Oncogenic deubiquitination controls tyrosine kinase signaling and therapy response in acute lymphoblastic leukemia.

Autor: Jin Q; Department of Biochemistry and Molecular Genetics, Northwestern University, Chicago, IL, USA.; Simpson Querrey Center for Epigenetics, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA., Gutierrez Diaz B; Department of Biochemistry and Molecular Genetics, Northwestern University, Chicago, IL, USA.; Simpson Querrey Center for Epigenetics, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA., Pieters T; Department of Biomolecular Medicine, Ghent University, Ghent, Belgium.; Center for Medical Genetics, Ghent University and University Hospital, Ghent, Belgium.; Cancer Research Institute Ghent (CRIG), Ghent, Belgium., Zhou Y; Department of Biochemistry and Molecular Genetics, Northwestern University, Chicago, IL, USA.; Simpson Querrey Center for Epigenetics, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA., Narang S; Department of Pathology, New York University School of Medicine, New York, NY, USA.; Laura and Isaac Perlmutter Cancer Center, New York University School of Medicine, New York, NY, USA.; Applied Bioinformatics Laboratories, Office of Science and Research, New York University School of Medicine, New York, NY, USA., Fijalkwoski I; Department of Biomolecular Medicine, Ghent University, Ghent, Belgium.; Center for Medical Genetics, Ghent University and University Hospital, Ghent, Belgium.; Cancer Research Institute Ghent (CRIG), Ghent, Belgium., Borin C; Department of Biomolecular Medicine, Ghent University, Ghent, Belgium.; Center for Medical Genetics, Ghent University and University Hospital, Ghent, Belgium.; Cancer Research Institute Ghent (CRIG), Ghent, Belgium., Van Laere J; Department of Biomolecular Medicine, Ghent University, Ghent, Belgium.; Center for Medical Genetics, Ghent University and University Hospital, Ghent, Belgium., Payton M; Division of Experimental Hematology, St. Jude Children's Research Hospital, Memphis, TN, USA., Cho BK; Proteomics Center of Excellence, Northwestern University, Evanston, IL, USA., Han C; Department of Biochemistry and Molecular Genetics, Northwestern University, Chicago, IL, USA.; Simpson Querrey Center for Epigenetics, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA., Sun L; Department of Biochemistry and Molecular Genetics, Northwestern University, Chicago, IL, USA.; Simpson Querrey Center for Epigenetics, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA., Serafin V; Oncohematology Laboratory, Department of Women's and Children's Health, University of Padova, Padova, Italy.; Department of Surgery Oncology and Gastroenterology, Oncology and Immunology Section, University of Padova, Padova, Italy., Yacu G; Department of Biochemistry and Molecular Genetics, Northwestern University, Chicago, IL, USA., Von Loocke W; Department of Pathology, New York University School of Medicine, New York, NY, USA., Basso G; Oncohematology Laboratory, Department of Women's and Children's Health, University of Padova, Padova, Italy.; Department of Surgery Oncology and Gastroenterology, Oncology and Immunology Section, University of Padova, Padova, Italy., Veltri G; Oncohematology Laboratory, Department of Women's and Children's Health, University of Padova, Padova, Italy., Dreveny I; School of Pharmacy, University of Nottingham, Nottingham NG7 2RD, UK., Ben-Sahra I; Department of Biochemistry and Molecular Genetics, Northwestern University, Chicago, IL, USA.; Simpson Querrey Center for Epigenetics, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA., Goo YA; Department of Biochemistry and Molecular Genetics, Northwestern University, Chicago, IL, USA.; Simpson Querrey Center for Epigenetics, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA.; Proteomics Center of Excellence, Northwestern University, Evanston, IL, USA., Safgren SL; Division of Experimental Pathology and Laboratory Medicine, Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN, USA., Tsai YC; University Children's Hospital, Division of Pediatric Oncology, University of Zurich, Zurich, Switzerland., Bornhauser B; University Children's Hospital, Division of Pediatric Oncology, University of Zurich, Zurich, Switzerland., Suraneni PK; Department of Cell and Developmental Biology, Northwestern University, Chicago, IL, USA., Gaspar-Maia A; Division of Experimental Pathology and Laboratory Medicine, Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN, USA., Kandela I; Center for Developmental Therapeutics, Northwestern University, Evanston, IL, USA., Van Vlierberghe P; Department of Biomolecular Medicine, Ghent University, Ghent, Belgium.; Center for Medical Genetics, Ghent University and University Hospital, Ghent, Belgium.; Cancer Research Institute Ghent (CRIG), Ghent, Belgium., Crispino JD; Division of Experimental Hematology, St. Jude Children's Research Hospital, Memphis, TN, USA., Tsirigos A; Department of Pathology, New York University School of Medicine, New York, NY, USA.; Laura and Isaac Perlmutter Cancer Center, New York University School of Medicine, New York, NY, USA.; Applied Bioinformatics Laboratories, Office of Science and Research, New York University School of Medicine, New York, NY, USA., Ntziachristos P; Department of Biomolecular Medicine, Ghent University, Ghent, Belgium.; Center for Medical Genetics, Ghent University and University Hospital, Ghent, Belgium.; Cancer Research Institute Ghent (CRIG), Ghent, Belgium.

