Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Yahya E. Jad"'
Autor:
Shimaa A. H. Abdel Monaim, Yahya E. Jad, Estelle J. Ramchuran, Ayman El-Faham, Thavendran Govender, Hendrik G. Kruger, Beatriz G. de la Torre, Fernando Albericio
Publikováno v:
ACS Omega, Vol 1, Iss 6, Pp 1262-1265 (2016)
Externí odkaz:
https://doaj.org/article/d0da3c85d6b4482c9cf43c844e11269d
Autor:
Yahya E. Jad, Sherine N. Khattab, Beatriz G. de la Torre, Thavendran Govender, Hendrik G. Kruger, Ayman El-Faham, Fernando Albericio
Publikováno v:
Molecules, Vol 19, Iss 11, Pp 18953-18965 (2014)
Here we describe two novel uronium salts, TOMBU and COMBU, derived from the recently described Oxyma-B for use in peptide bond synthesis. These coupling reagents are more stable than COMU in DMF. Furthermore, using various peptide synthetic models in
Externí odkaz:
https://doaj.org/article/c92f309c4df141ff9ed81d1ea281af99
Autor:
Fernando Albericio, Shimaa A. H. Abdel Monaim, Yahya E. Jad, Gerardo A. H. Acosta, Estelle J. Ramchuran, Ayman El-Faham, Thavendran Govender, Hendrik G. Kruger, Beatriz G. de la Torre
Publikováno v:
Proceedings, Vol 1, Iss 6, p 671 (2017)
The emergence of multidrug resistant bacteria has a direct impact on global public health due to the reduced potency of existing antibiotics against pathogens [1]. [...]
Externí odkaz:
https://doaj.org/article/c897f2cd6696438189c8b53368841ec0
Autor:
Anamika Sharma, Yahya E. Jad, Hazem A. Ghabbour, Beatriz G. de la Torre, Hendrik G. Kruger, Fernando Albericio, Ayman El-Faham
Publikováno v:
Crystals, Vol 7, Iss 1, p 31 (2017)
Novel 1,3-Dimethyl-5-propionylpyrimidine-2,4,6(1H,3H,5H)-trione was synthesized and recrystallized from ethanol. The compound was characterized by 1H NMR, 13C NMR in CDCl3, DMSO-d6 and acetone-d6, elemental analysis and X-ray diffraction. The NMR dat
Externí odkaz:
https://doaj.org/article/36080a6643974716bbcdbcc45ecf1e1b
Publikováno v:
ACS Sustainable Chemistry & Engineering. 7:3671-3683
Peptides play key roles in medicinal chemistry, being found in therapeutics and diagnostic agents, among others. Furthermore, their synthetic protocols have also been optimized for other fields such as the solid-phase organic synthesis of other organ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::25261d6295979bf6231f6a34d62a96cb
https://doi.org/10.1021/acssuschemeng.8b06520
https://doi.org/10.1021/acssuschemeng.8b06520
Publikováno v:
Letters in Organic Chemistry. 16:30-33
A new phosphonium based coupling reagent DEPO-B has been synthesized from 5- (hydroxyimino)-1,3-dimethylpyrimidine-2,4,6 (1H,3H,5H)-trione (Oxyma B) and diethyl chlorophosphate in presence of base. It is a solid material and the hydrolytic stability
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e74a303739991c4189d3718bca49fd69
https://doi.org/10.2174/1570178615666180612074420
https://doi.org/10.2174/1570178615666180612074420
Publikováno v:
ACS Sustainable Chemistry & Engineering. 6:8034-8039
The increasing demand for synthetic peptides in various research fields raises a challenge, namely, the development of greener methods for their preparation. Here we report on an ecofriendly solid-phase peptide synthesis (SPPS) methodology. Substitut
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b0d8059447367fbd2e7dc7b12356e977
https://doi.org/10.1021/acssuschemeng.8b01531
https://doi.org/10.1021/acssuschemeng.8b01531
Publikováno v:
Journal of Peptide Science. 23:763-768
COMU is uronium-type coupling reagent based on OxymaPure. It showed several advantages over classical benzotriazole-based coupling reagents such as higher solubility, water-soluble byproduct, and monitoring the reaction by changing of color. Although
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7d4de6561e1af7f9b6dc3699b88a3914
https://doi.org/10.1002/psc.3024
https://doi.org/10.1002/psc.3024
Autor:
Hendrik G. Kruger, Gerardo A. Acosta, Yahya E. Jad, Beatriz G. de la Torre, Ayman El-Faham, Thavendran Govender, Fernando Albericio
Publikováno v:
ACS Sustainable Chemistry & Engineering. 4:6809-6814
N,N-Dimethylformamide (DMF), N-methyl-2-pyrrolidone, and dichloromethane (DCM) are the most widely used solvents for Fmoc solid-phase peptide synthesis (SPPS). These solvents are considered hazardous chemicals and are normally used in large amounts f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d49f6b24fb894b8529ab411b87ff23e5
https://doi.org/10.1021/acssuschemeng.6b01765
https://doi.org/10.1021/acssuschemeng.6b01765
Autor:
Melissa Ramtahal, Hendrik G. Kruger, Thavendran Govender, Ayman El-Faham, Gerardo A. Acosta, Beatriz G. de la Torre, Yahya E. Jad, Tricia Naicker, Fernando Albericio
Publikováno v:
Organic Letters. 17:6182-6185
The first synthesis and biological activity of a teixobactin analogue is reported. Substitution of the unusual L-allo-enduracididine residue by the naturally occurring L-arginine was achieved, and the analogue gave an activity trend similar to that o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::93083257cbd7ac76b15a164abcb1283e
https://doi.org/10.1021/acs.orglett.5b03176
https://doi.org/10.1021/acs.orglett.5b03176