Zobrazeno 1 - 10
of 55
pro vyhledávání: '"Ya-jun Deng"'
Autor:
Ya-Jun Deng, Xin-Gang Wang, Zhi Li, Bo Wang, Jie Li, Jun Ma, Xiong Xue, Xin Tian, Quan-Cheng Liu, Jia-Yuan Liu, Ying Zhang, Bin Yuan
Publikováno v:
Frontiers in Molecular Biosciences, Vol 10 (2023)
Objectives: This study aims to identify the key senescence genes and potential regulatory mechanisms that contribute to the etiology of intervertebral disc degeneration (IDD).Method: We analyzed GSE34095 and GSE70362 datasets, identifying key senesce
Externí odkaz:
https://doaj.org/article/bf82943d19344035aeb10eea13e88361
Autor:
Ya-Jun Deng, Zhi Li, Bo Wang, Jie Li, Jun Ma, Xiong Xue, Xin Tian, Quan-Cheng Liu, Ying Zhang, Bin Yuan
Publikováno v:
Frontiers in Genetics, Vol 14 (2023)
Objectives: Bone immune disorders are major contributors to osteoporosis development. This study aims to identify potential diagnostic markers and molecular targets for osteoporosis treatment from an immunological perspective.Method: We downloaded da
Externí odkaz:
https://doaj.org/article/007af81ef8494791bd9694277cbde544
Screening of osteoarthritis diagnostic markers based on immune-related genes and immune infiltration
Autor:
Wen-Hua Yuan, Qi-Qi Xie, Ke-Ping Wang, Wei Shen, Xiao-Fei Feng, Zheng Liu, Jin-Tao Shi, Xiao-Bo Zhang, Kai Zhang, Ya-Jun Deng, Hai-Yu Zhou
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
Abstract Osteoarthritis (OA) is a chronic degenerative disease of the bone and joints. Immune-related genes and immune cell infiltration are important in OA development. We analyzed immune-related genes and immune infiltrates to identify OA diagnosti
Externí odkaz:
https://doaj.org/article/086cea24440a4b17ac1002a105dc661e
Publikováno v:
Frontiers in Molecular Biosciences, Vol 8 (2021)
BackgroundOsteosarcoma is a frequent bone malignancy in children and young adults. Despite the availability of some prognostic biomarkers, most of them fail to accurately predict prognosis in osteosarcoma patients. In this study, we used bioinformati
Externí odkaz:
https://doaj.org/article/f9e39042349a43b2bb7f3c54acc5e4c8
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
The aim of this study was to construct a new immune-associated long non-coding RNA (lncRNA) signature to predict the prognosis of Ewing sarcoma (ES) and explore its molecular mechanisms. We downloaded transcriptome and clinical prognosis data from th
Externí odkaz:
https://doaj.org/article/f683146962a34f1a8b39c8e1f2d37aeb
Publikováno v:
Diagnostics, Vol 10, Iss 3, p 171 (2020)
This study aimed to find potential diagnostic markers for osteoarthritis (OA) and analyze the role of immune cells infiltration in this pathology. We used OA datasets from the Gene Expression Omnibus database. First, R software was used to identify d
Externí odkaz:
https://doaj.org/article/2dca875ec0f94d5486524154314492b5
Autor:
Chun-mei Shen, Bo-feng Zhu, Ya-jun Deng, Shi-hui Ye, Jiang-wei Yan, Guang Yang, Hong-dan Wang, Hai-xia Qin, Qi-zhao Huang, Jing-Jing Zhang
Publikováno v:
PLoS ONE, Vol 5, Iss 11, p e13458 (2010)
BackgroundPrevious studies indicate that the frequency distributions of HLA alleles and haplotypes vary from one ethnic group to another or between the members of the same ethnic group living in different geographic areas. It is necessary and meaning
Externí odkaz:
https://doaj.org/article/e3cde981265f40f48a238d5cf89109e6
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Autor:
Guang-Zhi Zhang, Hai-Wei Chen, Ya-jun Deng, Ming-Qiang Liu, Zuo-Long Wu, Zhan-Jun Ma, Xue-Gang He, Yi-Cheng Gao, Xue-Wen Kang
Publikováno v:
Oxidative Medicine and Cellular Longevity. 2022:1-27
Intervertebral disc degeneration (IDD) is the most common chronic skeletal muscle degeneration disease. Although the underlying mechanisms remain unclear, nucleus pulposus (NP) autophagy, senescence, and apoptosis are known to play a critical role in
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-13 (2020)
Scientific Reports
Scientific Reports
Immune-related genes (IRGs) are responsible for osteosarcoma (OS) initiation and development. We aimed to develop an optimal IRGs-based signature to assess of OS prognosis. Sample gene expression profiles and clinical information were downloaded from