Zobrazeno 1 - 10
of 57
pro vyhledávání: '"Ya-song Du"'
Identification of autism-related MECP2 mutations by whole-exome sequencing and functional validation
Autor:
Zhu Wen, Tian-Lin Cheng, Gai-zhi Li, Shi-Bang Sun, Shun-Ying Yu, Yi Zhang, Ya-Song Du, Zilong Qiu
Publikováno v:
Molecular Autism, Vol 8, Iss 1, Pp 1-10 (2017)
Abstract Background Methyl-CpG-binding protein-2 (MeCP2) is a critical regulator for neural development. Either loss- or gain-of-function leads to severe neurodevelopmental disorders, such as Rett syndrome (RTT) and autism spectrum disorder (ASD). We
Externí odkaz:
https://doaj.org/article/bcb818112c014d34957c09cb7517883d
Autor:
Da-li Tong, Rui-guo Chen, Yu-lan Lu, Wei-ke Li, Yue-fang Zhang, Jun-kai Lin, Ling-jie He, Ting Dang, Shi-fang Shan, Xiao-Hong Xu, Yi Zhang, Chen Zhang, Ya-Song Du, Wen-Hao Zhou, Xiaoqun Wang, Zilong Qiu
Publikováno v:
Neurobiology of Disease, Vol 130, Iss , Pp 104486- (2019)
Accumulated genetic evidences indicate that the contactin associated protein-like (CNTNAP) family is implicated in autism spectrum disorders (ASD). In this study, we identified genetic mutations in the CNTNAP3 gene from Chinese Han ASD cohorts and Si
Externí odkaz:
https://doaj.org/article/4ad3b1b4e13d42ee8a8928cc06d08bbf
Autor:
Yao Wang, Yan Yin, Ya-wen Sun, Yan Zhou, Xue Chen, Wei-na Ding, Wei Wang, Wei Li, Jian-rong Xu, Ya-song Du
Publikováno v:
PLoS ONE, Vol 10, Iss 3, p e0118733 (2015)
Recent neuroimaging studies have shown that people with Internet gaming disorder (IGD) have structural and functional abnormalities in specific brain areas and connections. However, little is known about the alterations of the interhemispheric restin
Externí odkaz:
https://doaj.org/article/7cea61295228423f8d7a1f3b9d4761a9
Publikováno v:
Social Behavior and Personality: an international journal. 47:1-20
In China, mothers of children with autism spectrum disorder struggle with parenting, often becoming depressed. This can harm the well-being and sociocognitive development of their children. We determined whether a psychoeducational group intervention
Publikováno v:
PLoS ONE, Vol 8, Iss 3, p e59902 (2013)
PurposeExcessive use of the Internet has been linked to a variety of negative psychosocial consequences. This study used resting-state functional magnetic resonance imaging (fMRI) to investigate whether functional connectivity is altered in adolescen
Externí odkaz:
https://doaj.org/article/be65433556eb4f2fbda4e56fbf6b08d0
Publikováno v:
PLoS ONE, Vol 8, Iss 5, p e63089 (2013)
BACKGROUND: Internet addiction disorder (IAD) is now recognized internationally and is known to be linked with academic and social impairment. To date, we know little about its associated main biological factors. This study aimed to collect a careful
Externí odkaz:
https://doaj.org/article/86406583ba89441396cf396e6a8a1643
Autor:
Richard H. Finnell, Yu Fang Zheng, Si Yu Yang, Zhang Min Yang, Ya Song Du, Dong Liu, Zilong Qiu, Hongyan Wang, Y Wang, Lin Na Zhang, Yan Qin He, Xiao Hong Gong
Publikováno v:
Cell Death and Differentiation
Duplication of MECP2 (Methyl-CpG-binding protein 2) causes severe mental illness called MECP2 duplication syndrome (MDS), yet the underlying mechanism remains elusive. Here we show, in Tg(MECP2) transgenic mouse brain or cultured neural progenitor ce
Autor:
Wen-qing Jiang, Xilong Cui, Han-yu Zhou, Li-juan Shi, Anna R. Docherty, Simon S.Y. Lui, Ya-song Du, Yun Qian, Raymond C.K. Chan, Eric F.C. Cheung, Keri Ka-Yee Wong, Zheng-hui Yi, Xue-rong Luo
Publikováno v:
Schizophrenia Research. 199:135-141
Background We validated the Social Mistrust Scale (SMS) and utilized it to examine the structure, prevalence, and heritability of social mistrust in a large sample of Chinese children and adolescents. Methods In Study 1, a large sample of healthy twi
Publikováno v:
The European Journal of Psychiatry. 31:59-65
Background and objective The cognitive abilities of individuals with autism spectrum disorder (ASD) vary widely, but studies have not yet examined Chinese school-aged boys with ASD in a systematic way. This study aims to explore the IQ profile of Chi
Publikováno v:
Asia-Pacific Psychiatry. 8:127-135
Introduction To identify the characteristics of behavior problems among children with attention deficit hyperactivity disorder (ADHD) and their relation with parenting stress. Methods The Conners Parent Symptom Questionnaire (PSQ) and Parenting Stres