Zobrazeno 1 - 10
of 41
pro vyhledávání: '"Ya-Jui Lin"'
Autor:
Ian Yi-Feng Chang, Hong-Chieh Tsai, Chia-Hua Chen, Hsiu-Chi Chen, Chia-Wen Huang, Gerald F. Cox, Fang-Min Huang, You-Yu Lin, Ko-Ting Chen, Ya-Jui Lin, Kuo-Chen Wei
Publikováno v:
Biomedical Journal, Vol 47, Iss 4, Pp 100660- (2024)
Background: A previous phase 1 dose-escalation study in Taiwan indicated CAN008 (asunercept) with standard concurrent chemoradiotherapy (CCRT) improved progression-free survival (PFS) in newly diagnosed glioblastoma (GBM) patients. This study evaluat
Externí odkaz:
https://doaj.org/article/478a8b15ce1943c2bbd16b97d38fbb54
Autor:
Kuo-Chen Wei, Peng-Wei Hsu, Hong-Chieh Tsai, Ya-Jui Lin, Ko-Ting Chen, Cheng-Hong Toh, Hui-Lin Huang, Shih-Ming Jung, Chen-Kan Tseng, Yu-Xiong Ke
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-9 (2021)
Abstract Asunercept (company code APG101 [Apogenix AG]; company code CAN008 [CANbridge Pharmaceuticals]) is a novel glycosylated fusion protein that has shown promising effectiveness in glioblastoma. This Phase I study was initiated to evaluate the t
Externí odkaz:
https://doaj.org/article/d501aa7e69be4d63a4d750756a6e13e8
Autor:
Ying-Ching Li, Ching-Chang Chen, Chun-Ting Chen, Po-Hsun Tu, Mun-Chun Yeap, Yi-Ming Wu, Zhuo-Hao Liu, Ting-Wei Chang, Ya-Jui Lin, Tai-Wei Erich Wu, Po-Chuan Hsieh
Publikováno v:
Frontiers in Surgery, Vol 9 (2022)
ObjectiveDelayed progressive mass effect (DPME) after securing an aneurysm is uncommon following microsurgical or endovascular repair and leads to a poor clinical outcome. Patients with ruptured middle cerebral artery (MCA) aneurysms have a high risk
Externí odkaz:
https://doaj.org/article/5958d52736574788b9c9d8c4eabd8bfd
Autor:
Peidong Liu, Yu Li, Yiming Zhang, John Choi, Jinhao Zhang, Guanjie Shang, Bailiang Li, Ya-Jui Lin, Laura Saleh, Liang Zhang, Li Yi, Shengping Yu, Michael Lim, Xuejun Yang
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
Gliomas are the most common primary brain cancer. While it has been known that calcium-related genes correlate with gliomagenesis, the relationship between calcium-related genes and glioma prognosis remains unclear. We assessed TCGA datasets of mRNA
Externí odkaz:
https://doaj.org/article/e1549ed7dd6b43799a4741fd523ba61f
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Gliomas are intrinsic brain tumors that originate from glial cells. Glioblastoma (GBM) is the most aggressive glioma type and resistant to immunotherapy, mainly due to its unique immune environment. Dimensional data analysis reveals that the intra-tu
Externí odkaz:
https://doaj.org/article/36909abcaff34c5da700ca5aa3f64833
Autor:
Sheng-Han Huang, Chun-Chieh Wang, Kuo-Chen Wei, Cheng-Nen Chang, Chi-Cheng Chuang, Hsien-Chih Chen, Ya-Jui Lin, Ko-Ting Chen, Ping-Ching Pai, Peng-Wei Hsu
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-10 (2020)
Abstract Single-session stereotactic radiosurgery (SSRS) is recognized as a safe and efficient treatment for meningioma. We aim to compare the long-term efficacy and safety of fractionated stereotactic radiotherapy (FSRT) with SSRS in the treatment o
Externí odkaz:
https://doaj.org/article/6e243e376bd4419798a7d5ecfeaf0d7d
Autor:
Chun-Ting Chen, Ching-Chang Chen, Alvin Yi-Chou Wang, Yi-Ming Wu, Shy-Chyi Chin, Po-Chuan Hsieh, Mun-Chun Yeap, Shih-Yuan Hsu, Ya-Jui Lin
Publikováno v:
BMC Neurology, Vol 20, Iss 1, Pp 1-8 (2020)
Abstract Background Cerebral vasospasm still results in high morbidity and mortality rates in patients after aneurysmal subarachnoid hemorrhage (SAH). The aim of this study was to establish a protocol for the management of vasospasm and demonstrate o
Externí odkaz:
https://doaj.org/article/dba65e44d5b047c1962ae18af9a5043c
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Chimeric antigen receptor T cells (CAR T cells) are engineered cells expressing a chimeric antigen receptor (CAR) against a specific tumor antigen (TA) that allows for the identification and elimination of cancer cells. The remarkable clinical effect
Externí odkaz:
https://doaj.org/article/c9546247969d47138a0d50e6a4523a98
Autor:
Hong-Chieh Tsai, Kuo-Chen Wei, Pin-Yuan Chen, Chiung-Yin Huang, Ko-Ting Chen, Ya-Jui Lin, Hsiao-Wei Cheng, Yi-Rou Chen, Hsiang-Tsui Wang
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
Glioblastoma (GBM), the most lethal type of brain tumor in adults, has considerable cellular heterogeneity. The standard adjuvant chemotherapeutic agent for GBM, temozolomide (TMZ), has a modest response rate due to the development of drug resistance
Externí odkaz:
https://doaj.org/article/dd96ca3b041f47cdb325700f1154a79f
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Neutrophils, which are the most abundant circulating leukocytes in humans, are the first line of defense against bacterial and fungal infections. Recent studies have reported the role and importance of neutrophils in cancers. Glioma and brain metasta
Externí odkaz:
https://doaj.org/article/6abecbb2553c4d88b3b3d615ac5aace6