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Autor:
Sebastian Schötz, Adele K. Griepe, Björn B. Goerisch, Sally Kortam, Yael Shammai Vainer, Mathias Dimde, Hanna Koeppe, Stefanie Wedepohl, Elisa Quaas, Katharina Achazi, Avi Schroeder, Rainer Haag
Publikováno v:
Pharmaceuticals, Vol 16, Iss 11, p 1618 (2023)
Rare gastrointestinal stromal tumors (GISTs) are caused by mutations in the KIT and PDGFRA genes. Avapritinib (BLU-285) is a targeted selective inhibitor for mutated KIT and PDGFRA receptors that can be used to treat these tumors. However, there are
Externí odkaz:
https://doaj.org/article/8a1383d23f0b4eabbd602b9ab5892fd4