Apolipoprotein E genotype-dependent nutrigenetic effects to prebiotic inulin for modulating systemic metabolism and neuroprotection in mice via gut-brain axis.

Autor: Yanckello, Lucille M., Hoffman, Jared D., Chang, Ya-Hsuan, Lin, Penghui, Nehra, Geetika, Chlipala, George, McCulloch, Scott D., Hammond, Tyler C., Yackzan, Andrew T., Lane, Andrew N., Green, Stefan J., Hartz, Anika M. S., Lin, Ai-Ling

Publikováno v: Nutritional Neuroscience; Aug2022, Vol. 25 Issue 8, p1669-1679, 11p, 2 Charts, 6 Graphs

Functional recovery outcomes following acute stroke is associated with abundance of gut microbiota related to inflammation, butyrate and secondary bile acid.

Autor: Hammond TC; Sanders-Brown Center on Aging, University of Kentucky, Lexington, KY, United States.; Department of Neuroscience, University of Kentucky, Lexington, KY, United States., Powell E; Department of Physical Medicine and Rehabilitation, University of Kentucky, Lexington, KY, United States., Green SJ; Genomics and Microbiome Core Facility, Rush University, Chicago, IL, United States., Chlipala G; Research Informatics Core, University of Illinois Chicago, Chicago, IL, United States., Frank J; Department of Neuroscience, University of Kentucky, Lexington, KY, United States.; Center for Advanced Stroke Science, Department of Neurology, University of Kentucky, Lexington, KY, United States., Yackzan AT; Sanders-Brown Center on Aging, University of Kentucky, Lexington, KY, United States., Yanckello LM; Sanders-Brown Center on Aging, University of Kentucky, Lexington, KY, United States.; Department of Pharmacology and Nutritional Sciences, University of Kentucky, Lexington, KY, United States., Chang YH; Sanders-Brown Center on Aging, University of Kentucky, Lexington, KY, United States.; Department of Pharmacology and Nutritional Sciences, University of Kentucky, Lexington, KY, United States., Xing X; Sanders-Brown Center on Aging, University of Kentucky, Lexington, KY, United States.; Department of Computer Science, University of Kentucky, Lexington, KY, United States., Heil S; School of Medicine, University of Missouri, Columbia, MO, United States., Springer JE; Department of Neuroscience, University of Kentucky, Lexington, KY, United States.; Spinal Cord and Brain Injury Research Center, University of Kentucky, Lexington, KY, United States., Pennypacker K; Department of Neuroscience, University of Kentucky, Lexington, KY, United States.; Center for Advanced Stroke Science, Department of Neurology, University of Kentucky, Lexington, KY, United States., Stromberg A; Department of Statistics, University of Kentucky, Lexington, KY, United States., Sawaki L; Department of Physical Medicine and Rehabilitation, University of Kentucky, Lexington, KY, United States., Lin AL; Department of Radiology, University of Missouri, Columbia, MO, United States.; Institute for Data Science & Informatics, University of Missouri, Columbia, MO United States.; Department of Biological Sciences, University of Missouri, Columbia, MO, United States.

Publikováno v: Frontiers in rehabilitation sciences [Front Rehabil Sci] 2022 Oct 26; Vol. 3, pp. 1017180. Date of Electronic Publication: 2022 Oct 26 (Print Publication: 2022).