Výsledky vyhledávání - "Ya. G. Gorchakova"

Akademický článek

Exacerbation of asthma and neutrophil-dominated airway inflammation in patients with cold-induced airway hyperresponsiveness

Autor: A. B. Pirogov, A. G. Prikhodko, E. Yu. Afanaseva, E. G. Sheludko, Ya. G. Gorchakova, X. Zhou, Q. Li, Yu. M. Perelman

Publikováno v: Бюллетень сибирской медицины, Vol 20, Iss 2, Pp 71-78 (2021)

Background. Neutrophils can play a significant role in the formation of bronchial inflammation in asthma exacerbation in patients with cold-induced airway hyperresponsiveness (CIAHR).Aim. To evaluate the role of neutrophils in the dynamics of the inf

Externí odkaz: https://doaj.org/article/c911ee25fab0466fbaceb6f0e8c5977f

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The influence of TRPM8 polymorphism on the progression of bronchial obstruction in patients with chronic obstructive pulmonary disease

Autor: I. Yu. Sugaylo, D. A. Gassan, O. O. Kotova, D. E. Naumov, Ya. G. Gorchakova, E. G. Sheludko, E. Yu. Afanas'eva

Publikováno v: Bulletin Physiology and Pathology of Respiration. 1:15-23

Introduction. Chronic obstructive pulmonary disease (COPD) is a severe respiratory pathology, the main risk factor for which is tobacco smoking. The progression of bronchial obstruction is subject to individual variability which indicates an importan

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::fee99e2e01c4972e1e896789b2b785e8
https://doi.org/10.36604/1998-5029-2022-86-15-23

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Peculiarities of TRP channels expression and cytokine profile of sputum in patients with chronic obstructive pulmonary disease and progressive bronchial obstruction

Autor: D. E. Naumov, I. Yu. Sugaylo, D. A. Gassan, O. O. Kotova, Ya. G. Gorchakova, E. G. Sheludko

Publikováno v: Bulletin Physiology and Pathology of Respiration. 1:24-32

Introduction. Chronic obstructive pulmonary disease (COPD) is a pathology accompanied by a progressive and irreversible deterioration in airway patency. It is known that macrophages of the respiratory tract are actively involved in the reorganizati

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::213607041747561a29b029629ee43161
https://doi.org/10.36604/1998-5029-2022-86-24-32

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Modulating effect of TRPA1 and TRPM8 channels on cytokine production by pro- and anti-inflammatory macrophages

Autor: O. O. Kotova, D. A. Gassan, D. E. Naumov, I. Yu. Sugaylo, Ya. G. Gorchakova

Publikováno v: Bulletin Physiology and Pathology of Respiration. 1:33-39

Introduction. Transient receptor potential (TRP) channels expressed on many cells, including macrophages, are an attractive target for pharmacological modulation for the treatment of various diseases. At the same time, currently available data on t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d3e5c5ff3801c1fa956f183675950644
https://doi.org/10.36604/1998-5029-2022-86-33-39

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Comparative characteristics of TRP channels expression levels on the macrophages of patients with chronic obstructive pulmonary disease

Autor: D. E. Naumov, I. Yu. Sugaylo, O. O. Kotova, D. A. Gassan, Ya. G. Gorchakova, T. A. Maltseva

Publikováno v: Bulletin Physiology and Pathology of Respiration. :37-46

Introduction. Macrophages are one of the key cells in the pathogenesis of chronic obstructive pulmonary disease (COPD), mediating the primary immune response and coordinating the further reaction of the immune system upon contact with cigarette smoke

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::0e16da99871a7506f23c5f0e22e980b5
https://doi.org/10.36604/1998-5029-2022-85-37-46

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TRPA1-mediated effects on the functional activity of macrophages under the exposure with cigarette smoke and cinnamaldehyde

Autor: I. Yu. Sugaylo, D. E. Naumov, O. O. Kotova, D. A. Gassan, Ya. G. Gorchakova

Publikováno v: Bulletin Physiology and Pathology of Respiration. :28-36

Introduction. Being the leading cause of COPD, smoking represents a major health problem. Upon entering the respiratory tract, cigarette smoke comes into contact with various cells, including macrophages expressing on their surface TRPA1 receptors, w

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::da1df05d2c6661dec8f04298e4cefce4
https://doi.org/10.36604/1998-5029-2021-82-28-36

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