Zobrazeno 1 - 10
of 48
pro vyhledávání: '"Yael Nisgav"'
Autor:
Livnat, Yehonatan Weinberger, Ivan Budnik, Yael Nisgav, Dahlia Palevski, Gil Ben-David, José A. Fernández, Shany Nivinsky Margalit, Sarina Levy-Mendelovich, Gili Kenet, Dov Weinberger, John H. Griffin, Tami
Publikováno v:
International Journal of Molecular Sciences; Volume 24; Issue 13; Pages: 10642
3K3A-Activated Protein C (APC) is a recombinant variant of the physiological anticoagulant APC with cytoprotective properties and reduced bleeding risks. We studied the potential use of 3K3A-APC as a multi-target therapeutic option for choroidal neov
Autor:
Tami Livnat, Yehonatan Weinberger, José A. Fernández, Alaa Bashir, Gil Ben-David, Dahlia Palevski, Sarina Levy-Mendelovich, Gili Kenet, Ivan Budnik, Yael Nisgav, John H. Griffin, Dov Weinberger
Publikováno v:
Biomolecules, Vol 11, Iss 3, p 358 (2021)
The activated protein C (APC) ability to inhibit choroidal neovascularization (CNV) growth and leakage was recently shown in a murine model. A modified APC, 3K3A-APC, was designed to reduce anticoagulant activity while maintaining full cytoprotective
Externí odkaz:
https://doaj.org/article/257408fbd8ea498eaece922f8cc88963
Autor:
Dahlia Palevski, Gil Ben-David, Yehonatan Weinberger, Rabeei Haj Daood, José A. Fernández, Ivan Budnik, Sarina Levy-Mendelovich, Gili Kenet, Yael Nisgav, Dov Weinberger, John H. Griffin, Tami Livnat
Publikováno v:
International Journal of Molecular Sciences; Volume 23; Issue 22; Pages: 14196
3K3A-Activated Protein C (APC) is a recombinant variant of the physiological anticoagulant APC with pleiotropic cytoprotective properties albeit without the bleeding risks. The anti-inflammatory activities of 3K3A-APC were demonstrated in multiple pr
Publikováno v:
Cornea. 39:1027-1030
Purpose To evaluate whether punching Descemet membrane endothelial keratoplasty (DMEK) corneal grafts onto a contact lens scaffold reduces endothelial cell loss at the graft margin in comparison to punching the graft directly onto the donor stroma. M
Autor:
Eitan Livny, Tami Livnat, Ruti Sella, Orly Gal-Or, Irit Bahar, Maya Eiger-Moscovich, Yael Nisgav
Publikováno v:
Ophthalmic Research. 62:116-122
Aim: To compare the efficacy of aflibercept (Eylea®), a potent antivascular endothelial growth factor (VEGF) agent, with betamethasone (Celestone®) and placebo for the treatment of formed corneal neovascularization in a rabbit model. Methods: A cen
Autor:
Yael Nisgav, Alon Zahavi, Tami Livnat, Idit Dan‐Brezis, Rita Ehrlich, Dov Weinberger, Mor Dahbash, Ruth Axer-Siegel
Publikováno v:
Acta Ophthalmologica. 98
PURPOSE To evaluate and correlate levels of various proteins involved in coagulation, inflammation and angiogenesis processes in the vitreous of patients with different vitreoretinal pathologies. METHODS Vitreous samples were collected from patients
Autor:
Yael Nisgav, Dan D. Gaton, Opher Kinrot, Tilda Barliya, Mor Dahbash, Dov Weinberger, Elite Bor-Shavit, Tami Livnat
Publikováno v:
Current Eye Research. 42:1545-1551
Purpose This study aims to evaluate and standardize the reliability of a mobile laser indirect ophthalmoscope in the induction of choroidal neovascularization (CNV) in a mouse model. Materials & methods A diode laser indirect ophthalmoscope was used
Autor:
Iftach Yassur, Katia Pozyuchenko, Ekaterina Lazdon, Yael Nisgav, Hadas Stiebel-Kalish, Dan Frenkel, Judith Brody, Karny Shouchane-Blum
Publikováno v:
Journal of neuroscience methods. 331
Background Numerous disorders affecting the optic nerve require histological examination of whole length optic nerves and chiasm. Most methods employed to study the histopathology of the optic nerves in animal models of human diseases involve resecti
Autor:
Iris Deitch, Dov Weinberger, Ruti Sella, Rima Dardik, Tami Livnat, Yehonatan Weinberger, Ivan Budnik, Mor Dahbash, Gili Kenet, Yael Nisgav
Publikováno v:
Experimental eye research. 186
Activated protein C (APC) exerts diverse cell signaling pathways which results in multiple distinct cytoprotective actions. These include anti-apoptotic and anti-inflammatory activities and stabilization of endothelial and epithelial barriers. We stu
Autor:
Mor Dahbash, Tami Livnat, Ruti Sella, Nataly Tarasenko, Ada Rephaeli, Yael Nisgav, Elinor Megiddo-Barnir, Dov Weinberger
Publikováno v:
International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 20, Iss 3, p 714 (2019)
Volume 20
Issue 3
International Journal of Molecular Sciences, Vol 20, Iss 3, p 714 (2019)
Volume 20
Issue 3
Choroidal neovascularization (CNV) is a complication of age-related macular degeneration and a major contributing factor to vision loss. In this paper, we show that in a mouse model of laser-induced CNV, systemic administration of Butyroyloxymethyl-d