Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Ya-Yue Gao"'
Publikováno v:
Frontiers in Genetics, Vol 14 (2023)
Background: For prediction on leukemic transformation of MDS patients, emerging model based on transcriptomic datasets, exhibited superior predictive power to traditional prognostic systems. While these models were lack of external validation by inde
Externí odkaz:
https://doaj.org/article/163e94ecc7aa453eb43e6b9f152d7047
The landscape of gene co-expression modules correlating with prognostic genetic abnormalities in AML
Publikováno v:
Journal of Translational Medicine, Vol 19, Iss 1, Pp 1-18 (2021)
Abstract Background The heterogenous cytogenetic and molecular variations were harbored by AML patients, some of which are related with AML pathogenesis and clinical outcomes. We aimed to uncover the intrinsic expression profiles correlating with pro
Externí odkaz:
https://doaj.org/article/f6632b0fa04b4cdda3a02cf5e5081157
Publikováno v:
Journal of Translational Medicine, Vol 19, Iss 1, Pp 1-13 (2021)
Abstract Background The transcriptomic signature has not been fully elucidated in PV, as well as mRNA markers for clinical variables (thrombosis, leukemic transformation, survival, etc.). We attempted to reveal and validate crucial co-expression modu
Externí odkaz:
https://doaj.org/article/7dba996b7aa149d2832a331f56efddaa
Publikováno v:
Journal of Translational Medicine, Vol 19, Iss 1, Pp 1-19 (2021)
Abstract Background IGHV mutation status is a crucial prognostic biomarker for CLL. In the present study, we investigated the transcriptomic signatures associating with IGHV mutation status and CLL prognosis. Methods The co-expression modules and hub
Externí odkaz:
https://doaj.org/article/38b2294bfcca44a0b775fdebfff57c8f
Publikováno v:
BMC Cancer, Vol 20, Iss 1, Pp 1-20 (2020)
Abstract Background Long noncoding RNAs (lncRNA) play a role in leukemogenesis, maintenance, development, and therapeutic resistance of AML. While few studies have focused on the prognostic significance of LINC00649 in AML, which we aim to investigat
Externí odkaz:
https://doaj.org/article/4020101bb43a49feb3dfeab7a6f319b5
Publikováno v:
BMC Cancer, Vol 20, Iss 1, Pp 1-12 (2020)
Abstract Background HOXA family genes were crucial transcription factors involving cell proliferation and apoptosis. While few studies have focused on HOXA10 in AML. We aimed to investigate the prognostic significance of HOXA10. Methods We downloaded
Externí odkaz:
https://doaj.org/article/5314e279535d453bbb3d27c6382de41a
Publikováno v:
BMC Cancer, Vol 20, Iss 1, Pp 1-20 (2020)
BMC Cancer
BMC Cancer
Background Long noncoding RNAs (lncRNA) play a role in leukemogenesis, maintenance, development, and therapeutic resistance of AML. While few studies have focused on the prognostic significance of LINC00649 in AML, which we aim to investigate in this
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::022b96a5a022ecfeacc8ca461852b10f
http://link.springer.com/article/10.1186/s12885-020-07331-0
http://link.springer.com/article/10.1186/s12885-020-07331-0
The landscape of gene co-expression modules correlating with prognostic genetic abnormalities in AML
Publikováno v:
Journal of Translational Medicine, Vol 19, Iss 1, Pp 1-18 (2021)
Journal of Translational Medicine
Journal of Translational Medicine
Background The heterogenous cytogenetic and molecular variations were harbored by AML patients, some of which are related with AML pathogenesis and clinical outcomes. We aimed to uncover the intrinsic expression profiles correlating with prognostic g
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::51e987b75f2004cd10241773841c3bb2
https://doi.org/10.1186/s12967-021-02914-2
https://doi.org/10.1186/s12967-021-02914-2
Publikováno v:
Journal of Translational Medicine
Journal of Translational Medicine, Vol 19, Iss 1, Pp 1-13 (2021)
Journal of Translational Medicine, Vol 19, Iss 1, Pp 1-13 (2021)
Background The transcriptomic signature has not been fully elucidated in PV, as well as mRNA markers for clinical variables (thrombosis, leukemic transformation, survival, etc.). We attempted to reveal and validate crucial co-expression modules and m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f0913d9419bf8146d61215bef95de77
https://pubmed.ncbi.nlm.nih.gov/34059095
https://pubmed.ncbi.nlm.nih.gov/34059095
Publikováno v:
Journal of Translational Medicine, Vol 19, Iss 1, Pp 1-19 (2021)
Journal of Translational Medicine
Journal of Translational Medicine
Background IGHV mutation status is a crucial prognostic biomarker for CLL. In the present study, we investigated the transcriptomic signatures associating with IGHV mutation status and CLL prognosis. Methods The co-expression modules and hub genes co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be74b80999e9bbbbdb1763f46638d9db
https://doi.org/10.1186/s12967-021-02708-6
https://doi.org/10.1186/s12967-021-02708-6