Zobrazeno 1 - 10
of 95
pro vyhledávání: '"Yadav, Sapkota"'
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-12 (2024)
Abstract Nilotinib is a highly effective treatment for chronic myeloid leukemia but has been consistently associated with the development of nilotinib-induced arterial disease (NAD) in a subset of patients. To date, which cell types mediate this effe
Externí odkaz:
https://doaj.org/article/54bcecbe99f24cacb8e86b5ec53ec481
Autor:
Donald Rees, D. Matthew Gianferante, Jung Kim, Theodora Stavrou, Gregory Reaman, Yadav Sapkota, M. Monica Gramatges, Lindsay M. Morton, Melissa M. Hudson, Gregory T. Armstrong, Neal D. Freedman, Wen-Yi Huang, W. Ryan Diver, Adriana Lori, Wen Luo, Belynda D. Hicks, Jia Liu, Amy A. Hutchinson, Alisa M. Goldstein, Lisa Mirabello
Publikováno v:
Frontiers in Oncology, Vol 14 (2024)
BackgroundMedulloblastoma is the most common malignant brain tumor in children. Most cases are sporadic, but well characterized germline alterations in APC, ELP1, GPR161, PTCH1, SUFU, and TP53 predispose to medulloblastoma. However, knowledge about p
Externí odkaz:
https://doaj.org/article/f19e939d15a6499c95303648c3dec928
Autor:
K. Ashley Fetterman, Malorie Blancard, Davi M. Lyra-Leite, Carlos G. Vanoye, Hananeh Fonoudi, Mariam Jouni, Jean-Marc L. DeKeyser, Brian Lenny, Yadav Sapkota, Alfred L. George, Jr., Paul W. Burridge
Publikováno v:
Cell Reports, Vol 43, Iss 5, Pp 114160- (2024)
Summary: Human induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CMs) recapitulate numerous disease and drug response phenotypes, but cell immaturity may limit their accuracy and fidelity as a model system. Cell culture medium modification
Externí odkaz:
https://doaj.org/article/df419155f7fa4cacb87f83b0c98d9bc2
Autor:
Aron Onerup, Sedigheh Mirzaei S., Shalini Bhatia, Megan E. Ware, Lenat Joffe, Lucie M. Turcotte, Chelsea G. Goodenough, Yadav Sapkota, Stephanie B. Dixon, Matthew D. Wogksch, Matthew J. Ehrhardt, Gregory T. Armstrong, Melissa M. Hudson, Kirsten K. Ness
Publikováno v:
Cancer Reports, Vol 7, Iss 1, Pp n/a-n/a (2024)
Abstract Background Lifestyle is associated with meningioma risk in the general population. Aims We assessed longitudinal associations between lifestyle‐associated factors and subsequent meningiomas in childhood cancer survivors. Methods and result
Externí odkaz:
https://doaj.org/article/3648d9a6d71b4fafa382a1c7dad37e95
Autor:
Donghao Lu, Yadav Sapkota, Unnur A. Valdimarsdóttir, Karestan C. Koenen, Nan Li, Wendy M. Leisenring, Todd Gibson, Carmen L. Wilson, Leslie L. Robison, Melissa M. Hudson, Gregory T. Armstrong, Kevin R. Krull, Yutaka Yasui, Smita Bhatia, Christopher J. Recklitis
Publikováno v:
Translational Psychiatry, Vol 12, Iss 1, Pp 1-10 (2022)
Abstract Genetic influence shapes who develops posttraumatic stress disorder (PTSD) after traumatic events. However, the genetic variants identified for PTSD may in fact be associated with traumatic exposures (e.g., interpersonal violence), which app
Externí odkaz:
https://doaj.org/article/6dabfc66c23d44cea0e35ca23d192f6f
Autor:
Xuexia Wang, Purnima Singh, Liting Zhou, Noha Sharafeldin, Wendy Landier, Lindsey Hageman, Paul Burridge, Yutaka Yasui, Yadav Sapkota, Javier G. Blanco, Kevin C. Oeffinger, Melissa M. Hudson, Eric J. Chow, Saro H. Armenian, Joseph P. Neglia, A. Kim Ritchey, Douglas S. Hawkins, Jill P. Ginsberg, Leslie L. Robison, Gregory T. Armstrong, Smita Bhatia
Publikováno v:
Journal of Clinical Oncology. 41:1758-1769
PURPOSE Interindividual variability in the dose-dependent association between anthracyclines and cardiomyopathy suggests a modifying role of genetic susceptibility. Few previous studies have examined gene-anthracycline interactions. We addressed this
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8b0274c69067091dcebaaae2f0e73189
https://doi.org/10.1200/jco.22.01527
https://doi.org/10.1200/jco.22.01527
Publikováno v:
Soil Science Society of America Journal. 87:390-403
