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Akademický článek

Dynamic regulation of small RNAome during the early stage of cardiac differentiation from pluripotent embryonic stem cells

Autor: Yue Li, An Zeng, Ge Li, Ya-Na Guan, Huang-Tian Yang, Bairong Shen, Qing Jing

Publikováno v: Genomics Data, Vol 12, Iss C, Pp 136-145 (2017)

Embryonic stem cells (mESCs), having potential to differentiate into three germ-layer cells including cardiomyocytes, shall be a perfect model to help understanding heart development. Here, using small RNA deep sequencing, we studied the small RNAome

Externí odkaz: https://doaj.org/article/eed83a68d40e415a8232a9e919299507

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Akademický článek

Rapamycin and CHIR99021 Coordinate Robust Cardiomyocyte Differentiation From Human Pluripotent Stem Cells Via Reducing p53‐Dependent Apoptosis

Autor: Xiao‐Xu Qiu, Yang Liu, Yi‐Fan Zhang, Ya‐Na Guan, Qian‐Qian Jia, Chen Wang, He Liang, Yong‐Qin Li, Huang‐Tian Yang, Yong‐Wen Qin, Shuang Huang, Xian‐Xian Zhao, Qing Jing

Publikováno v: Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 6, Iss 10 (2017)

BackgroundCardiomyocytes differentiated from human pluripotent stem cells can serve as an unexhausted source for a cellular cardiac disease model. Although small molecule–mediated cardiomyocyte differentiation methods have been established, the dif

Externí odkaz: https://doaj.org/article/4e47152308b541ad9f58d4971609ea30

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Single-cell transcriptomics of murine mural cells reveals cellular heterogeneity

Autor: Qing Jing, Yue Li, Ya-Na Guan, Moom R. Roosan

Publikováno v: Science China. Life Sciences

Mural cells (MCs) wrap around the endothelium, and participate in the development and homeostasis of vasculature. MCs have been reported as heterogeneous population morphologically and functionally. However, the transcriptional heterogeneity of MCs w

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e951c91d3aaa0c430e7883fad52ba3c9
http://europepmc.org/articles/PMC7649565

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Rapamycin and CHIR99021 Coordinate Robust Cardiomyocyte Differentiation From Human Pluripotent Stem Cells Via Reducing p53‐Dependent Apoptosis

Autor: Qing Jing, Yong-wen Qin, Xiao-Xu Qiu, Qian‐Qian Jia, Chen Wang, Yong-Qin Li, Huang-Tian Yang, Yang Liu, He Liang, Xianxian Zhao, Zhang Yifan, Shuang Huang, Ya-Na Guan

Publikováno v: Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease

Background Cardiomyocytes differentiated from human pluripotent stem cells can serve as an unexhausted source for a cellular cardiac disease model. Although small molecule–mediated cardiomyocyte differentiation methods have been established, the di

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45b08ea8541ecbd601353020fa586988
https://doi.org/10.1161/jaha.116.005295

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