Zobrazeno 1 - 10
of 107
pro vyhledávání: '"Yael, Mardor"'
Autor:
Valeria Cuccarini, Filippo Savoldi, Yael Mardor, David Last, Serena Pellegatta, Federica Mazzi, Maria Grazia Bruzzone, Elena Anghileri, Bianca Pollo, Luisa Maddaloni, Camilla Russo, Elisa Bocchi, Valentina Pinzi, Marica Eoli, Domenico Aquino
Publikováno v:
Frontiers in Neurology, Vol 15 (2024)
IntroductionAssessing the treatment response of glioblastoma multiforme during immunotherapy (IT) is an open issue. Treatment response assessment maps (TRAMs) might help distinguish true tumor progression (TTP) and pseudoprogression (PsP) in this set
Externí odkaz:
https://doaj.org/article/baa3d75dcf664b6aa2f6f45e7e2003f6
Autor:
Itzik Cooper, David Last, Orly Ravid, Daniel Rand, Erez Matsree, Liora Omesi, Chen Shemesh, Meir Liberman, Leor Zach, Orit Furman, Dianne Daniels, Sigal Liraz-Zaltsman, Yael Mardor, Shirley Sharabi
Publikováno v:
Fluids and Barriers of the CNS, Vol 20, Iss 1, Pp 1-12 (2023)
Abstract Background Pharmacological treatment of CNS diseases is limited due to the presence of the blood-brain barrier (BBB). Recent years showed significant advancement in the field of CNS drug delivery enablers, with technologies such as MR-guided
Externí odkaz:
https://doaj.org/article/bb56778727ba447385070c29cbca3022
Autor:
Avraham Abutbul, Helena Mumblat, Yaara Porat, Nehemya Friedman, Nofar Atari, Shirley Sharabi, Ahmad Nama, Waseem Mugahed, Asa Kessler, Yotam Kolben, Reuben Ruby Shamir, Doron Manzur, Ori Farber, Liora Bosch, Gitit Lavy-Shahaf, Eyal Dor-On, Adi Haber, Moshe Giladi, Uri Weinberg, Yoram Palti, Yael Mardor, Michal Mandelboim
Publikováno v:
Frontiers in Microbiology, Vol 14 (2023)
Coronaviruses are the causative agents of several recent outbreaks, including the COVID-19 pandemic. One therapeutic approach is blocking viral binding to the host receptor. As binding largely depends on electrostatic interactions, we hypothesized po
Externí odkaz:
https://doaj.org/article/24eca6fa1c1b4314baa96b005a1eb007
Autor:
Michal Weitman, Arik Eisenkraft, Zeev TaShma, Igor Makarovsky, David Last, Dianne Daniels, David Guez, Ran Shneor, Yael Mardor, Abraham Nudelman, Amir Krivoy
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-14 (2022)
Abstract Organophosphates (OPs) are inhibitors of acetylcholinesterase and have deleterious effects on the central nervous system. Clinical manifestations of OP poisoning include convulsions, which represent an underlying toxic neuro-pathological pro
Externí odkaz:
https://doaj.org/article/4b92c05d70194c7eade5e4a19ed444c3
Autor:
Shirley Sharabi, Yael Bresler, Orly Ravid, Chen Shemesh, Dana Atrakchi, Michal Schnaider-Beeri, Fabien Gosselet, Lucie Dehouck, David Last, David Guez, Dianne Daniels, Yael Mardor, Itzik Cooper
Publikováno v:
Drug Delivery, Vol 26, Iss 1, Pp 459-469 (2019)
The blood–brain barrier (BBB) is limiting transcellular and paracellular movement of molecules and cells, controls molecular traffic, and keeps out toxins. However, this protective function is the major hurdle for treating brain diseases such as br
Externí odkaz:
https://doaj.org/article/ae3466cb4fa04f828c480042ace88ee9
Autor:
Adi Tzameret, Hadas Ketter-Katz, Victoria Edelshtain, Ifat Sher, Enav Corem-Salkmon, Itay Levy, David Last, David Guez, Yael Mardor, Shlomo Margel, Ygal Rotenstrich
Publikováno v:
Journal of Nanobiotechnology, Vol 17, Iss 1, Pp 1-11 (2019)
Abstract Background Retinal degeneration diseases affect millions of patients worldwide and lead to incurable vision loss. These diseases are caused by pathologies in the retina and underlying choroid, located in the back of the eye. One of the major
Externí odkaz:
https://doaj.org/article/5ca1db1bd22f49b0940fcdcf3b3a8033
Publikováno v:
Neurology Asia. 27:353-362
Background: The purpose of this study is to explore changes in blood-brain barrier (BBB) function and volumetry associated with Parkinson’s disease (PD) levodopa-induced-dyskinesia (LID). Methods: Twenty-six PD patients [matched pairs, 13 with LID
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c331585289e516d7c58838647b8972c0
https://doi.org/10.54029/2022ycu
https://doi.org/10.54029/2022ycu
Autor:
Shirley Sharabi, David Last, Dianne Daniels, Ido Didi Fabian, Dana Atrakchi, Yael Bresler, Sigal Liraz-Zaltsman, Itzik Cooper, Yael Mardor
Publikováno v:
Pharmaceutics, Vol 13, Iss 2, p 169 (2021)
The blood–brain barrier (BBB) is a major hurdle for the treatment of central nervous system disorders, limiting passage of both small and large therapeutic agents from the blood stream into the brain. Thus, means for inducing BBB disruption (BBBd)
Externí odkaz:
https://doaj.org/article/26a9943464464add9e4e79251dde1c53
Autor:
John H Sampson, Achal Singh Achrol, Manish K Aghi, Krystof Bankiewicz, Martin Bexon, Steven Brem, Andrew Brenner, Chandtip Chandhasin, Sajeel Chowdhary, Melissa Coello, Benjamin M Ellingson, John R Floyd, Seunggu Han, Santosh Kesari, Yael Mardor, Fahar Merchant, Nina Merchant, Dina Randazzo, Michael Vogelbaum, Frank Vrionis, Eva Wembacher-Schroeder, Miroslaw Zabek, Nicholas Butowski
Publikováno v:
Neuro-Oncology.
BackgroundMDNA55 is an interleukin 4 receptor (IL4R)-targeting toxin in development for recurrent GBM, a universally fatal disease. IL4R is overexpressed in GBM as well as cells of the tumor microenvironment. High expression of IL4R is associated wit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f3a7afdb27ff9eeb46115fd9242b0cd5
https://doi.org/10.1093/neuonc/noac285
https://doi.org/10.1093/neuonc/noac285
Autor:
Efrat Shavit-Stein, Ehud Sheinberg, Valery Golderman, Shirley Sharabi, Anton Wohl, Shany Guly Gofrit, Zion Zivli, Natalia Shelestovich, David Last, David Guez, Dianne Daniels, Orna Gera, Kate Feingold, Zeev Itsekson-Hayosh, Nurit Rosenberg, Ilia Tamarin, Amir Dori, Nicola Maggio, Yael Mardor, Joab Chapman, Sagi Harnof
Publikováno v:
Frontiers in Neurology, Vol 9 (2018)
Data from human biopsies, in-vitro and in-vivo models, strongly supports the role of thrombin, and its protease-activated receptor (PAR1) in the pathology and progression of glioblastoma (GBM), a high-grade glial tumor. Activation of PAR1 by thrombin
Externí odkaz:
https://doaj.org/article/e3778abfadb74a178594337d8298298d