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Investigating the effects of Pirfenidone on TGF-β1 stimulated non-SMAD signaling pathways in Dupuytren’s disease -derived fibroblasts

Autor: Chaoming Zhou, Yael Zeldin, Mark E. Baratz, Sandeep Kathju, Latha Satish

Publikováno v: BMC Musculoskeletal Disorders, Vol 20, Iss 1, Pp 1-8 (2019)

Abstract Background Dupuytren’s disease (DD) is a progressive, debilitating condition of the hand that can eventually cause contractures of the affected fingers. Transforming growth factor- β1 (TGF-β1) has been reported to play a key role in DD p

Externí odkaz: https://doaj.org/article/3231b0569c834f4a8ede7121011fa94e

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Investigating the effects of Pirfenidone on TGF-β1 stimulated non-SMAD signaling pathways in Dupuytren's disease -derived fibroblasts

Autor: Sandeep Kathju, Yael Zeldin, Latha Satish, Mark E. Baratz, Chaoming Zhou

Publikováno v: BMC Musculoskeletal Disorders
BMC Musculoskeletal Disorders, Vol 20, Iss 1, Pp 1-8 (2019)

Background Dupuytren’s disease (DD) is a progressive, debilitating condition of the hand that can eventually cause contractures of the affected fingers. Transforming growth factor- β1 (TGF-β1) has been reported to play a key role in DD pathology.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::85bbe3136844e234b84664eede22c0de
https://pubmed.ncbi.nlm.nih.gov/30927912

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