Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Yagmur Farsakoglu"'
Autor:
Diego Ulisse Pizzagalli, Irene Latino, Alain Pulfer, Miguel Palomino-Segura, Tommaso Virgilio, Yagmur Farsakoglu, Rolf Krause, Santiago F. Gonzalez
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Neutrophils are amongst the first cells to respond to inflammation and infection. Although they play a key role in limiting the dissemination of pathogens, the study of their dynamic behavior in immune organs remains elusive. In this work, we charact
Externí odkaz:
https://doaj.org/article/ecba12007d95408fac8348c945273155
Autor:
Nikolaos Chatziandreou, Yagmur Farsakoglu, Miguel Palomino-Segura, Rocco D’Antuono, Diego Ulisse Pizzagalli, Federica Sallusto, Veronika Lukacs-Kornek, Mariagrazia Uguccioni, Davide Corti, Shannon J. Turley, Antonio Lanzavecchia, Michael C. Carroll, Santiago F. Gonzalez
Publikováno v:
Cell Reports, Vol 18, Iss 10, Pp 2427-2440 (2017)
The mechanism by which inflammation influences the adaptive response to vaccines is not fully understood. Here, we examine the role of lymph node macrophages (LNMs) in the induction of the cytokine storm triggered by inactivated influenza virus vacci
Externí odkaz:
https://doaj.org/article/934b53f8cf8d45b48b75e2ddcf954ded
Publikováno v:
Cold Spring Harbor perspectives in biology. 13(8)
Immunological memory is a hallmark of adaptive immunity that confers long-lasting protection from reinfections. Memory CD8
Autor:
Dan Chen, Siva Karthik Varanasi, Toshiro Hara, Kacie Traina, Bryan McDonald, Yagmur Farsakoglu, Josh Clanton, Shihao Xu, Thomas H. Mann, Victor Du, H. Kay Chung, Ziyan Xu, Victoria Tripple, Eduardo Casillas, Shixin Ma, Carolyn O’Connor, Qiyuan Yang, Ye Zheng, Tony Hunter, Greg Lemke, Susan M. Kaech
SummaryThe limited efficacy of immunotherapies against glioblastoma illustrates the urgent need to better understand the interactions between the central nervous system and the immune system. Here, we showed that a protective response to αCTLA-4 the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3b3960b3cb167bdea12b699cbc14958b
https://doi.org/10.1101/2022.08.12.502093
https://doi.org/10.1101/2022.08.12.502093
Publikováno v:
European Journal of Immunology
The innate immune response generated against influenza infection is critical for the inhibition of viral dissemination. The trachea contains different types of innate immune cells that protect the respiratory tract from pathogen invasion. Among them,
Autor:
Maria de la Fuente, José Crecente-Campo, Santiago F. Gonzalez, María J. Alonso, Yagmur Farsakoglu, Ana Sara Cordeiro
Publikováno v:
Drug Delivery and Translational Research
The file attached to this record is the author's final peer reviewed version. The Publisher's final version can be found by following the DOI link. In the last few decades, nanotechnology has emerged as an important tool aimed at enhancing the immune
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b9af3c46b7304a9f70741943574de363
https://hdl.handle.net/2086/22580
https://hdl.handle.net/2086/22580
Autor:
Michael Downes, Joseph L. Witztum, Nada A. Abumrad, Bryan McDonald, Antonio Pinto, Susan M. Kaech, Ping-Chih Ho, Maxim N. Shokhirev, Xiaoli Sun, Shihao Xu, Dan Chen, Taha Merghoub, Jun Siong Low, Patricia Rodríguez-Morales, Ronald M. Evans, Victoria Tripple, Brinda Emu, Haiping Wang, Yagmur Farsakoglu, Jedd D. Wolchok, Siva Karthik Varanasi, April Williams, Ziyan Xu, Omkar Chaudhary, Roberta Zappasodi, Wenxi Tang, Guoliang Cui
SummaryT cell metabolic fitness plays a pivotal role in anti-tumor immunity and metabolic deregulation causes T cell dysfunction (i.e., ‘exhaustion’) in cancer. We identify that the scavenger receptor CD36 limits anti-tumor CD8+T cell effector fu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6a4e69180b6e5eb4da9bc3d2a4c4ffdf
https://doi.org/10.1101/2020.09.03.281691
https://doi.org/10.1101/2020.09.03.281691
Autor:
Esen Sefik, Xiaodong Jiang, Christian C. D. Harman, Jun Siong Low, Richard A. Flavell, Yagmur Farsakoglu, Maria Carolina Amezcua Vesely, Susan M. Kaech, Justin A. Shyer, Ruaidhri Jackson, Joseph B. Kelly, Linda S. Cauley
Publikováno v:
The Journal of Experimental Medicine
Low et al. compare the reactivation of memory CD8+ T cells resident in the lung or draining lymph node after a secondary influenza infection and find that memory T cells in the different anatomical locations have unique reactivation mechanics in term
Autor:
Yagmur Farsakoglu, Michael C. Carroll, Olivier Neyrolles, Nikolaos Chatziandreou, Irene Latino, Tommaso Virgilio, Miguel Palomino-Segura, Guojun Wang, Santiago F. Gonzalez, Laurent Perez, Diego Ulisse Pizzagalli, Federica Sallusto, Adolfo García-Sastre, Rocco D’Antuono
Publikováno v:
Nature Microbiology
Nature Microbiology, Nature Publishing Group, 2019, 4 (11), pp.1930-1940. ⟨10.1038/s41564-019-0506-6⟩
Nature microbiology
Nature Microbiology, Nature Publishing Group, 2019, 4 (11), pp.1930-1940. ⟨10.1038/s41564-019-0506-6⟩
Nature microbiology
The initial phase of influenza infection occurs in the upper respiratory tract and the trachea. Yet, little is known about the initial events whereby the immune system recognises the virus and controls viral dissemination. Here, we report that inflam
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e170b49f27007173f57a3929f0fe9c5
https://hal.archives-ouvertes.fr/hal-02346908
https://hal.archives-ouvertes.fr/hal-02346908
Autor:
Taha Merghoub, Michael Downes, Xiaoli Sun, Shihao Xu, Jun Siong Low, April Williams, Yagmur Farsakoglu, Antonio Pinto, Ziyan Xu, Omkar Chaudhary, Ping-Chih Ho, Dan Chen, Wenxi Tang, Bryan McDonald, Roberta Zappasodi, Brinda Emu, Ronald M. Evans, Jedd D. Wolchok, Maxim N. Shokhirev, Susan M. Kaech, Joseph L. Witztum, Haiping Wang, Nada A. Abumrad, Siva Karthik Varanasi, Isabell Schulze, Guoliang Cui, Patricia Rodríguez-Morales, Victoria Tripple
Publikováno v:
Immunity. 54:1561-1577.e7
Summary A common metabolic alteration in the tumor microenvironment (TME) is lipid accumulation, a feature associated with immune dysfunction. Here, we examined how CD8+ tumor infiltrating lymphocytes (TILs) respond to lipids within the TME. We found