Publikováno v: Science advances [Sci Adv] 2022 Dec 09; Vol. 8 (49), pp. eabq8437. Date of Electronic Publication: 2022 Dec 09.

Posttranslational Regulation of the Exon Skipping Machinery Controls Aberrant Splicing in Leukemia.

Autor: Zhou Y; Department of Biochemistry and Molecular Genetics, Northwestern University, Chicago, Illinois.; Simpson Querrey Institute for Epigenetics, Northwestern University Feinberg School of Medicine, Chicago, Illinois., Han C; Department of Biochemistry and Molecular Genetics, Northwestern University, Chicago, Illinois.; Simpson Querrey Institute for Epigenetics, Northwestern University Feinberg School of Medicine, Chicago, Illinois., Wang E; Department of Pathology and Laura & Isaac Perlmutter Cancer Center, New York University School of Medicine, New York, New York., Lorch AH; Department of Biochemistry and Molecular Genetics, Northwestern University, Chicago, Illinois.; Simpson Querrey Institute for Epigenetics, Northwestern University Feinberg School of Medicine, Chicago, Illinois., Serafin V; Oncohematology Laboratory, Department of Women's and Children's Health, University of Padova, Padova, Italy., Cho BK; Proteomics Center of Excellence, Northwestern University, Evanston, Illinois., Gutierrez Diaz BT; Department of Biochemistry and Molecular Genetics, Northwestern University, Chicago, Illinois.; Simpson Querrey Institute for Epigenetics, Northwestern University Feinberg School of Medicine, Chicago, Illinois., Calvo J; Team Niche and Cancer in hematopoiesis, CEA, Fontenay-aux-Roses, France.; Laboratory of Hematopoietic Stem Cells and Leukemia/Service Stem Cells and Radiation/iRCM/JACOB/DRF, CEA, Fontenay-aux-Roses, France., Fang C; Department of Biochemistry and Molecular Genetics, Northwestern University, Chicago, Illinois.; Simpson Querrey Institute for Epigenetics, Northwestern University Feinberg School of Medicine, Chicago, Illinois.; Medical Scientist Training Program, Northwestern University Feinberg School of Medicine, Chicago, Illinois., Khodadadi-Jamayran A; Applied Bioinformatics Laboratories, Office of Science and Research, New York University School of Medicine, New York, New York., Tabaglio T; Institute of Molecular and Cell Biology, Agency for Science, Technology and Research, Singapore.; Department of Biochemistry, Yong Loo Lin School of Medicine, National University of Singapore, Singapore., Marier C; Genome Technology Center, New York University School of Medicine, New York, New York., Kuchmiy A; Cancer Research Institute Ghent (CRIG), Ghent, Belgium.; Department of Diagnostic Sciences, Ghent University, Ghent, Belgium., Sun L; Department of Biochemistry and Molecular Genetics, Northwestern University, Chicago, Illinois.; Simpson Querrey Institute for Epigenetics, Northwestern University Feinberg School of Medicine, Chicago, Illinois., Yacu G; Department of Biochemistry and Molecular Genetics, Northwestern University, Chicago, Illinois.; Simpson Querrey Institute for Epigenetics, Northwestern University Feinberg School of Medicine, Chicago, Illinois., Filip SK; Proteomics Center of Excellence, Northwestern University, Evanston, Illinois., Jin Q; Department of Biochemistry and Molecular Genetics, Northwestern University, Chicago, Illinois.; Simpson Querrey Institute for Epigenetics, Northwestern University Feinberg School of Medicine, Chicago, Illinois., Takahashi YH; Department of Biochemistry and Molecular Genetics, Northwestern University, Chicago, Illinois.; Simpson Querrey Institute for Epigenetics, Northwestern University Feinberg School of Medicine, Chicago, Illinois., Amici DR; Department of Biochemistry and Molecular Genetics, Northwestern University, Chicago, Illinois.; Simpson Querrey Institute for Epigenetics, Northwestern University Feinberg School of Medicine, Chicago, Illinois.; Medical Scientist Training Program, Northwestern University Feinberg School of Medicine, Chicago, Illinois., Rendleman EJ; Department of Biochemistry and Molecular Genetics, Northwestern University, Chicago, Illinois.; Simpson Querrey Institute for Epigenetics, Northwestern University Feinberg School of Medicine, Chicago, Illinois., Rawat