Zobrazeno 1 - 10
of 77
pro vyhledávání: '"Yahui Yan"'
Publikováno v:
Journal of Functional Foods, Vol 121, Iss , Pp 106402- (2024)
Terminalia chebula Retz. is commonly used in the treatment of diabetes, but its specific ingredients and hypoglycaemic mechanisms remain unclear. In this study, spectrum-effect relationships between common peaks of fingerprint and DPPH, ABTS, PTP1B,
Externí odkaz:
https://doaj.org/article/7a60dbeb58124ffaa77f3cd17f3bf399
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-15 (2019)
The role of mesencephalic astrocyte-derived neurotrophic factor (MANF) in maintenance of protein folding homeostasis inside the ER has remained unclear. Here the authors determine the structure of the complex between MANF and the ER-localized chapero
Externí odkaz:
https://doaj.org/article/29a9184db10c451b966d07b035dde1b3
Publikováno v:
eLife, Vol 9 (2020)
The metazoan endoplasmic reticulum (ER) serves both as a hub for maturation of secreted proteins and as an intracellular calcium storage compartment, facilitating calcium-release-dependent cellular processes. ER calcium depletion robustly activates t
Externí odkaz:
https://doaj.org/article/2df68a40864044a2966b41fdb69dcf50
Publikováno v:
eLife, Vol 8 (2019)
Coupling of endoplasmic reticulum (ER) stress to dimerisation-dependent activation of the UPR transducer IRE1 is incompletely understood. Whilst the luminal co-chaperone ERdj4 promotes a complex between the Hsp70 BiP and IRE1’s stress-sensing lumin
Externí odkaz:
https://doaj.org/article/6243d75368fa4ac6bb92dcb63e2aed61
Publikováno v:
eLife, Vol 6 (2017)
The endoplasmic reticulum (ER)-localized Hsp70 chaperone BiP contributes to protein folding homeostasis by engaging unfolded client proteins in a process that is tightly coupled to ATP binding and hydrolysis. The inverse correlation between BiP AMPyl
Externí odkaz:
https://doaj.org/article/dea71c6fa26646bfb0446cd3cef77811
Autor:
Ruming Chen, Cláudia Rato, Yahui Yan, Ana Crespillo-Casado, Hanna J Clarke, Heather P Harding, Stefan J Marciniak, Randy J Read, David Ron
Publikováno v:
eLife, Vol 4 (2015)
Dephosphorylation of eukaryotic translation initiation factor 2a (eIF2a) restores protein synthesis at the waning of stress responses and requires a PP1 catalytic subunit and a regulatory subunit, PPP1R15A/GADD34 or PPP1R15B/CReP. Surprisingly, PPP1R
Externí odkaz:
https://doaj.org/article/d50ab94c81404b48bb62ce3b1f3927bf
Autor:
Yahui Yan, Shetty, Maithili, Harding, Heather P., George, Ginto, Zyryanova, Alisa, Labbé, Katherine, Mafi, Amirhossein, Qi Hao, Sidrauski, Carmela, Ron, David
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America; 4/2/2024, Vol. 121 Issue 14, p1-12, 42p
Publikováno v:
Journal of Chromatographic Science. 61:312-321
An integrated strategy was developed for the systematic chemical fingerprint and chemometrics analysis for the quality assessment of Aloe vera (L.) Burm. f. The ultra-performance liquid chromatography fingerprint was established, and all common peaks
Publikováno v:
Journal of Separation Science. 45:2148-2160
The Shabyar tablet is commonly used as a traditional ethnic medicine prescription for the treatment of night blindness, poor vision, and headaches. However, the chemical components of the Shabyar tablet have not been holistically explored, which seri
Autor:
Cavan Bennett, Moyra Lawrence, Jose A. Guerrero, Simon Stritt, Amie K. Waller, Yahui Yan, Richard W. Mifsud, Jose Ballester-Beltrán, Ayesha Baig, Annett Mueller, Louisa Mayer, James Warland, Christopher J. Penkett, Parsa Akbari, Thomas Moreau, Amanda L. Evans, Souradip Mookerjee, Gary J. Hoffman, Kourosh Saeb-Parsy, David J. Adams, Amber L. Couzens, Markus Bender, Wendy N. Erber, Bernhard Nieswandt, Randy J. Read, Cedric Ghevaert
Publikováno v:
Blood. 139:2227-2239
The process of platelet production has so far been understood to be a 2-stage process: megakaryocyte maturation from hematopoietic stem cells followed by proplatelet formation, with each phase regulating the peripheral blood platelet count. Proplatel