Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Ya-lan Tan"'
Publikováno v:
Molecules, Vol 29, Iss 6, p 1244 (2024)
RNAs play crucial roles in various essential biological functions, including catalysis and gene regulation. Despite the widespread use of coarse-grained (CG) models/simulations to study RNA 3D structures and dynamics, their direct application is chal
Externí odkaz:
https://doaj.org/article/e7fa5ce1357c4f27bf9409561dcaad34
Publikováno v:
PLoS Computational Biology, Vol 18, Iss 10, p e1010501 (2022)
The three-dimensional (3D) structure and stability of DNA are essential to understand/control their biological functions and aid the development of novel materials. In this work, we present a coarse-grained (CG) model for DNA based on the RNA CG mode
Externí odkaz:
https://doaj.org/article/099acec9f29f4c6995e4ef02fa9c8fb5
Publikováno v:
Molecules, Vol 28, Iss 14, p 5532 (2023)
Ribonucleic acid (RNA) molecules play vital roles in numerous important biological functions such as catalysis and gene regulation. The functions of RNAs are strongly coupled to their structures or proper structure changes, and RNA structure predicti
Externí odkaz:
https://doaj.org/article/71246e2cf5a341a5b065fa873d9fb1a9
Publikováno v:
Molecules, Vol 28, Iss 12, p 4833 (2023)
DNA carries the genetic information required for the synthesis of RNA and proteins and plays an important role in many processes of biological development. Understanding the three-dimensional (3D) structures and dynamics of DNA is crucial for underst
Externí odkaz:
https://doaj.org/article/15aa2926ca444f2aa79e920fe1f3f7e7
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-8 (2021)
Abstract The general condition, clinical and pathological characteristics, and treatment regimens of patients prenatally and postnatally diagnosed with congenital choledochal malformation (CM) were analyzed in order to investigate the clinical signif
Externí odkaz:
https://doaj.org/article/931c8d3627424c389e1c1ae7cc5d0deb
Publikováno v:
Frontiers in Bioinformatics, Vol 1 (2022)
The 3D architectures of RNAs are essential for understanding their cellular functions. While an accurate scoring function based on the statistics of known RNA structures is a key component for successful RNA structure prediction or evaluation, there
Externí odkaz:
https://doaj.org/article/9dcc9b1128e64ab3b215fdab466ed6e1
Publikováno v:
Frontiers in Molecular Biosciences, Vol 8 (2021)
Macromolecules, such as RNAs, reside in crowded cell environments, which could strongly affect the folded structures and stability of RNAs. The emergence of RNA-driven phase separation in biology further stresses the potential functional roles of mol
Externí odkaz:
https://doaj.org/article/1700e70ec58149d786bae9c4636a5d95
Publikováno v:
Brazilian Journal of Medical and Biological Research, Vol 53, Iss 8 (2020)
This is a retrospective, single-center observational study to explore the predictors of chest drainage for neonatal pneumothorax. A total of 183 neonates (age ≤28 days) who presented to the Children's Hospital of Soochow University between January
Externí odkaz:
https://doaj.org/article/24d67041f1aa451eb6dd4110d816f08d
Publikováno v:
PLoS Computational Biology, Vol 14, Iss 6, p e1006222 (2018)
RNA pseudoknots are a kind of minimal RNA tertiary structural motifs, and their three-dimensional (3D) structures and stability play essential roles in a variety of biological functions. Therefore, to predict 3D structures and stability of RNA pseudo
Externí odkaz:
https://doaj.org/article/c0995cbbc7864204bafbdf0a8278d38a
Publikováno v:
Biophysical Journal. 122:1503-1516
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::909da7c9b92bbed98c792fc09d7b6bdb
https://doi.org/10.1016/j.bpj.2023.03.017
https://doi.org/10.1016/j.bpj.2023.03.017