R; Department of Biochemistry and Molecular Genetics, Northwestern University, Chicago, Illinois.; Simpson Querrey Institute for Epigenetics, Northwestern University Feinberg School of Medicine, Chicago, Illinois.; Medical Scientist Training Program, Northwestern University Feinberg School of Medicine, Chicago, Illinois., Bresolin S; Oncohematology Laboratory, Department of Women's and Children's Health, University of Padova, Padova, Italy., Paganin M; Oncohematology Laboratory, Department of Women's and Children's Health, University of Padova, Padova, Italy., Zhang C; Department of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic, Rochester, Minnesota., Li H; Department of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic, Rochester, Minnesota., Kandela I; Center for Developmental Therapeutics, Northwestern University, Evanston, Illinois., Politanska Y; Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, Illinois., Abdala-Valencia H; Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, Illinois., Mendillo ML; Department of Biochemistry and Molecular Genetics, Northwestern University, Chicago, Illinois.; Simpson Querrey Institute for Epigenetics, Northwestern University Feinberg School of Medicine, Chicago, Illinois., Zhu P; H3 Biomedicine, Inc., Cambridge, Massachusetts., Palhais B; Cancer Research Institute Ghent (CRIG), Ghent, Belgium.; Department of Biomolecular Medicine, Ghent University, Ghent, Belgium., Van Vlierberghe P; Cancer Research Institute Ghent (CRIG), Ghent, Belgium.; Department of Biomolecular Medicine, Ghent University, Ghent, Belgium., Taghon T; Cancer Research Institute Ghent (CRIG), Ghent, Belgium.; Department of Diagnostic Sciences, Ghent University, Ghent, Belgium.; Faculty of Medicine and Health Sciences, Ghent University, Ghent, Belgium., Aifantis I; Department of Pathology and Laura & Isaac Perlmutter Cancer Center, New York University School of Medicine, New York, New York., Goo YA; Department of Biochemistry and Molecular Genetics, Northwestern University, Chicago, Illinois.; Proteomics Center of Excellence, Northwestern University, Evanston, Illinois., Guccione E; Department of Oncological Sciences and Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, New York.; Department of Pharmacological Sciences and Mount Sinai Center for Therapeutics Discovery, Icahn School of Medicine at Mount Sinai, New York, New York., Heguy A; Department of Pathology and Laura & Isaac Perlmutter Cancer Center, New York University School of Medicine, New York, New York.; Genome Technology Center, New York University School of Medicine, New York, New York., Tsirigos A; Department of Pathology and Laura & Isaac Perlmutter Cancer Center, New York University School of Medicine, New York, New York.; Applied Bioinformatics Laboratories, Office of Science and Research, New York University School of Medicine, New York, New York., Wee KB; Applied Bioinformatics Laboratories, Office of Science and Research, New York University School of Medicine, New York, New York.; Institute of Molecular and Cell Biology, Agency for Science, Technology and Research, Singapore., Mishra RK; Department of Biochemistry and Molecular Genetics, Northwestern University, Chicago, Illinois.; Center for Molecular Innovation and Drug Discovery, Northwestern University, Chicago, Illinois., Pflumio F; Team Niche and Cancer in hematopoiesis, CEA, Fontenay-aux-Roses, France.; Laboratory of Hematopoietic Stem Cells and Leukemia/Service Stem Cells and Radiation/iRCM/JACOB/DRF, CEA, Fontenay-aux-Roses, France., Accordi B; Oncohematology Laboratory, Department of Women's and Children's Health, University of Padova, Padova, Italy., Basso G; Oncohematology Laboratory, Department of Women's and Children's Health, University of Padova, Padova, Italy., Ntziachristos P; Department of Biochemistry and Molecular Genetics, Northwestern University, Chicago, Illinois. pntziachr@gmail.com.; Simpson Querrey Institute for Epigenetics, Northwestern University Feinberg School of Medicine, Chicago, Illinois.; Robert H. Lurie Comprehensive Cancer Center, Northwestern University, Chicago, Illinois.

