Zobrazeno 1 - 10
of 77
pro vyhledávání: '"Yachun Han"'
Autor:
Jinfei Yang, Li Li, Chenrui Li, Wei Chen, Yan Liu, Shilu Luo, Chanyue Zhao, Yachun Han, Ming Yang, Hao Zhao, Na Jiang, Yiyun Xi, Chengyuan Tang, Juan Cai, Li Xiao, Huafeng Liu, Lin Sun
Publikováno v:
Cell Death and Disease, Vol 14, Iss 10, Pp 1-12 (2023)
Abstract Autophagy of endoplasmic reticulum (ER-phagy) selectively removes damaged ER through autophagy-lysosome pathway, acting as an adaptive mechanism to alleviate ER stress and restore ER homeostasis. However, the role and precise mechanism of ER
Externí odkaz:
https://doaj.org/article/9731d3a4b66a4489aa68f15a4684d600
Autor:
Yan Liu, Wei Chen, Chenrui Li, Li Li, Ming Yang, Na Jiang, Shilu Luo, Yiyun Xi, Chongbin Liu, Yachun Han, Hao Zhao, Xuejing Zhu, Shuguang Yuan, Li Xiao, Lin Sun
Publikováno v:
Redox Biology, Vol 66, Iss , Pp 102855- (2023)
Peroxisomes are metabolically active organelles that are known for exerting oxidative metabolism, but the precise mechanism remains unclear in diabetic nephropathy (DN). Here, we used proteomics to uncover a correlation between the antioxidant protei
Externí odkaz:
https://doaj.org/article/2083699a98664ad09d9ace8b31e17eb2
Autor:
Zebin Deng, Yilong Wang, Jiachen Liu, Hao Zhang, Lizhi Zhou, Hao Zhao, Yachun Han, Shu Yan, Zheng Dong, Yinhuai Wang, Yingbo Dai, Fei Deng
Publikováno v:
Redox Biology, Vol 65, Iss , Pp 102826- (2023)
Cisplatin is one of the major causes of acute kidney injury (AKI) in clinical practice, and ferroptosis is an essential form of cell death in cisplatin-induced AKI (CP-AKI). WW domain binding protein-2 (WBP2), a molecular chaperon, is involved in the
Externí odkaz:
https://doaj.org/article/8b81937e78684398b6d4c41783b682c6
Autor:
Xinyuan Cui, Yifu Li, Shuguang Yuan, Yao Huang, Xiaojun Chen, Yachun Han, Zhiwen Liu, Zheng Li, Yang Xiao, Youliang Wang, Lin Sun, Hong Liu, Xuejing Zhu
Publikováno v:
Biological Research, Vol 56, Iss 1, Pp 1-14 (2023)
Abstract Background Alpha‐kinase 1 (ALPK1) is a master regulator in inflammation and has been proved to promote renal fibrosis by promoting the production of IL-1β in diabetic nephropathy (DN) mice. Pyroptosis is involved in high glucose (HG)-indu
Externí odkaz:
https://doaj.org/article/460a112560ec46408fdf0a0091e28b97
PACS-2 deficiency in tubular cells aggravates lipid-related kidney injury in diabetic kidney disease
Autor:
Chanyue Zhao, Li Li, Chenrui Li, Chengyuan Tang, Juan Cai, Yu Liu, Jinfei Yang, Yiyun Xi, Ming Yang, Na Jiang, Yachun Han, Yan Liu, Shilu Luo, Li Xiao, Lin Sun
Publikováno v:
Molecular Medicine, Vol 28, Iss 1, Pp 1-14 (2022)
Abstract Background Lipid accumulation in tubular cells plays a key role in diabetic kidney disease (DKD). Targeting lipid metabolism disorders has clinical value in delaying the progression of DKD, but the precise mechanism by which molecules mediat
Externí odkaz:
https://doaj.org/article/af9f574304b546e88f4a17bbe788984d
Autor:
Ming Yang, Chongbin Liu, Na Jiang, Yan Liu, Shilu Luo, Chenrui Li, Hao Zhao, Yachun Han, Wei Chen, Li Li, Li Xiao, Lin Sun
Publikováno v:
Frontiers in Endocrinology, Vol 14 (2023)
Metabolic syndrome is a complex metabolic disorder that often clinically manifests as obesity, insulin resistance/diabetes, hyperlipidemia, and hypertension. With the development of social and economic systems, the incidence of metabolic syndrome is
Externí odkaz:
https://doaj.org/article/1c6b3445890440d994749e16a70ade07
Autor:
Ming Yang, Chongbin Liu, Na Jiang, Yan Liu, Shilu Luo, Chenrui Li, Hao Zhao, Yachun Han, Wei Chen, Li Li, Li Xiao, Lin Sun
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2023)
Mitochondria, which are the energy factories of the cell, participate in many life activities, and the kidney is a high metabolic organ that contains abundant mitochondria. Renal aging is a degenerative process associated with the accumulation of har
Externí odkaz:
https://doaj.org/article/a3b6dd9ffef64855bf824ab0716da878
Autor:
Ming Yang, Chongbin Liu, Na Jiang, Yan Liu, Shilu Luo, Chenrui Li, Hao Zhao, Yachun Han, Wei Chen, Li Li, Li Xiao, Lin Sun
Publikováno v:
Frontiers in Endocrinology, Vol 14 (2023)
The endoplasmic reticulum (ER) is the most vigorous organelle in intracellular metabolism and is involved in physiological processes such as protein and lipid synthesis and calcium ion transport. Recently, the abnormal function of the ER has also bee
Externí odkaz:
https://doaj.org/article/7315026e59084fe382708bb1c5c42878
Autor:
Ming Yang, Chongbin Liu, Na Jiang, Yan Liu, Shilu Luo, Chenrui Li, Hao Zhao, Yachun Han, Wei Chen, Li Li, Li Xiao, Lin Sun
Publikováno v:
Frontiers in Endocrinology, Vol 14 (2023)
Metabolic syndrome is a complex metabolic disorder, its main clinical manifestations are obesity, hyperglycemia, hypertension and hyperlipidemia. Although metabolic syndrome has been the focus of research in recent decades, it has been proposed that
Externí odkaz:
https://doaj.org/article/ba79638c60c041b3a5d77758c40e4b27
Autor:
Yachun Han, Shan Xiong, Hao Zhao, Shikun Yang, Ming Yang, Xuejing Zhu, Na Jiang, Xiaofen Xiong, Peng Gao, Ling Wei, Ying Xiao, Lin Sun
Publikováno v:
Cell Death and Disease, Vol 12, Iss 11, Pp 1-13 (2021)
Abstract Autophagy-mediated lipotoxicity plays a critical role in the progression of diabetic nephropathy (DN), but the precise mechanism is not fully understood. Whether lipophagy, a selective type of autophagy participates in renal ectopic lipid de
Externí odkaz:
https://doaj.org/article/739a1631b7ba42bdb65dbc2a697c6531