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::de35b5b3700ee8bb095daeb3ec6654a2
https://doi.org/10.1002/saj2.20515
https://doi.org/10.1002/saj2.20515
Autor:
Aurélien Macé, Marcus A. Tuke, Patrick Deelen, Kati Kristiansson, Hannele Mattsson, Margit Nõukas, Yadav Sapkota, Ursula Schick, Eleonora Porcu, Sina Rüeger, Aaron F. McDaid, David Porteous, Thomas W. Winkler, Erika Salvi, Nick Shrine, Xueping Liu, Wei Q. Ang, Weihua Zhang, Mary F. Feitosa, Cristina Venturini, Peter J. van der Most, Anders Rosengren, Andrew R. Wood, Robin N. Beaumont, Samuel E. Jones, Katherine S. Ruth, Hanieh Yaghootkar, Jessica Tyrrell, Aki S. Havulinna, Harmen Boers, Reedik Mägi, Jennifer Kriebel, Martina Müller-Nurasyid, Markus Perola, Markku Nieminen, Marja-Liisa Lokki, Mika Kähönen, Jorma S. Viikari, Frank Geller, Jari Lahti, Aarno Palotie, Päivikki Koponen, Annamari Lundqvist, Harri Rissanen, Erwin P. Bottinger, Saima Afaq, Mary K. Wojczynski, Petra Lenzini, Ilja M. Nolte, Thomas Sparsø, Nicole Schupf, Kaare Christensen, Thomas T. Perls, Anne B. Newman, Thomas Werge, Harold Snieder, Timothy D. Spector, John C. Chambers, Seppo Koskinen, Mads Melbye, Olli T. Raitakari, Terho Lehtimäki, Martin D. Tobin, Louise V. Wain, Juha Sinisalo, Annette Peters, Thomas Meitinger, Nicholas G. Martin, Naomi R. Wray, Grant W. Montgomery, Sarah E. Medland, Morris A. Swertz, Erkki Vartiainen, Katja Borodulin, Satu Männistö, Anna Murray, Murielle Bochud, Sébastien Jacquemont, Fernando Rivadeneira, Thomas F. Hansen, Albertine J. Oldehinkel, Massimo Mangino, Michael A. Province, Panos Deloukas, Jaspal S. Kooner, Rachel M. Freathy, Craig Pennell, Bjarke Feenstra, David P. Strachan, Guillaume Lettre, Joel Hirschhorn, Daniele Cusi, Iris M. Heid, Caroline Hayward, Katrin Männik, Jacques S. Beckmann, Ruth J. F. Loos, Dale R. Nyholt, Andres Metspalu, Johan G. Eriksson, Michael N. Weedon, Veikko Salomaa, Lude Franke, Alexandre Reymond, Timothy M. Frayling, Zoltán Kutalik
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-11 (2017)
Individual SNPs have small effects on anthropometric traits, yet the impact of CNVs has remained largely unknown. Here, Kutalik and co-workers perform a large-scale genome-wide meta-analysis of structural variation and find rare CNVs associated with
Externí odkaz:
https://doaj.org/article/6a8ab1d070da4fdd8e0c0617397195b3
Autor:
Yadav Sapkota, Valgerdur Steinthorsdottir, Andrew P. Morris, Amelie Fassbender, Nilufer Rahmioglu, Immaculata De Vivo, Julie E. Buring, Futao Zhang, Todd L. Edwards, Sarah Jones, Dorien O, Daniëlle Peterse, Kathryn M. Rexrode, Paul M. Ridker, Andrew J. Schork, Stuart MacGregor, Nicholas G. Martin, Christian M. Becker, Sosuke Adachi, Kosuke Yoshihara, Takayuki Enomoto, Atsushi Takahashi, Yoichiro Kamatani, Koichi Matsuda, Michiaki Kubo, Gudmar Thorleifsson, Reynir T. Geirsson, Unnur Thorsteinsdottir, Leanne M. Wallace, iPSYCH-SSI-Broad Group, Jian Yang, Digna R. Velez Edwards, Mette Nyegaard, Siew-Kee Low, Krina T. Zondervan, Stacey A. Missmer, Thomas D'Hooghe, Grant W. Montgomery, Daniel I. Chasman, Kari Stefansson, Joyce Y. Tung, Dale R. Nyholt
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-12 (2017)
Endometriosis is a major cause of infertility. Molecular mechanisms underlying the disease involve genetic and environmental risk factors. In a meta-analysis of eleven GWA studies, Sapkota and colleagues identify five novel risk loci, implicating ste
Externí odkaz:
https://doaj.org/article/01ad40bb5e464263812572052ae10cf6
Autor:
Yadav Sapkota, Weiyu Qiu, Stephanie B. Dixon, Carmen L. Wilson, Zhaoming Wang, Jinghui Zhang, Wendy Leisenring, Eric J. Chow, Smita Bhatia, Gregory T. Armstrong, Leslie L. Robison, Melissa M. Hudson, Angela Delaney, Yutaka Yasui
Publikováno v:
Nature Medicine. 28:1590-1598
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e6c5951d490c70ddd1dbf49a7498df84
https://doi.org/10.1038/s41591-022-01902-3
https://doi.org/10.1038/s41591-022-01902-3