Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Yacine Touahri"'
Autor:
Yacine Touahri, Joseph Hanna, Nobuhiko Tachibana, Satoshi Okawa, Hedy Liu, Luke Ajay David, Thomas Olender, Lakshmy Vasan, Alissa Pak, Dhruv Nimesh Mehta, Vorapin Chinchalongporn, Anjali Balakrishnan, Robert Cantrup, Rajiv Dixit, Pierre Mattar, Fermisk Saleh, Yaroslav Ilnytskyy, Monzur Murshed, Paul E. Mains, Igor Kovalchuk, Julie L. Lefebvre, Hon S. Leong, Michel Cayouette, Chao Wang, Antonio del Sol, Marjorie Brand, Benjamin E. Reese, Carol Schuurmans
Publikováno v:
Cell Reports, Vol 43, Iss 4, Pp 114005- (2024)
Summary: The retina is exquisitely patterned, with neuronal somata positioned at regular intervals to completely sample the visual field. Here, we show that phosphatase and tensin homolog (Pten) controls starburst amacrine cell spacing by modulating
Externí odkaz:
https://doaj.org/article/1882f62fe92d4324a8d569020841d0d4
Autor:
Joseph Hanna, Luke Ajay David, Yacine Touahri, Taylor Fleming, Robert A. Screaton, Carol Schuurmans
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2022)
Vision commences in the retina with rod and cone photoreceptors that detect and convert light to electrical signals. The irreversible loss of photoreceptors due to neurodegenerative disease leads to visual impairment and blindness. Interventions now
Externí odkaz:
https://doaj.org/article/dbb91a1e1c6642ceb7f095a397d288c2
Autor:
Abdullah Al-Ani, Derek Toms, Saud Sunba, Kayla Giles, Yacine Touahri, Carol Schuurmans, Mark Ungrin
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 21, p 11317 (2021)
The retinal pigmented epithelium (RPE) plays a critical role in photoreceptor survival and function. RPE deficits are implicated in a wide range of diseases that result in vision loss, including age-related macular degeneration (AMD) and Stargardt di
Externí odkaz:
https://doaj.org/article/16d0ad101db2490ba6e8dec276be27c6
Autor:
Lata Adnani, Rajiv Dixit, Xingyu Chen, Anjali Balakrishnan, Harshil Modi, Yacine Touahri, Cairine Logan, Carol Schuurmans
Publikováno v:
Biology Open, Vol 7, Iss 11 (2018)
The Plag gene family has three members; Plagl1/Zac1, which is a tumor suppressor gene, and Plag1 and Plagl2, which are proto-oncogenes. All three genes are known to be expressed in embryonic neural progenitors, and Zac1 regulates proliferation, neuro
Externí odkaz:
https://doaj.org/article/0ed1111a88fc433493063216a053ea02
Autor:
Nobuhiko Tachibana, Yacine Touahri, Rajiv Dixit, Luke Ajay David, Lata Adnani, Robert Cantrup, Tooka Aavani, Rachel O. Wong, Cairine Logan, Kyle C. Kurek, Carol Schuurmans
Publikováno v:
Disease Models & Mechanisms, Vol 11, Iss 5 (2018)
PTEN hamartoma tumour syndrome (PHTS) is a heterogeneous group of rare, autosomal dominant disorders associated with PTEN germline mutations. PHTS patients routinely develop hamartomas, which are benign tissue overgrowths comprised of disorganized
Externí odkaz:
https://doaj.org/article/5e67aa0a2baf45eab61369be85e5394f
Autor:
Anjali Balakrishnan, Morgan G Stykel, Yacine Touahri, Jo Anne Stratton, Jeff Biernaskie, Carol Schuurmans
Publikováno v:
PLoS ONE, Vol 11, Iss 4, p e0153256 (2016)
Schwann cells (SCs) arise from neural crest cells (NCCs) that first give rise to SC precursors (SCPs), followed by immature SCs, pro-myelinating SCs, and finally, non-myelinating or myelinating SCs. After nerve injury, mature SCs 'de-differentiate',
Externí odkaz:
https://doaj.org/article/7bea34c313c543d69c070e26e5de47de
Autor:
Yacine Touahri, Luke Ajay David, Joseph Hanna, Satoshi Okawa, Hedy Liu, Yucheng Xiao, Alissa Pak, Yaroslav Ilnytskyy, Edwin van Oosten, Nobuhiko tachibana, Lata Adnani, Jiayi Zhao, Mary Hoffman, Rajiv Dixit, Dawn Zinyk, Cynthia J. Guidos, Volker Enzmann, Pengpeng Bi, Isabelle Aubert, Laurent Journot, Igor Kovalchuk, Yves Sauvé, Jeff Biernaskie, Chao Wang, Antonio del Sol, Carol Janine Schuurmans
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::71d25af604eeefe9fc3b34d7ffa7aa67
https://doi.org/10.2139/ssrn.4423987
https://doi.org/10.2139/ssrn.4423987
Autor:
Yacine Touahri, Joseph Hanna, Nobuhiko Tachibana, Luke Ajay David, Thomas Olender, Satoshi Okawa, Vorapin Chinchalongporn, Anjali Balakrishnan, Robert Cantrup, Rajiv Dixit, Pierre Mattar, Fermisk Saleh, Yaroslav Ilnytskyy, Monzur Murshed, Paul E. Mains, Igor Kovalchuk, Julie L Lefebvre, Michel Cayouette, Antonio del Sol, Marjorie Brand, Benjamin E Reese, Carol Schuurmans
SUMMARYThe retina is an exquisitely patterned tissue, with neuronal somata positioned at regular intervals to completely sample the visual field. Cholinergic amacrine cells are spectacular exemplars of precision, distributing in two radial layers and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9a05c29a0807e4f522161f5216a31a6b
https://doi.org/10.1101/2022.08.31.506085
https://doi.org/10.1101/2022.08.31.506085
Autor:
Kelly Markham-Coultes, Carol Schuurmans, Rajiv Dixit, Luke Ajay David, Kullervo Hynynen, Jiayi Zhao, Eunjee Park, Madelaine Lynch, Yacine Touahri, Kristina Miloska, Hibo Rijal, Reza Raeisossadati, Isabelle Aubert, Rikke Hahn Kofoed
Publikováno v:
Theranostics
Müller glia are specialized retinal cells with stem cell properties in fish and frogs but not in mammals. Current efforts to develop gene therapies to activate mammalian Müller glia for retinal repair will require safe and effective delivery strate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5483a5952a666d3a55a414e646ee6d63
https://doi.org/10.7150/thno.42611
https://doi.org/10.7150/thno.42611
Publikováno v:
Neuroscience in the 21st Century ISBN: 9781461464341
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f7f0033c2daf1e9fcba203140db32e6
https://doi.org/10.1007/978-1-4614-6434-1_182-1
https://doi.org/10.1007/978-1-4614-6434-1_182-1