Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Ya-Xi Ye"'
Autor:
Wei-Yi Li, Wei-Wei Ni, Ya-Xi Ye, Hai-Lian Fang, Xing-Ming Pan, Jie-Ling He, Tian-Li Zhou, Juan Yi, Shan-Shan Liu, Mi Zhou, Zhu-Ping Xiao, Hai-Liang Zhu
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 35, Iss 1, Pp 404-413 (2020)
A urease inhibitor with good in vivo profile is considered as an alternative agent for treating infections caused by urease-producing bacteria such as Helicobacter pylori. Here, we report a series of N-monosubstituted thioureas, which act as effectiv
Externí odkaz:
https://doaj.org/article/46ee8c1b878b47fab662289f854e233b
Autor:
Ya-Xi Ye, Jian-Cheng Pan, Xin-Yue Chen, Li Jiang, Qing-Cai Jiao, Hai-Liang Zhu, Jun-Zhong Liu, Zhong-Chang Wang
Publikováno v:
The Analyst. 147:3534-3541
As a precursor of all reactive oxygen species (ROS), superoxide anions play an important role in organisms. However, excessive superoxide anions can cause various diseases. Thus, it is highly urgent to develop efficient tools for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b88e734ccc6e2f121b56030b208cf510
https://doi.org/10.1039/d2an00690a
https://doi.org/10.1039/d2an00690a
Autor:
Zhu-Ping Xiao, Hui Ouyang, Hai-Liang Zhu, Hai-Lian Fang, Li Fang, Ya-Xi Ye, Dawalamu, Fu Zijuan, Wei-Yi Li, Ke Li, Zhu Wenyan, Wei-Wei Ni, Zou Xia, Li Liu
Publikováno v:
Medicinal Chemistry. 17:1046-1059
Background: Thiourea is a classical urease inhibitor which is usually used as a positive control, and many N,N'-disubstituted thioureas have been determined as urease inhibitors. However, due to steric hindrance, N,N'-disubstituted thiourea motif cou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::86d27b5703487b10fb5996113d4e5af4
https://doi.org/10.2174/1573406416999200818152440
https://doi.org/10.2174/1573406416999200818152440
Autor:
Zhu-Min Xu, Qingcai Jiao, Xin-Yue Chen, Hai-Liang Zhu, Zhong-Chang Wang, Ya-Wen Yu, Bao-Zhong Wang, Ya-Xi Ye
Publikováno v:
New Journal of Chemistry. 45:19073-19081
As essential biological thiols in organisms, Cys, Hcy, and GSH are closely related to each other, and they can be involved in various pathological processes if expression levels are abnormal. It is a challenge to develop effective fluorescence-based
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::780311edbdd533e1b3ca93cf33659c79
https://doi.org/10.1039/d1nj03701c
https://doi.org/10.1039/d1nj03701c
Autor:
Qing Zhang, Qing-Cai Jiao, Zhong-Chang Wang, Xin-Yue Chen, Hai-Liang Zhu, Ya-Wen Yu, Xiao-Wen Wei, Ya-Xi Ye, Bao-Zhong Wang
Publikováno v:
The Analyst. 146:6556-6565
Most of the ONOO- fluorescent probes have restricted applications because of their aggregation-caused quenching (ACQ) effect, long response time and low fluorescence enhancement. Herein, we developed a novel AIEgen fluorescent probe (PE-XY) based on
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::735544ee2a49ed95017fe4ff407e5438
https://doi.org/10.1039/d1an01374b
https://doi.org/10.1039/d1an01374b
Autor:
Shi-Jia Mao, Zhu-Ping Xiao, Wei-Wei Ni, Qi-Hui Zhu, Hai-Liang Zhu, Chu-Ping Yuan, Su-E Li, Ya-Xi Ye, Wei-Yi Li, Hai-Lian Fang, Hui Ouyang, Dong-Dong Li
Publikováno v:
Future Medicinal Chemistry. 12:1633-1645
Background: Identification of novel Ure inhibitors with high potency has received considerable attention. Methodology & results: Ure inhibition was determined using the indophenol method, the affinities to Ure were estimated via surface plasmon reson
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::91d3d4fdca05b8deb44087e0f20d3b5a
https://doi.org/10.4155/fmc-2020-0048
https://doi.org/10.4155/fmc-2020-0048
Autor:
Zhu-Ping Xiao, Wan-Qing Song, Su-Ya Li, Hai-Lian Fang, Mei-Ling Liu, Hui Ouyang, Wei-Yi Li, Hai-Liang Zhu, Ya-Xi Ye
Publikováno v:
ChemMedChem. 17
Thirty-eight disulfides containing N-arylacetamide were designed and synthesized in an effort to develop novel urease inhibitors. Biological evaluation revealed that some of the synthetic compounds exhibited strong inhibitory potency against both cel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6756dd4ccd7784130d27b42f27fc20b9
https://doi.org/10.1002/cmdc.202100618
https://doi.org/10.1002/cmdc.202100618
Autor:
Song‐Yu Wu, Ya‐Xi Ye, Qing Zhang, Qian‐Jin Kang, Zhu‐Min Xu, Shen‐Zhen Ren, Fan Lin, Yong‐Tao Duan, Hao‐Jun Xu, Zi‐Yi Hu, Sui‐Sui Yang, Hai‐Liang Zhu, Mei‐Juan Zou, Zhong‐Chang Wang
Publikováno v:
Advanced Science. 10:2203742
Photodynamic therapy (PDT) under hypoxic conditions and drug resistance in chemotherapy are perplexing problems in anti-tumor treatment. In addition, central nervous system neoplasm-targeted nanoplatforms are urgently required. To address these issue
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53ccaa5862958d4dcf58688c71fbe4e7
https://doi.org/10.1002/advs.202203742
https://doi.org/10.1002/advs.202203742
Autor:
Zhu-Min Xu, Qingcai Jiao, Guan Jing, Hai-Liang Zhu, Shang-Ming-Zhu Zeng, Bao-Zhong Wang, Ya-Wen Yu, Zhong-Chang Wang, Xin-Yue Chen, Ya-Xi Ye
Publikováno v:
Talanta. 235
Bone metastasis of malignant solid tumors has become one of the most serious complications, especially in breast cancer, which was particularly challenging for early detection and treatment in clinical practice. In this work, we reported a new fluore
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f17315f2a98689444f79153c8341892
https://pubmed.ncbi.nlm.nih.gov/34517654
https://pubmed.ncbi.nlm.nih.gov/34517654
Autor:
Ya-Xi Ye, Ya-Wen Yu, Zhu-Min Xu, Xin-Yue Chen, Zhong-Chang Wang, Bao-Zhong Wang, Qing-Cai Jiao, Hai-Liang Zhu
Publikováno v:
New Journal of Chemistry. 46:10974-10974
Correction for ‘A highly selective AIEgen fluorescent probe for visualizing Cys in living cells and C. elegans’ by Ya-Xi Ye et al., New J. Chem., 2021, 45, 19073–19081.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1dcf4d946e54442478e5c84d3f84f4d6
https://doi.org/10.1039/d2nj90073d
https://doi.org/10.1039/d2nj90073d