Zobrazeno 1 - 10
of 65
pro vyhledávání: '"Ya-Min Fu"'
Autor:
Jin Woo Kim, Yong Hee Hong, Ya-Min Fu, Jinkyu Suk, Jeong Keun Ahn, Seungkyung Yang, Jae Hoon Chung, Cheol O. Joe, Hyesun Min, Sang Su Kwak, Ji Hye Choi, Dong Hwan Lee, Gary G. Meadows, Seonghyang Sohn
Publikováno v:
Autophagy. 7:1323-1334
Tetrahydrobiopterin (BH₄) deficiency is a genetic disorder associated with a variety of metabolic syndromes such as phenylketonuria (PKU). In this article, the signaling pathway by which BH₄ deficiency inactivates mTORC1 leading to the activation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::efa8257563736baffebd881777de4683
https://doi.org/10.4161/auto.7.11.16627
https://doi.org/10.4161/auto.7.11.16627
Autor:
Xiaoyi Liu, William F. Siems, Gary G. Meadows, Ya-Min Fu, Huimin Lin, Herbert H. Hill, Kimberly Kaplan
Publikováno v:
International Journal for Ion Mobility Spectrometry. 14:151-158
Detecting early stages of cancer has been a challenge for analytical methods. Even with the advances in mammography and prostate specific antigen (PSA) testing the number of false positives and negatives is still significant. Cancer cell lines provid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bb969bad0af4c372b583d01a80f0075e
https://doi.org/10.1007/s12127-011-0066-9
https://doi.org/10.1007/s12127-011-0066-9
Publikováno v:
Journal of Cellular Physiology. 209:522-534
Relative specific amino acid dependency is one of the metabolic abnormalities of cancer cells, and restriction of specific amino acids induces apoptosis of prostate cancer cells. This study shows that restriction of tyrosine and phenylalanine (Tyr/Ph
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b8e99f9858fd68c6c8e28e77696dad38
https://doi.org/10.1002/jcp.20766
https://doi.org/10.1002/jcp.20766
Publikováno v:
Nutrition and Cancer. 45:60-73
Androgen-independent prostate cancer is resistant to therapy and is often metastatic. Here we studied the effect of deprivation of tyrosine and phenylalanine (Tyr/Phe), glutamine (Gln), or methionine (Met), in vitro on human DU145 and PC3 androgen-in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eab61354ee62fda593098de5af88df3f
https://doi.org/10.1207/s15327914nc4501_8
https://doi.org/10.1207/s15327914nc4501_8
Publikováno v:
Archives of Biochemistry and Biophysics. 403:50-58
Deprivation of tyrosine (Tyr) and phenylalanine (Phe) inhibits growth and induces programmed cell death (apoptosis) of human A375 melanoma cells. Herein, we found that activation of caspases and release of mitochondrial cytochrome c are required for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c382910edd5c169211ec4a81cb76ec0
https://doi.org/10.1016/s0003-9861(02)00211-4
https://doi.org/10.1016/s0003-9861(02)00211-4
Publikováno v:
Cancer Letters. 179:133-140
The anti-invasive ability of the mitogen-activated protein kinase (MAPK) kinase inhibitor, U0126, was examined in human A375 melanoma cells in vitro. The effect was compared to that of PD98059, another commonly used MEK (MAPK kinase) inhibitor. U0126
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::82bbc101cb00615316dd04e07eccb0ca
https://doi.org/10.1016/s0304-3835(02)00004-6
https://doi.org/10.1016/s0304-3835(02)00004-6
Publikováno v:
Clinical and Experimental Metastasis. 17:841-848
We previously found that dietary tyrosine (Tyr) and phenylalanine (Phe) limitation significantly decreased the metastatic phenotype of B16BL6 melanoma cells in vivo and decreased the in vitro invasion of these cells. To more specifically characterize
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5b3186b2a9338a14fd50f164212f7619
https://doi.org/10.1023/a:1006713000684
https://doi.org/10.1023/a:1006713000684
Publikováno v:
Nutrition and Cancer. 31:1-7
Previous research in animals supports the use of tyrosine and phenylalanine (Tyr-Phe) restriction as an adjuvant to the treatment of cancer. In this regard, dietary restriction of Tyr-Phe specifically inhibits the growth of B16BL6 melanoma tumors, dr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::21bde7de44d2991403d74e3b9312a9d5
https://doi.org/10.1080/01635589809514671
https://doi.org/10.1080/01635589809514671
Publikováno v:
Nutrition and Cancer. 29:104-113
Tyr-Phe and Met limitation in vitro inhibited cell proliferation and proliferating cell nuclear antigen (PCNA) expression to a greater extent than serum limitation. Tyr-Phe and serum limitation arrested cells in the G0/G1 phase; Met limitation blocke
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b43647120ee0ab2257f7504cdb60f72c
https://doi.org/10.1080/01635589709514610
https://doi.org/10.1080/01635589709514610
Autor:
Zu-Xi Yu, Ya-Min Fu, Juan A. Sanchez, S. Biro, Ward Casscells, J. Sasse, Victor J. Ferrans, Georgeann Smale
Publikováno v:
Circulation Research. 74:485-494
Migration of endothelial cells is involved in normal and pathological angiogenesis and in re-endothelialization after vascular injury or rupture of atherosclerotic plaques. Several types of endothelial cells are known to synthesize basic fibroblast g
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f58f12408a628e32127a4ef573a54b55
https://doi.org/10.1161/01.res.74.3.485
https://doi.org/10.1161/01.res.74.3.485