Zobrazeno 1 - 10
of 80
pro vyhledávání: '"Yagna P R Jarajapu"'
Autor:
Reed Jacobson, Sangdeuk Ha, Sakurako Tani, Shrinwanti Ghosh, Yagna P. R. Jarajapu, Randall E. Brand, Jiha Kim, Yongki Choi
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-8 (2024)
Abstract Tumor-derived extracellular vesicles (EVs) show great potential as biomarkers for several diseases, including pancreatic cancer, due to their roles in cancer development and progression. However, the challenge of utilizing EVs as biomarkers
Externí odkaz:
https://doaj.org/article/7bdbbc46a804416980ed9a1ed4847025
Autor:
Yagna P R Jarajapu, Sugata Hazra, Mark Segal, Sergio Li Calzi, Chandra Jadhao, Kevin Qian, Sayak K Mitter, Mohan K Raizada, Michael E Boulton, Maria B Grant
Publikováno v:
PLoS ONE, Vol 9, Iss 4, p e93965 (2014)
We hypothesized that endothelial progenitor cells derived from individuals with diabetes would exhibit functional defects including inability to respond to hypoxia and altered paracrine/autocrine function that would impair the angiogenic potential of
Externí odkaz:
https://doaj.org/article/e7f09b25d3ea4ccbb11862b45c54bae8
Autor:
Yagna P R Jarajapu, Jun Cai, Yuanqing Yan, Sergio Li Calzi, Jennifer L Kielczewski, Ping Hu, Lynn C Shaw, Sue M Firth, Tailoi Chan-Ling, Michael E Boulton, Robert C Baxter, Maria B Grant
Publikováno v:
PLoS ONE, Vol 7, Iss 7, p e39398 (2012)
Previously, we showed that insulin growth factor (IGF)-1 binding protein-3 (IGFBP-3), independent of IGF-1, reduces pathological angiogenesis in a mouse model of the oxygen-induced retinopathy (OIR). The current study evaluates novel endothelium-depe
Externí odkaz:
https://doaj.org/article/a6bed053f9ec4607a3b13d296454f376
Autor:
Kishore Chittimalli, Jesmin Jahan, Anil Sakamuri, Hope Weyrick, Wink Winkle, Steven Adkins, Stefan W. Vetter, Yagna P. R. Jarajapu
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-15 (2023)
Abstract Aging is associated with chronic systemic inflammation largely due to increased myelopoiesis, which in turn increases risk for vascular disease. We have previously shown evidence for the therapeutic potential of Angiotensin-(1–7) (Ang-(1
Externí odkaz:
https://doaj.org/article/7d3c4b0342b745cc9c76465d213d25f1
Autor:
Yagna P. R. Jarajapu, Alyssa H. Hasty
Publikováno v:
Frontiers in Physiology, Vol 14 (2023)
Externí odkaz:
https://doaj.org/article/429d847d482542368e3e889dbc421e70
Autor:
Kishore Chittimalli, Jesmin Jahan, Anil Sakamuri, Zach L McAdams, Aaron C Ericsson, Yagna P R Jarajapu
Publikováno v:
Clinical Science.
Compromised barrier function of colon epithelium with aging is largely due to gut microbial dysbiosis. Recent studies implicate an important role for angiotensin converting enzymes, ACE and ACE2, angiotensins, and the receptors, AT1 receptor (AT1R) a
Autor:
Yagna P. R. Jarajapu
Publikováno v:
The Renin Angiotensin System in Cardiovascular Disease ISBN: 9783031149511
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c21922282b1fd2768d0b905df05f615c
https://doi.org/10.1007/978-3-031-14952-8_22
https://doi.org/10.1007/978-3-031-14952-8_22
Autor:
Christopher S. Morrow, Darcie L. Moore, Chung-Yang Yeh, Korbyn Dahlquist, Matthew J. Yousefzadeh, John M. Denu, Michaela E Murphy, Chathurika Henpita, Tadataka Tsuji, Reji Babygirija, Josef P. Clark, Yagna P. R. Jarajapu, Timothy W. Rhoads, Alexis Adrian, Heidi H. Pak, Claire E Richardson, Mariah Calubag, Cara L Green, Cristal M. Hill, Rong Yuan, Ankur Kumar, Michelle Sonsalla, Kishore Chittimalli, Christina D. Camell, Vinal Menon, Mark Bouska, Heather A. Simmons, Yun Zhu, Kyoo-A Lee, Dudley W. Lamming, Eric R McGregor, Hua Bai, Judith Simcox, Carolina Soto-Palma, Akilavalli Narasimhan
Publikováno v:
GeroScience
Publikováno v:
GeroScience
Aging increases risk for ischemic vascular diseases. Bone marrow–derived hematopoietic stem/progenitor cells (HSPCs) are known to stimulate vascular regeneration. Activation of either the Mas receptor (MasR) by angiotensin-(1-7) (Ang-(1-7)) or angi
Publikováno v:
Hypertension. 78
The cellular mechanisms underlying enhanced vascular contractility in hypertension are still not fully clear. Recent studies have demonstrated that functional coupling between the large-conductance Ca 2+ -activated K + (BK Ca ) channel in the cell me