Zobrazeno 1 - 10
of 113
pro vyhledávání: '"Yaakov Nahmias"'
Autor:
Avner Ehrlich, Konstantinos Ioannidis, Makram Nasar, Ismaeel Abu Alkian, Yuval Daskal, Nofar Atari, Limor Kliker, Nir Rainy, Matan Hofree, Sigal Shafran Tikva, Inbal Houri, Arrigo Cicero, Chiara Pavanello, Cesare R Sirtori, Jordana B Cohen, Julio A Chirinos, Lisa Deutsch, Merav Cohen, Amichai Gottlieb, Adina Bar-Chaim, Oren Shibolet, Michal Mandelboim, Shlomo L Maayan, Yaakov Nahmias
Publikováno v:
eLife, Vol 12 (2023)
Background: Viral infection is associated with a significant rewire of the host metabolic pathways, presenting attractive metabolic targets for intervention. Methods: We chart the metabolic response of lung epithelial cells to SARS-CoV-2 infection in
Externí odkaz:
https://doaj.org/article/e2c42bb8edf74ef282600cb66a73a2be
Autor:
Rossana Rauti, Meishar Shahoha, Yael Leichtmann-Bardoogo, Rami Nasser, Eyal Paz, Rina Tamir, Victoria Miller, Tal Babich, Kfir Shaked, Avner Ehrlich, Konstantinos Ioannidis, Yaakov Nahmias, Roded Sharan, Uri Ashery, Ben Meir Maoz
Publikováno v:
eLife, Vol 10 (2021)
Severe acute respiratory syndrome (SARS)-CoV-2 infection leads to severe disease associated with cytokine storm, vascular dysfunction, coagulation, and progressive lung damage. It affects several vital organs, seemingly through a pathological effect
Externí odkaz:
https://doaj.org/article/2e26a1ded88e455da9a8f989c971aa4f
Autor:
Ola Karmi, Yang-Sung Sohn, Henri-Baptiste Marjault, Tal Israeli, Gil Leibowitz, Konstantinos Ioannidis, Yaakov Nahmias, Ron Mittler, Ioav Z. Cabantchik, Rachel Nechushtai
Publikováno v:
Antioxidants, Vol 10, Iss 8, p 1160 (2021)
Decreased insulin secretion, associated with pancreatic β-cell failure, plays a critical role in many human diseases including diabetes, obesity, and cancer. While numerous studies linked β-cell failure with enhanced levels of reactive oxygen speci
Externí odkaz:
https://doaj.org/article/445d18587fbe4b629ebd01f35f244779
Autor:
Laura Ordovás, Ruben Boon, Mariaelena Pistoni, Yemiao Chen, Esther Wolfs, Wenting Guo, Rangarajan Sambathkumar, Sylwia Bobis-Wozowicz, Nicky Helsen, Jolien Vanhove, Pieter Berckmans, Qing Cai, Kim Vanuytsel, Kristel Eggermont, Veerle Vanslembrouck, Béla Z. Schmidt, Susanna Raitano, Ludo Van Den Bosch, Yaakov Nahmias, Toni Cathomen, Tom Struys, Catherine M. Verfaillie
Publikováno v:
Stem Cell Reports, Vol 5, Iss 5, Pp 918-931 (2015)
Tools for rapid and efficient transgenesis in “safe harbor” loci in an isogenic context remain important to exploit the possibilities of human pluripotent stem cells (hPSCs). We created hPSC master cell lines suitable for FLPe recombinase-mediate
Externí odkaz:
https://doaj.org/article/104293e2640a470085393893e506221e
Autor:
Meytal Radzinski, Rosi Fassler, Ohad Yogev, William Breuer, Nadav Shai, Jenia Gutin, Sidra Ilyas, Yifat Geffen, Sabina Tsytkin-Kirschenzweig, Yaakov Nahmias, Tommer Ravid, Nir Friedman, Maya Schuldiner, Dana Reichmann
Publikováno v:
eLife, Vol 7 (2018)
Cellular redox status affects diverse cellular functions, including proliferation, protein homeostasis, and aging. Thus, individual differences in redox status can give rise to distinct sub-populations even among cells with identical genetic backgrou
Externí odkaz:
https://doaj.org/article/d0840b033b04419592b96828f318e0ba
Autor:
Laura Ordovás, Ruben Boon, Mariaelena Pistoni, Yemiao Chen, Esther Wolfs, Wenting Guo, Rangarajan Sambathkumar, Sylwia Bobis-Wozowicz, Nicky Helsen, Jolien Vanhove, Pieter Berckmans, Qing Cai, Kim Vanuytsel, Kristel Eggermont, Veerle Vanslembrouck, Béla Z. Schmidt, Susanna Raitano, Ludo Van Den Bosch, Yaakov Nahmias, Toni Cathomen, Tom Struys, Catherine M. Verfaillie
Publikováno v:
Stem Cell Reports, Vol 10, Iss 2, Pp 673- (2018)
Externí odkaz:
https://doaj.org/article/93ada59455364727a50a5205739b2eef
Autor:
Rachel Spokoini, Ofer Moldavski, Yaakov Nahmias, Jeremy L. England, Maya Schuldiner, Daniel Kaganovich
Publikováno v:
Cell Reports, Vol 2, Iss 4, Pp 738-747 (2012)
The division of the S. cerevisiae budding yeast, which produces one mother cell and one daughter cell, is asymmetric with respect to aging. Remarkably, the asymmetry of yeast aging coincides with asymmetric inheritance of damaged and aggregated prote
Externí odkaz:
https://doaj.org/article/cc3bb23f3d3c4a43b8b553e093aaf12d
Autor:
Benjamin D Harrison, Jordan Hashemi, Maayan Bibi, Rebecca Pulver, Danny Bavli, Yaakov Nahmias, Melanie Wellington, Guillermo Sapiro, Judith Berman
Publikováno v:
PLoS Biology, Vol 12, Iss 3, p e1001815 (2014)
Candida albicans, the most prevalent human fungal pathogen, is generally diploid. However, 50% of isolates that are resistant to fluconazole (FLC), the most widely used antifungal, are aneuploid and some aneuploidies can confer FLC resistance. To ask
Externí odkaz:
https://doaj.org/article/2a1ac39e77b147f2b6b2b890f5c3243d
Live imaging of GLUT2 glucose-dependent trafficking and its inhibition in polarized epithelial cysts
Publikováno v:
Open Biology, Vol 4, Iss 7 (2014)
GLUT2 is a facilitative glucose transporter, expressed in polarized epithelial cells of the liver, intestine, kidney and pancreas, where it plays a critical role in glucose homeostasis. Together with SGLT1/2, it mediates glucose absorption in metabol
Externí odkaz:
https://doaj.org/article/d42379337114457f9765ac555991ff79
Autor:
Ji Bao, James E. Fisher, Joseph B. Lillegard, William Wang, Bruce Amiot, Yue Yu, Allan B. Dietz, Yaakov Nahmias, Scott L. Nyberg M.D., Ph.D.
Publikováno v:
Cell Transplantation, Vol 22 (2013)
Long-term culture of hepatocyte spheroids with high ammonia clearance is valuable for therapeutic applications, especially the bioartificial liver. However, the optimal conditions are not well studied. We hypothesized that liver urea cycle enzymes ca
Externí odkaz:
https://doaj.org/article/a9425221a3f94447abe3ca8f3d8cfe1b