Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Yael Sagi"'
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss Suppl 1 (2023)
Externí odkaz:
https://doaj.org/article/b1a8527d83654d3bb561af0addf0ff34
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss Suppl 2 (2021)
Externí odkaz:
https://doaj.org/article/2d0a42849c0f4ec28c36ca14a93d3011
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss Suppl 2 (2021)
BackgroundCAR-T therapy has limited efficacy against solid tumors due to low trafficking to the tumor, limited cell expansion in patients, tumor antigen heterogeneity, and an immunosuppressive microenvironment. TTS are fusion proteins that consist of
Publikováno v:
Philos Trans R Soc Lond B Biol Sci
The cross-talk between cancer cells and the stromal microenvironment plays a key role in regulating cancer invasion. Here, we employed an ex vivo invasion model system for exploring the regulation of breast cancer cells infiltration into a variety of
Autor:
Menno C. van Zelm, Yael Sagi, Shoshana Levy, Neta Kela-Madar, Chiung Chi Kuo, Felipe Vences-Catalán, Homer Chen, Jacques J.M. van Dongen
Publikováno v:
Journal of Clinical Immunology, 35(3), 254-263. Springer New York
A homozygous mutation in a splice site of the CD81 gene was identified previously in a patient, as the cause in a case of common variable immune deficiency (CVID). CD19 expression is reduced in mice that lack CD81; however, B cells in this patient la
Publikováno v:
The Journal of Arthroplasty. 29:1072-1075
The purpose of this study was to determine patients' survival after undergoing an early or delayed operation. We retrospectively assessed 1849 files of patients operated for proximal femoral fracture, divided into two diagnostic groups: intracapsular
Autor:
Fa-Xiang Ding, Naama Kessler, Hasmik Sargsyan, Tali Scherf, Eran Noah, Boris Arshava, Fred Naider, Tatsuya Inui, Inbal Ayzenshtat, Jacob Anglister, Einat Schnur, Yael Sagi, Rina Levy
Publikováno v:
Journal of Molecular Biology. 410:778-797
Interaction of CC chemokine receptor 5 (CCR5) with the human immunodeficiency virus type 1 (HIV-1) gp120/CD4 complex involves its amino-terminal domain (Nt-CCR5) and requires sulfation of two to four tyrosine residues in Nt-CCR5. The conformation of
Autor:
Rina Barak, Orna Liarzi, Monica Dines, Michael Eisenbach, Vered Bronner, Alla Shainskaya, Yael Sagi
Publikováno v:
Molecular Microbiology. 76:932-943
Summary The ability of CheY, the response regulator of bacterial chemotaxis, to generate clockwise rotation is regulated by two covalent modifications – phosphorylation and acetylation. While the function and signal propagation of the former are wi
Autor:
Noreen R. Francis, Eyal Shimoni, Michael Eisenbach, Yael Sagi, Dror Noy, Gary Cecchini, Rose M. Johnstone, Yaacov Davidov, Galit N Cohen-Ben-Lulu, Krishna Prasad
Publikováno v:
The EMBO Journal. 27:1134-1144
The mechanism of function of the bacterial flagellar switch, which determines the direction of flagellar rotation and is essential for chemotaxis, has remained an enigma for many years. Here we show that the switch complex associates with the membran
Publikováno v:
Journal of Biological Chemistry. 278:25867-25871
In bacteria, the chemotactic signal is greatly amplified between the chemotaxis receptors and the flagellar motor. In Escherichia coli, part of this amplification occurs at the flagellar switch. However, it is not known whether the amplification resu