Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Yair Pozniak"'
Autor:
Kobi Perl, Kathy Ushakov, Yair Pozniak, Ofer Yizhar-Barnea, Yoni Bhonker, Shaked Shivatzki, Tamar Geiger, Karen B. Avraham, Ron Shamir
Publikováno v:
BMC Genomics, Vol 18, Iss 1, Pp 1-14 (2017)
Abstract Background The quantitative relations between RNA and protein are fundamental to biology and are still not fully understood. Across taxa, it was demonstrated that the protein-to-mRNA ratio in steady state varies in a direction that lessens t
Externí odkaz:
https://doaj.org/article/9df7bd0206664029bc89d15343d4f5e2
Autor:
Hadar Brand, Keren Bahar-Shany, Tamar Geiger, Yair Pozniak, Jasmine Jacob-Hirsch, Keren Levanon, Yuval Yung, Georgina D. Barnabas, Stav Sapoznik, Ariel Hourvitz
Publikováno v:
Carcinogenesis. 41:1703-1712
The fallopian tube secretory epithelial cells (FTSECs) are the cell-of-origin of most high-grade serous ovarian carcinomas (HGSOC). FTSECs are repeatedly exposed to inflammation induced by follicular fluid (FF) that is released with every ovulation c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4fef159f594c6349806200bb2470fcea
https://doi.org/10.1093/carcin/bgaa068
https://doi.org/10.1093/carcin/bgaa068
Autor:
Francesca Demichelis, Georgina D. Barnabas, Paola Gasperini, Erez Persi, Yuri I. Wolf, David Horn, Davide Prandi, Christopher E. Barbieri, Himisha Beltran, Eugene V. Koonin, Tamar Geiger, Yair Pozniak, Keren Levanon, Mark A. Rubin, Iris Barshack, Bishoy Faltas
Repetitive sequences are hotspots of evolution at multiple levels. However, due to difficulties involved in their assembly and analysis, the role of repeats in tumor evolution is poorly understood. We developed a rigorous motif-based methodology to q
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c0a4a11dcdb2e54c7307a28f9c6e516
https://europepmc.org/articles/PMC6708321/
https://europepmc.org/articles/PMC6708321/
Autor:
Francesca Demichelis, Eugene V. Koonin, Christopher E. Barbieri, Bishoy Faltas, Mark A. Rubin, Erez Persi, David Horn, Paola Gasperini, Davide Prandi, Himisha Beltran, Tamar Geiger, Yair Pozniak, Yuri I. Wolf
SummaryRepetitive sequences are hotspots of evolution at multiple levels. However, due to technical difficulties involved in their assembly and analysis, the role of repeats in tumor evolution is poorly understood. We developed a rigorous motif-based
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d78dc59d1289e37caf5a543b88ec9dbc
https://doi.org/10.1101/491423
https://doi.org/10.1101/491423
Publikováno v:
Oncotarget
// Shilhav Meisel Sharon 1 , Yair Pozniak 1 , Tamar Geiger 1 , Haim Werner 1, 2 1 Department of Human Molecular Genetics and Biochemistry, Sackler School of Medicine, Tel Aviv University, Tel Aviv 69978, Israel 2 Yoran Institute for Human Genome Rese
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::038b2891227bf4ae9c869db060a2361f
http://europepmc.org/articles/PMC5239482
http://europepmc.org/articles/PMC5239482
Autor:
Iris Barshack, Cecilia Lindskog, Tamar Geiger, Nora Balint-Lahat, Rotem Katzir, Fredrik Pontén, Jan Daniel Rudolph, Camilla Avivi, Yair Pozniak, Eytan Ruppin
Publikováno v:
Cell Systems. 2(3):172-184
The genomic and transcriptomic landscapes of breast cancer have been extensively studied, but the proteomes of breast tumors are far less characterized. Here, we use high-resolution, high-accuracy mass spectrometry to perform a deep analysis of lumin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b13fdfd80e454cf791891b102fc4e4b
Publikováno v:
Molecular genetics and metabolism. 126(3)
The insulin-like growth factor-1 receptor (IGF1R) mediates the biological actions of both IGF1 and IGF2. In recent years, evidence has accumulated showing that, in addition to its classical cell-surface distribution, IGF1R translocates to cell nucleu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f64586aa848bee8c06f614e58e7a7248
https://pubmed.ncbi.nlm.nih.gov/30639046
https://pubmed.ncbi.nlm.nih.gov/30639046
Publikováno v:
Oncogene. 34:6066-6078
Although cysteine cathepsins have been identified as key regulators of cancer growth, their specific role in tumor development remains unclear. Recent studies have shown that high activity levels of tumor cathepsins are primarily a result of increase
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7becd0ccae8233647da0072b6bcaf233
https://doi.org/10.1038/onc.2015.51
https://doi.org/10.1038/onc.2015.51
Autor:
Joo Sang Lee, Georgina D. Barnabas, Eytan Ruppin, Michael Selitrennik, Livnat Jerby Arnon, Michal Harel, Tamar Geiger, Yair Pozniak, Eyal Gottlieb
Publikováno v:
ESMO Open. 3:A124-A125
Introduction Reprogrammed energy metabolism is one among the distinguished cancer hallmarks that unravels the dysregulated bioenergetics of cancer cells. Isocitrate dehydrogenase 2 (IDH2), a mitochondrial metabolic enzyme has been reported to be over
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c6f8130548d37e06312509ae300e2ce7
https://doi.org/10.1136/esmoopen-2018-eacr25.298
https://doi.org/10.1136/esmoopen-2018-eacr25.298
Autor:
Patricia A. Jennings, Mingyang Lu, Eli Pikarsky, Fang Bai, Ron Mittler, José N. Onuchic, Merav Darash-Yahana, Yang Sung Sohn, Sagi Tamir, Luhua Song, Yair Pozniak, Ola Karmi, Rachel Nechushtai, Tamar Geiger
Iron-sulfur (Fe-S) proteins are thought to play an important role in cancer cells mediating redox reactions, DNA replication, and telomere maintenance. Nutrient-deprivation autophagy factor-1 (NAF-1) is a 2Fe-2S protein associated with the progressio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09457b622ff21c10b1d1d58ca807d20c
https://europepmc.org/articles/PMC5047192/
https://europepmc.org/articles/PMC5047192/