha R. Howell, Maggie S. Burhans, Lingjun Li, John M. Denu, Joshua J. Coon, Rozalyn M. Anderson, Luigi Puglielli
Publikováno v: Nature Communications, Vol 10, Iss 1, Pp 1-11 (2019)
The Endoplasmic Reticulum acetylation machinery ensures proper quality control and disposal of newly folded proteins transiting the secretory pathway. Here, the authors show that this machinery acts as a metabolic regulator of acetyl-CoA homeostasis,
Externí odkaz: https://doaj.org/article/0d4577b03c594bb194303bbedd2c9a54
Zobrazit plný text záznamu
6
Akademický článek
ATG9A regulates proteostasis through reticulophagy receptors FAM134B and SEC62 and folding chaperones CALR and HSPB1
Autor: Brendan K. Sheehan, Nicola S. Orefice, Yajing Peng, Samantha L. Shapiro, Luigi Puglielli
Publikováno v: iScience, Vol 24, Iss 4, Pp 102315- (2021)
Summary: The acetylation of ATG9A within the endoplasmic reticulum (ER) lumen regulates the induction of reticulophagy. ER acetylation is ensured by AT-1/SLC33A1, a membrane transporter that maintains the cytosol-to-ER flux of acetyl-CoA. Defective A
Externí odkaz: https://doaj.org/article/81a9a530c93a49ca93533c48bb9490b0
Zobrazit plný text záznamu
7
The endoplasmic reticulum acetyl-CoA transporter AT-1 plays a role in the protective unfolded protein response in the exocrine pancreas
Autor: Michelle Cooley, Diana Thomas, Kali Deans-Fielder, Yajing Peng, Aurelia Lugea, Richard Waldron, Stephen Pandol, Luigi Puglielli, Guy Groblewski
Publikováno v: Physiology. 38
Pancreatic acinar cells are responsible for the synthesis and secretion of digestive enzymes. In order to sustain high rates of secretory protein production, acinar cells rely on adaptive mechanisms to mitigate endoplasmic reticulum (ER) stress and m
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::76439c69f37b39e56f427b5b79a83fe3
https://doi.org/10.1152/physiol.2023.38.s1.5733158
Zobrazit plný text záznamu
10
Deficient Endoplasmic Reticulum Acetyl-CoA Import in Pancreatic Acinar Cells Leads to Chronic Pancreatitis
Autor: Guy E. Groblewski, Kali Deans, Michelle M. Cooley, Luigi Puglielli, Stephen J. Pandol, Aurelia Lugea, Yajing Peng, Diana D. H. Thomas
Publikováno v: Cellular and Molecular Gastroenterology and Hepatology, Vol 11, Iss 3, Pp 725-738 (2021)
Cellular and Molecular Gastroenterology and Hepatology
Background & Aims Maintaining endoplasmic reticulum (ER) proteostasis is essential for pancreatic acinar cell function. Under conditions of severe ER stress, activation of pathogenic unfolded protein response pathways plays a central role in the deve
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ff62c51953438aac0781c359ade92ac
https://doi.org/10.1016/j.jcmgh.2020.10.008
Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání

Omezení vyhledávání
Plný text Recenzováno Digitální knihovna AV ČR
Zdroje