Aryl hydrocarbon receptor activation mediates kidney disease and renal cell carcinoma

Autor: Hui Zhao, Lin Chen, Tian Yang, Ya-Long Feng, Nosratola D. Vaziri, Bao-Li Liu, Qing-Quan Liu, Yan Guo, Ying-Yong Zhao

Publikováno v: Journal of Translational Medicine, Vol 17, Iss 1, Pp 1-14 (2019)

Abstract The aryl hydrocarbon receptor (AhR) is a well-known ligand-activated cytoplasmic transcription factor that contributes to cellular responses against environmental toxins and carcinogens. AhR is activated by a range of structurally diverse co

Externí odkaz: https://doaj.org/article/520c99a0dcd64c8089b23be2ce982aca

Cloud-Point Extraction Combined with Liquid Chromatography for the Determination of Ergosterol, a Natural Product with Diuretic Activity, in Rat Plasma, Urine, and Faeces

Autor: Dan-Qian Chen, Jun-Min An, Ya-Long Feng, Ting Tian, Xiang-Yang Qin, Ying-Yong Zhao

Publikováno v: Journal of Analytical Methods in Chemistry, Vol 2013 (2013)

Ergosterol from many medicinal fungi has been demonstrated to possess a variety of pharmacological activities in vivo and in vitro. A new method based on cloud-point extraction has been developed, optimized and validated for the determination of ergo

Externí odkaz: https://doaj.org/article/2fae9502bcd74a22a0a455d19ea7d543

Molecular mechanism of Panax ginseng C. A. Meyer against renal fibrosis based on network pharmacology and molecular docking analysis

Autor: Ya-long Feng, Hui-min Cai, Hui Zhao, Xin-yu Zhang, Lu-qing Wang, Lu-lu Cai, Wenlei Wang, You-ling Shan, Wen-bo Wang

Renal fibrosis (RF) cause a high morbidity and mortality, while the therapeutic drugs are needed. Panax ginseng C.A. Meyer (PG) was used to treat RF for a long history in China. However, the bioactive components and their corresponding mechanisms are

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::19e966f6e7be329ba681829d04393aae
https://doi.org/10.21203/rs.3.rs-2661141/v1

The

Autor: Hui, Zhao, Ya-Long, Feng, Ming, Wang, Jing-Jing, Wang, Tian, Liu, Jun, Yu

Publikováno v: Frontiers in pharmacology. 13

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::8e5d3cfea0922a506bd77440af20529c
https://pubmed.ncbi.nlm.nih.gov/35847034

Unilateral ureteral obstruction causes gut microbial dysbiosis and metabolome disorders contributing to tubulointerstitial fibrosis

Autor: Ying-Yong Zhao, Shougang Zhuang, Jun Zhang, Lin Chen, Ya-Long Feng, Yan Guo, Nosratola D. Vaziri, Dan-Qian Chen, Jing-Ru Liu, Hua Chen

Publikováno v: Chen, Lin; Chen, Dan-Qian; Liu, Jing-Ru; Zhang, Jun; Vaziri, Nosratola D; Zhuang, Shougang; et al.(2019). Unilateral ureteral obstruction causes gut microbial dysbiosis and metabolome disorders contributing to tubulointerstitial fibrosis.. Experimental & molecular medicine, 51(3), 38. doi: 10.1038/s12276-019-0234-2. UC Irvine: Retrieved from: http://www.escholarship.org/uc/item/3f51v0w7
Experimental & molecular medicine, vol 51, iss 3
Experimental and Molecular Medicine, Vol 51, Iss 3, Pp 1-18 (2019)
Experimental & Molecular Medicine

Chronic kidney disease (CKD) increases the risk and prevalence of cardiovascular disease (CVD) morbidity and mortality. Recent studies have revealed marked changes in the composition of the microbiome and the metabolome and their potential influence

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::359f3ce5c2e055d77f7229c21271085b
https://doi.org/10.1038/s12276-019-0234-2