Zobrazeno 1 - 10
of 41
pro vyhledávání: '"Yachuan Zhou"'
Autor:
Si Wu, Xin Xu, Shiqi Gao, Sibei Huo, Mian Wan, Xin Zhou, Xuedong Zhou, Liwei Zheng, Yachuan Zhou
Publikováno v:
Journal of Translational Medicine, Vol 22, Iss 1, Pp 1-13 (2024)
Abstract Background Epigenetic factors influence the odontogenic differentiation of dental pulp stem cells and play indispensable roles during tooth development. Some microRNAs can epigenetically regulate other epigenetic factors like DNA methyltrans
Externí odkaz:
https://doaj.org/article/12f349c578ef45379a517925a9a3572f
Autor:
Yue Pan, Ying Liu, Dixin Cui, Sihan Yu, Yachuan Zhou, Xin Zhou, Wei Du, Liwei Zheng, Mian Wan
Publikováno v:
BMC Oral Health, Vol 23, Iss 1, Pp 1-13 (2023)
Abstract Background The dentinogenesis differentiation of dental pulp stem cells (DPSCs) is controlled by the spatio-temporal expression of differentiation related genes. RNA N6-methyladenosine (m6A) methylation, one of the most abundant internal epi
Externí odkaz:
https://doaj.org/article/520e0044be274923a7bbe4c9fdd6cdea
Publikováno v:
Journal of Translational Medicine, Vol 20, Iss 1, Pp 1-15 (2022)
Abstract Background N6-methyladenosine (m6A) is the most prevalent epigenetic modification in eukaryotic messenger RNAs and plays a critical role in cell fate transition. However, it remains to be elucidated how m6A marks functionally impact the tran
Externí odkaz:
https://doaj.org/article/333bfa53e6664b219ef27950b1a16428
Publikováno v:
Stem Cells International, Vol 2022 (2022)
Epigenetic regulation can dynamically adjust the gene expression program of cell fate decision according to the cellular microenvironment. Emerging studies have shown that metabolic activities provide fundamental components for epigenetic modificatio
Externí odkaz:
https://doaj.org/article/b46de4b4bbec4342b4e0ee8dbe752d4d
Publikováno v:
Stem Cells International, Vol 2021 (2021)
As the earliest studied epigenetic modification, acetylation has been explored a lot through the years. While bone tissue acts as an indispensable part of body, researches aimed at the relationship between the bone and acetylation became necessary. S
Externí odkaz:
https://doaj.org/article/381a8eb537c14687b26658faeac0a944
Autor:
Dan Zhou, Lu Gan, Yiran Peng, Yachuan Zhou, Xin Zhou, Mian Wan, Yi Fan, Xin Xu, Xuedong Zhou, Liwei Zheng, Wei Du
Publikováno v:
Stem Cells International, Vol 2020 (2020)
Epigenetic regulation, mainly involving DNA methylation, histone modification, and noncoding RNAs, affects gene expression without modifying the primary DNA sequence and modulates cell fate. Mesenchymal stem cells derived from dental pulp, also calle
Externí odkaz:
https://doaj.org/article/d0df6f8922dc4e25918bfc98b3d95d25
Autor:
Si Wu, Yachuan Zhou, Yi Yu, Xin Zhou, Wei Du, Mian Wan, Yi Fan, Xuedong Zhou, Xin Xu, Liwei Zheng
Publikováno v:
Stem Cells International, Vol 2019 (2019)
The pulpotomy with pulp capping is aimed at retaining vital pulp with reparative dentin formation. Vascular endothelial growth factor (VEGF) plays a crucial role in dentin regeneration; however, its constant administrations in the human body is still
Externí odkaz:
https://doaj.org/article/a8d3297187534450a71617ab50170698
Autor:
Si Wu, Jun Zhang, Feifei Li, Wei Du, Xin Zhou, Mian Wan, Yi Fan, Xin Xu, Xuedong Zhou, Liwei Zheng, Yachuan Zhou
Publikováno v:
Stem Cells International, Vol 2019 (2019)
Beyond energy production, nutrient metabolism plays a crucial role in stem cell lineage determination. Changes in metabolism based on nutrient availability and dietary habits impact stem cell identity. Evidence suggests a strong link between metaboli
Externí odkaz:
https://doaj.org/article/3d67e3b19b884df68a7c9ed92ac0a5d3
Autor:
Tao Zhou, Jinhai Pan, Peiyao Wu, Ruijie Huang, Wei Du, Yachuan Zhou, Mian Wan, Yi Fan, Xin Xu, Xuedong Zhou, Liwei Zheng, Xin Zhou
Publikováno v:
Stem Cells International, Vol 2019 (2019)
Dental follicle cells (DFCs) are a group of mesenchymal progenitor cells surrounding the tooth germ, responsible for cementum, periodontal ligament, and alveolar bone formation in tooth development. Cascades of signaling pathways and transcriptional
Externí odkaz:
https://doaj.org/article/35cb3aa24b49434bae3a1a40200a93ce
Publikováno v:
Stem Cells International, Vol 2017 (2017)
Temporomandibular joint osteoarthritis (TMJ OA) is a degenerative disease, characterized by progressive cartilage degradation, subchondral bone remodeling, synovitis, and chronic pain. Due to the limited self-healing capacity in condylar cartilage, t
Externí odkaz:
https://doaj.org/article/1a4d7613704049e98df530d8ef34cbc4