Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Yajing Chi"'
Autor:
Xian An, Zhuang Chen, Yi Luo, Peng Yang, Zuo Yang, Tiannan Ji, Yajing Chi, Shuyuan Wang, Ruili Zhang, Zhongliang Wang, Jianxiong Li
Publikováno v:
Advanced Science, Vol 11, Iss 33, Pp n/a-n/a (2024)
Abstract In situ cancer vaccination is an attractive strategy that stimulates protective antitumor immunity. Cytotoxic T lymphocytes (CTLs) are major mediators of the adaptive immune defenses, with critical roles in antitumor immune response and esta
Externí odkaz:
https://doaj.org/article/2fe4428658524d7f8f2e11fec365f49f
Autor:
Yajing Chi, Mu Su, Dongdong Zhou, Fangchao Zheng, Baoxuan Zhang, Ling Qiang, Guohua Ren, Lihua Song, Bing Bu, Shu Fang, Bo Yu, Jinxing Zhou, Jinming Yu, Huihui Li
Publikováno v:
eLife, Vol 12 (2023)
Background: Limited data are available on applying circulating tumor DNA (ctDNA) in metastatic triple-negative breast cancer (mTNBC) patients. Here, we investigated the value of ctDNA for predicting the prognosis and monitoring the treatment response
Externí odkaz:
https://doaj.org/article/3f5cef1ce94744cdab0d167054998cb3
Autor:
Sha Yin, Yajing Chi, Yangyang Du, Jingfen Wang, Changping Shan, Weiwei Yi, Mao Shang, Xiaochu Man, Qiaorui Tan, Huihui Li
Publikováno v:
Cancer Medicine, Vol 12, Iss 3, Pp 2333-2344 (2023)
Abstract Background Pyrotinib, a novel irreversible epidermal growth factor receptor 2 (EGFR)/HER2 dual tyrosine kinase inhibitor, has shown promising antitumor efficacy with tolerable toxicity in HER2‐positive metastatic breast cancer (MBC) in sev
Externí odkaz:
https://doaj.org/article/462a0e8cef044d55a9f601770ef2bba2
Autor:
Qiaorui Tan, Yajing Chi, Mu Su, Jinxing Zhou, Dongdong Zhou, Fangchao Zheng, Xiaochu Man, Shujuan Sun, Jie Huang, Huihui Li
Publikováno v:
Frontiers in Genetics, Vol 14 (2023)
Background: In recent years, tumor immunotherapy has become a viable treatment option for triple negative breast cancer (TNBC). Among these, immune checkpoint inhibitors (ICIs) have demonstrated good efficacy in advanced TNBC patients with programmed
Externí odkaz:
https://doaj.org/article/a4c2d839aa8049a1a7ba9a6b213e1e7a
Autor:
Tiannan Ji, Xiaohui Gao, Dan Li, Siyuan Huai, Yajing Chi, Xian An, Wenyu Ji, Siming Yang, Jianxiong Li
Publikováno v:
Frontiers in Oncology, Vol 12 (2023)
BackgroundN6-methyladenosine (m6A) RNA regulators play important roles in cancers, but their functions and mechanism have not been demonstrated clearly in gastric cancer (GC).MethodsIn this study, the GC samples with clinical information and RNA tran
Externí odkaz:
https://doaj.org/article/0d7adbe159ed41868171cc80df48b7fa
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
As an aggressive subtype of breast cancer, triple-negative breast cancer (TNBC) is associated with poor prognosis and lack of effective therapy, except chemotherapy. In recent years, immunotherapy based on immune checkpoint (IC) inhibition has emerge
Externí odkaz:
https://doaj.org/article/09ad7adbd0c248909dc02502e5489a7e
Autor:
Yajing Chi, Mao Shang, Liang Xu, Heyi Gong, Rongjie Tao, Lihua Song, Baoxuan Zhang, Sha Yin, Binbin Cong, Huihui Li
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
Leptomeningeal metastases (LM) are rare and catastrophic for metastatic breast cancer (MBC). The prognosis of HER2-positive breast cancer (BC) with LM is extremely poor. There is no high-quality evidence of treatment regimens in HER2-positive BC with
Externí odkaz:
https://doaj.org/article/d50e93be61ad4b9c8aeb2d082f7e69d3
Autor:
Mao Shang, Yajing Chi, Jianbo Zhang, Jin Chang, Hui Yang, Sha Yin, Qiaorui Tan, Xiaochu Man, Huihui Li
Publikováno v:
Frontiers in Oncology, Vol 11 (2022)
IntroductionNeoadjuvant trastuzumab plus chemotherapy may affect programmed death-ligand 1 (PD-L1) expression and tumor-infiltrating lymphocytes (TILs) in HER2-positive breast cancer. Discordant results were shown on the correlation between PD-L1 exp
Externí odkaz:
https://doaj.org/article/54712d6ac5ad4e7f88624298129bee55
Publikováno v:
Frontiers in Aging Neuroscience, Vol 10 (2018)
Both alpha-synuclein aggregation and iron deposits are neuropathological hallmarks of Parkinson’s disease (PD). We are particularly interested in whether iron could synergize with alpha-synuclein pathology in vivo, especially in the nigrostriatal s
Externí odkaz:
https://doaj.org/article/34235a8d7bff47ae8aae300e34ff3e0b
Autor:
Huihui Li, Yajing Chi, Sha Yin, Bo Yu, Mu Su, Baoxuan Zhang, Ling Qiang, Guohua Ren, Lihua Song, Bing Bu, Shu Fang, Mao Shang, Qiaorui Tan, Xiaochu Man
Publikováno v:
Cancer Research. 82:P1-08
Background: Chemotherapy is the main treatment for metastatic triple-negative breast cancer (mTNBC). However, mTNBC patients (pts) is often associated with chemotherapy resistance and poor prognosis. Biomarkers that can effectively predict the effica