Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Yael Gore"'
Autor:
Debby Reuveni, Yael Gore, Patrick S. C. Leung, Yael Lichter, Itay Moshkovits, Ayelet Kaminitz, Eli Brazowski, Eric Lefebvre, Pamela Vig, Chen Varol, Zamir Halpern, Oren Shibolet, Merrill Eric Gershwin, Ehud Zigmond
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
The therapy of primary biliary cholangitis (PBC) has lagged behind other autoimmune diseases despite significant improvements in our understanding of both immunological and molecular events that lead to loss of tolerance to the E2 component of pyruva
Externí odkaz:
https://doaj.org/article/7c790b433c574dfab4927f871cf92829
Autor:
Zamir Halpern, M. E. Gershwin, Itay Moshkovits, Yael Gore, Chen Varol, Yael Lichter, Oren Shibolet, Debby Reuveni, Ayelet Kaminitz, Pamela Vig, Eli Brazowski, Ehud Zigmond, Patrick S.C. Leung, Eric Lefebvre
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
Frontiers in Immunology
Frontiers in Immunology
The therapy of primary biliary cholangitis (PBC) has lagged behind other autoimmune diseases despite significant improvements in our understanding of both immunological and molecular events that lead to loss of tolerance to the E2 component of pyruva
Autor:
Yael Gore, Maya Gordin, Melania Tesio, Frida Lantner, Lin Leng, Idit Shachar, Richard Bucala, Sivan Cohen
Publikováno v:
The Journal of Immunology. 185:2020-2031
The signals regulating the survival of mature splenic B cells have become a major focus in recent studies of B cell immunology. Durable B cell persistence in the periphery is dependent on survival signals that are transduced by cell surface receptors
Publikováno v:
Molecular Biology of the Cell
Id2 is a negative regulator of B cell differentiation. Its expression was found to depend on Myc–Max–Mad transcriptional complexes. Here, we show that Mad3 expression levels that are elevated in immature B cells are actively involved in inducing
Autor:
Yael Gore, Guy Cinamon, Ronen Alon, Idit Shachar, Gera Goverse, Raanan Margalit, Valentin Grabovsky, Reina E. Mebius, Sara W. Feigelson, Doron Melamed, Eugenia Manevich-Mendelson, David R. Critchley, Susan J. Monkley
Publikováno v:
Manevich-Mendelson, E, Grabovsky, V, Feigelson, S W, Cinamon, G, Gore, Y, Goverse, G, Monkley, S J, Margalit, R, Melamed, D, Mebius, R E, Critchley, D R, Shachar, I & Alon, R 2010, ' Talin1 is required for integrin-dependent B lymphocyte homing to lymph nodes and the bone marrow but not for follicular B-cell maturation in the spleen ', Blood, vol. 116, no. 26, pp. 5907-5918 . https://doi.org/10.1182/blood-2010-06-293506
Blood, 116(26), 5907-5918. American Society of Hematology
Blood, 116(26), 5907-5918. American Society of Hematology
Talin1 is a key integrin coactivator. We investigated the roles of this cytoskeletal adaptor and its target integrins in B-cell lymphogenesis, differentiation, migration, and function. Using CD19 Cre-mediated depletion of talin1 selectively in B cell
Autor:
Utako Kaneyuki, Richard Bucala, Idit Shachar, Diana Starlets, Yael Gore, Shirly Becker-Herman, Lin Leng, Nitsan Maharshak
Publikováno v:
Journal of Biological Chemistry. 283:2784-2792
Macrophage migration inhibitory factor (MIF) is an upstream activator of innate immunity that regulates subsequent adaptive responses. It was previously shown that in macrophages, MIF binds to a complex of CD74 and CD44, resulting in initiation of a
Autor:
Lin Leng, Yael Gore, Yossy Machluf, Rivka Dikstein, Diana Starlets, Richard Bucala, Ayala Yamit-Hezi, Moshe Oren, Liat Flaishon, Frida Lantner, Idit Shachar
Publikováno v:
Blood. 110:4303-4311
Most mature follicular B cells circulate within the periphery in a quiescent state, without actively contributing to an acute immune response. Lasting B-cell persistence in the periphery is dependent on survival signals that are transduced by cell su
Autor:
Diana Starlets, Lev Shvidel, Alain Berrebi, Nurit Harpaz, Yael Gore, Richard Bucala, Michal Haran, Frida Lantner, Idit Shachar, Lin Leng, David M. Goldenberg, Inbal Binsky
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 104(33)
Chronic lymphocytic leukemia (CLL) is a malignant disease of small mature lymphocytes. Previous studies have shown that CLL B lymphocytes express relatively large amounts of CD74 mRNA relative to normal B cells. In the present study, we analyzed the
Autor:
Lev Shvidel, Idit Shachar, Inbal Binsky, Shirly Becker-Herman, Diana Starlets, Alain Berrebi, Michal Haran, Nurit Harpaz, Yael Gore
Publikováno v:
Blood. 107(12)
CD74 is an integral membrane protein that was thought to function mainly as an MHC class II chaperone. However, CD74 was recently shown to have a role as an accessory-signaling molecule. Our studies demonstrated that CD74 regulates B-cell differentia