Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Yago Margolles"'
Autor:
Alejandro Prieto, Luïsa Miró, Yago Margolles, Manuel Bernabeu, David Salguero, Susana Merino, Joan Tomas, Juan Alberto Corbera, Anna Perez-Bosque, Mario Huttener, Luis Ángel Fernández, Antonio Juarez
Publikováno v:
eLife, Vol 13 (2024)
Antimicrobial resistance (AMR) poses a significant threat to human health. Although vaccines have been developed to combat AMR, it has proven challenging to associate specific vaccine antigens with AMR. Bacterial plasmids play a crucial role in the t
Externí odkaz:
https://doaj.org/article/f7646182647d497e95517f001fbd4d79
Autor:
Yamal Al-ramahi, Akos Nyerges, Yago Margolles, Lidia Cerdán, Gyorgyi Ferenc, Csaba Pál, Luis Ángel Fernández, Víctor de Lorenzo
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-11 (2021)
Yamal Al-ramahi et al. describe an accelerated laboratory evolution method that applies ssDNA recombineering and bacterial surface display to engineer nanobody epitope recognition. As a proof-of-concept, they evolved TD4 recognition to bind the trans
Externí odkaz:
https://doaj.org/article/7cfb63c37a134a1381dcf213cbee4ff5
Autor:
Francisca Mulero, Marta Oteo, Guillermo Garaulet, Natalia Magro, Lluvia Rebollo, Guillermo Medrano, Clara Santiveri, Eduardo Romero, Ricela E. Sellek, Yago Margolles, Ramón Campos-Olivas, Alicia G. Arroyo, Luis Angel Fernández, Miguel Angel Morcillo, Jorge L. Martínez-Torrecuadrada
Publikováno v:
Frontiers in Medicine, Vol 9 (2022)
Triple-negative breast cancer (TNBC) is characterized by aggressiveness and high rates of metastasis. The identification of relevant biomarkers is crucial to improve outcomes for TNBC patients. Membrane type 1-matrix metalloproteinase (MT1-MMP) could
Externí odkaz:
https://doaj.org/article/9f56d62e2e19476389ae4a1143daab5c
Autor:
Guillermo Valenzuela Nieto, Ronald Jara, Daniel Watterson, Naphak Modhiran, Alberto A. Amarilla, Johanna Himelreichs, Alexander A. Khromykh, Constanza Salinas-Rebolledo, Teresa Pinto, Yorka Cheuquemilla, Yago Margolles, Natalia López González del Rey, Zaray Miranda-Chacon, Alexei Cuevas, Anne Berking, Camila Deride, Sebastián González-Moraga, Héctor Mancilla, Daniel Maturana, Andreas Langer, Juan Pablo Toledo, Ananda Müller, Benjamín Uberti, Paola Krall, Pamela Ehrenfeld, Javier Blesa, Pedro Chana-Cuevas, German Rehren, David Schwefel, Luis Ángel Fernandez, Alejandro Rojas-Fernandez
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-14 (2021)
Abstract Despite unprecedented global efforts to rapidly develop SARS-CoV-2 treatments, in order to reduce the burden placed on health systems, the situation remains critical. Effective diagnosis, treatment, and prophylactic measures are urgently req
Externí odkaz:
https://doaj.org/article/ee67da82c4154da782d61078ae559f70
Autor:
José M. Casasnovas, Yago Margolles, María A. Noriega, María Guzmán, Rocío Arranz, Roberto Melero, Mercedes Casanova, Juan Alberto Corbera, Nereida Jiménez-de-Oya, Pablo Gastaminza, Urtzi Garaigorta, Juan Carlos Saiz, Miguel Ángel Martín-Acebes, Luis Ángel Fernández
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
The emergence of SARS-CoV-2 variants that escape from immune neutralization are challenging vaccines and antibodies developed to stop the COVID-19 pandemic. Thus, it is important to establish therapeutics directed toward multiple or specific SARS-CoV
