Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Ya-cen Hu"'
Autor:
Hong-xu Pan, Yu-wen Zhao, Jun-pu Mei, Zheng-huan Fang, Yige Wang, Xun Zhou, Yang-jie Zhou, Rui Zhang, Kai-lin Zhang, Li Jiang, Qian Zeng, Yan He, Zheng Wang, Zhen-hua Liu, Qian Xu, Qi-ying Sun, Yang Yang, Ya-cen Hu, Ya-se Chen, Juan Du, Li-fang Lei, Hai-nan Zhang, Chun-yu Wang, Xin-xiang Yan, Lu Shen, Hong Jiang, Jie-qiong Tan, Jin-chen Li, Bei-sha Tang, Ji-feng Guo
Publikováno v:
Translational Neurodegeneration, Vol 9, Iss 1, Pp 1-12 (2020)
Abstract Background Common and rare variants of guanosine triphosphate cyclohydrolase 1 (GCH1) gene may play important roles in Parkinson’s disease (PD). However, there is a lack of comprehensive analysis of GCH1 genotypes, especially in non-coding
Externí odkaz:
https://doaj.org/article/e37c50f7cbe541038d65d3dfff802d0e
Autor:
Hong-Xu Pan, Zhao, Yu-Wen, Jun-Pu Mei, Zheng-Huan Fang, Yige Wang, Zhou, Xun, Yang-Jie Zhou, Zhang, Rui, Zhang, Kai-Lin, Jiang, Li, Zeng, Qian, He, Yan, Wang, Zheng, Liu, Zhen-Hua, Xu, Qian, Qi-Ying Sun, Yang, Yang, Ya-Cen Hu, Ya-Se Chen, Du, Juan, Lei, Li-Fang, Zhang, Hai-Nan, Wang, Chun-Yu, Yan, Xin-Xiang, Shen, Lu, Jiang, Hong, Jie-Qiong Tan, Jin-Chen Li, Bei-Sha Tang, Guo, Ji-Feng
Additional file 5 Table S5. Coding variants of GCH1 identified in two cohorts.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2173627390b33ce1f4841c1a72f738ea
Autor:
Hong-Xu Pan, Zhao, Yu-Wen, Jun-Pu Mei, Zheng-Huan Fang, Yige Wang, Zhou, Xun, Yang-Jie Zhou, Zhang, Rui, Zhang, Kai-Lin, Jiang, Li, Zeng, Qian, He, Yan, Wang, Zheng, Liu, Zhen-Hua, Xu, Qian, Qi-Ying Sun, Yang, Yang, Ya-Cen Hu, Ya-Se Chen, Du, Juan, Lei, Li-Fang, Zhang, Hai-Nan, Wang, Chun-Yu, Yan, Xin-Xiang, Shen, Lu, Jiang, Hong, Jie-Qiong Tan, Jin-Chen Li, Bei-Sha Tang, Guo, Ji-Feng
Additional file 1 Table S1. Targeted GCH1 regions and variants included in the study.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f725669649010fcfe1070d7ed8fd4a7
Autor:
Hong-Xu Pan, Zhao, Yu-Wen, Jun-Pu Mei, Zheng-Huan Fang, Yige Wang, Zhou, Xun, Yang-Jie Zhou, Zhang, Rui, Zhang, Kai-Lin, Jiang, Li, Zeng, Qian, He, Yan, Wang, Zheng, Liu, Zhen-Hua, Xu, Qian, Qi-Ying Sun, Yang, Yang, Ya-Cen Hu, Ya-Se Chen, Du, Juan, Lei, Li-Fang, Zhang, Hai-Nan, Wang, Chun-Yu, Yan, Xin-Xiang, Shen, Lu, Jiang, Hong, Jie-Qiong Tan, Jin-Chen Li, Bei-Sha Tang, Guo, Ji-Feng
Additional file 2 Table S2. The quality control of the targeted GCH1 regions.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6864e94370c71aab4ca2ee5d442b6a31
Autor:
Hong-Xu Pan, Zhao, Yu-Wen, Jun-Pu Mei, Zheng-Huan Fang, Yige Wang, Zhou, Xun, Yang-Jie Zhou, Zhang, Rui, Zhang, Kai-Lin, Jiang, Li, Zeng, Qian, He, Yan, Wang, Zheng, Liu, Zhen-Hua, Xu, Qian, Qi-Ying Sun, Yang, Yang, Ya-Cen Hu, Ya-Se Chen, Du, Juan, Lei, Li-Fang, Zhang, Hai-Nan, Wang, Chun-Yu, Yan, Xin-Xiang, Shen, Lu, Jiang, Hong, Jie-Qiong Tan, Jin-Chen Li, Bei-Sha Tang, Guo, Ji-Feng
Additional file 3 Table S3. Association analysis of common non-coding variants identified in this study.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1647ec5c808b878b3d736277cb95ba1b
Autor:
Ji-Feng, Guo, Shuang, He, Ji-Feng, Kang, Qian, Xu, Ya-Cen, Hu, Hai-Nan, Zhang, Chun-Yu, Wang, Xin-Xiang, Yan, Bei-Sha, Tang
Publikováno v:
International journal of clinical and experimental medicine. 8(10)
Rasagiline, a novel monoamine oxidase (MAO)-B inhibitor, has a mild to moderate effect in relieving Parkinson’s disease (PD) symptoms as well as unique neuroprotective effects. Previous studies demonstrated rasagiline protect neurons by regulating