Zobrazeno 1 - 10
of 56
pro vyhledávání: '"Yahuan Lou"'
Autor:
Yahuan Lou
Publikováno v:
Neuroscience Insights, Vol 16 (2021)
Late-onset Alzheimer’s disease (LOAD) is the most common age-related dementia, and its etiology remains unclear. Recent studies have linked abnormal neuronal aging to LOAD. Neurons are non-proliferative, and thus, majority of aged neurons must be r
Externí odkaz:
https://doaj.org/article/f52db248df614dc2aa7ead123c03a778
Autor:
Yahuan Lou
Publikováno v:
American Journal of Biomedical Science & Research. 15:632-636
Autor:
João Quevedo, Colin Carlock, Yahuan Lou, Jean Wu, Tatiana Barichello, William F Glass, April Ross, Junbo Shim, Ines Moreno-Gonzalez
Publikováno v:
Molecular Psychiatry
Defective aquaporin4 (AQP4)-mediated glymphatic drainage has been linked to tauopathy and amyloid plaque in Alzheimer’s disease. We now show that brain interleukin33 (IL33) is required for regulation of AQP4 expression in astrocytes, especially tho
Publikováno v:
Biomark Appl
Alzheimer’s Disease or other dementias are characterized by the accumulation of abnormal tau and amyloid β peptides in brains. Therefore, abnormal tau and amyloid peptides in peripheral tissues or blood have been explored as diagnostic biomarkers.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b499aada4bd8d17dda92e9a9526b94d
https://europepmc.org/articles/PMC7729990/
https://europepmc.org/articles/PMC7729990/
Publikováno v:
PLoS ONE, Vol 13, Iss 8, p e0202988 (2018)
Inter-molecular epitope spreading during autoimmune pathogenesis leads to generation of new pathogenic epitopes on other autoantigens beyond the original one. It raises an important question as whether autoimmunity extends beyond the target tissues i
Autor:
Yahuan Lou, Kristie Lou, Todd Bartkowiak, Cindy Zhou, Kiana Tatum, David Kagan, Jean Wu, Jeremiah Funk
Publikováno v:
American Journal of Nephrology. 42:42-53
Background: Many types of glomerulonephritis (GN) undergo tandem connected phases: inflammation and fibrosis. Fibrosis in human GNs leads to irreversible end-stage disease. This study investigated how these 2 phases were controlled. Methods: Using a
Publikováno v:
The Journal of Immunology. 193:161-169
Ovaries are among the most active organs. Frequently occurring events such as ovulation and ovarian atresia are accompanied with tissue destruction and repairing. Critical roles of immune cells or molecules in those events have been well recognized.
Publikováno v:
Journal of Affective Disorders. 254:139
Publikováno v:
Kidney international
In an anti-glomerular basement membrane (GBM) glomerulonephritis (GN) model, GN-resistant Lewis rats naturally recover from early glomerular inflammation. Here we investigated recovery mechanisms for development of a potential immunotherapy for autoi
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 197(11)
Discovery of immune tolerance mechanisms, which inhibit pre-existing autoimmune inflammation, may provide us with new strategies for treating autoimmune diseases. We have identified a CD8αα+MHC class II+ cell with professional APC capacity during o