Externí odkaz:
https://doaj.org/article/ba7beffeff9e43119f483924e5cf5790
Autor:
Valencio Salema, Elvira Marín, Rocio Martínez-Arteaga, David Ruano-Gallego, Sofía Fraile, Yago Margolles, Xema Teira, Carlos Gutierrez, Gustavo Bodelón, Luis Ángel Fernández
Publikováno v:
PLoS ONE, Vol 8, Iss 9, p e75126 (2013)
Screening of antibody (Ab) libraries by direct display on the surface of E. coli cells is hampered by the presence of the outer membrane (OM). In this work we demonstrate that the native β-domains of EhaA autotransporter and intimin, two proteins fr
Externí odkaz:
https://doaj.org/article/81bfbbccc93b40b7a22a898ad0246a8b
Autor:
Gisela Ruiz-Vega, Maria Soler, M. Carmen Estevez, Patricia Ramirez-Priego, Martalu D. Pazos, María A. Noriega, Yago Margolles, Clara Francés-Gómez, Ron Geller, Giulia Matusali, Francesca Colavita, Antonino di Caro, José M. Casasnovas, Luis Angel Fernández, Laura M. Lechuga
The coronavirus (CoV) disease 2019 (COVID-19) is expected to become endemic in the coming years, meaning that the worldwide society shall be prepared to routinely manage the highly contagious respiratory SARS-CoV-2. A rapid and early diagnosis of the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5bb620de2d9cf686e42f8720ff901753
http://hdl.handle.net/10261/308325
http://hdl.handle.net/10261/308325
Autor:
Víctor de Lorenzo, Yamal Al-Ramahi, Ákos Nyerges, Györgyi Ferenc, Lidia Cerdán, Csaba Pál, Yago Margolles, Luis Ángel Fernández
Publikováno v:
Communications Biology
Communications Biology, Vol 4, Iss 1, Pp 1-11 (2021)
Communications Biology, Vol 4, Iss 1, Pp 1-11 (2021)
ssDNA recombineering has been exploited to hyperdiversify genomically-encoded nanobodies displayed on the surface of Escherichia coli for originating new binding properties. As a proof-of-principle a nanobody recognizing the antigen TirM from enteroh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::efc60e7281db791cbbba1af9a36076f0
https://doi.org/10.1101/2021.01.28.428624
https://doi.org/10.1101/2021.01.28.428624
Autor:
Pedro Chana-Cuevas, German Rehren, Paola Krall, Alberto A. Amarilla, Natalia Lopez-Gonzalez del Rey, Naphak Modhiran, Ananda Müller, Guillermo E. Valenzuela Nieto, Yorka Cheuquemilla, Juan Pablo Toledo, Javier Blesa, Benjamin Uberti, David Schwefel, Ronald Jara, Anne Berking, Teresa Pinto, Constanza Salinas-Rebolledo, Camila Deride, Alexei Cuevas, Daniel Maturana, Daniel Watterson, Luis Ángel Fernández, Héctor Mancilla, Yago Margolles, Pamela Ehrenfeld, Sebastián González-Moraga, Alejandro Rojas-Fernandez, Zaray Miranda-Chacon, Johanna Himelreichs, Alexander A. Khromykh, Andreas Langer
Publikováno v:
Scientific Reports
Scientific Reports, Vol 11, Iss 1, Pp 1-14 (2021)
Scientific Reports, Vol 11, Iss 1, Pp 1-14 (2021)
Despite unprecedented global efforts to rapidly develop SARS-CoV-2 treatments, in order to reduce the burden placed on health systems, the situation remains critical. Effective diagnosis, treatment, and prophylactic measures are urgently required to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::66d12ac559ac524cc6d23f661febcaef
https://doi.org/10.1101/2020.06.09.137935
https://doi.org/10.1101/2020.06.09.137935