Publikováno v: Cancer discovery [Cancer Discov] 2020 Sep; Vol. 10 (9), pp. 1388-1409. Date of Electronic Publication: 2020 May 22.

Mineralogical Implications of the Middle to Upper Jurassic Succession at Sargelu Village in Sulaymaniyah City, Northeastern Iraq.

Autor: Rasool, Rebwar H., Ali, Sarmad A., Al-Juboury, Ali I., Rowe, Harry, Zanoni, Giovanni

Publikováno v: Iraqi National Journal of Earth Sciences; Jul2024, Vol. 24 Issue 2, p212-230, 19p

Detrital zircon provenance record of the Zagros mountain building from the Neotethys obduction to the Arabia–Eurasia collision, NW Zagros fold–thrust belt, Kurdistan region of Iraq.

Autor: Koshnaw, Renas I.^1,2 (AUTHOR) renas.i.koshnaw@gmail.com, Schlunegger, Fritz² (AUTHOR), Stockli, Daniel F.³ (AUTHOR)

Publikováno v: Solid Earth. 11/29/2021, Vol. 12 Issue 11, p2479-2501. 23p.

Microbial Community Composition in Crude Oils and Asphalts from the Kurdistan Region of Iraq.

Autor: Shlimon, Adris G.¹ (AUTHOR) adris.shlimon@bios.au.dk, Mansurbeg, Howri^2,3 (AUTHOR), Othman, Rushdy S.² (AUTHOR), Gittel, Antje⁴ (AUTHOR), Aitken, Carolyn M.⁵ (AUTHOR), Head, Ian M.⁶ (AUTHOR), Finster, Kai W.⁴ (AUTHOR) kai.finster@bios.au.dk, Kjeldsen, Kasper U.⁴ (AUTHOR)

Publikováno v: Geomicrobiology Journal. Jul2020, Vol. 37 Issue 7, p635-652. 18p.