Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Ya-Ju Tseng"'
Autor:
Ya-Ju Tseng, 曾雅茹
97
In this works, new electroactive vinyl polymers containing conjugated segment of aniline pentamer (ANP) side chains were successful synthesized. First of all, Oligoanilines were prepared by chemical oxidative coupling reaction, followed by re
In this works, new electroactive vinyl polymers containing conjugated segment of aniline pentamer (ANP) side chains were successful synthesized. First of all, Oligoanilines were prepared by chemical oxidative coupling reaction, followed by re
Externí odkaz:
http://ndltd.ncl.edu.tw/handle/95862228124274850553
Autor:
Yung-Ning Yang, Wen-Hsing Lin, Ching-Ping Chen, Tsu Hsu, John T.A. Hsu, Weir-Torn Jiaang, Yu-Sheng Chao, Ching-Fang Yeh, Ling-Hui Chou, Chun-Hwa Chen, Teng-Kuang Yeh, Jen-Shin Song, Chiung-Tong Chen, Shu-Yi Hsieh, Cheng-Tai Lu, Ching-Hui Chiu, Shih-Chieh Yen, Ya-Ju Tseng, Kuei-Jung Yen
Publikováno v:
Bioorganic & Medicinal Chemistry. 21:2856-2867
Preclinical investigations and early clinical trials suggest that FLT3 inhibitors are a viable therapy for acute myeloid leukemia. However, early clinical data have been underwhelming due to incomplete inhibition of FLT3. We have developed 3-phenyl-1
Autor:
John T.A. Hsu, Teng-Kuang Yeh, Cheng-Tai Lu, Chun-Wha Chen, An-Huei Cheng, Chiung-Tong Chen, Yun-I Chang, Yu-Lin Huang, Ya-Ju Tseng, Kuei-Rong Yen, Shu-Yi Hsieh, Ling-Hui Chou, Yu-Sheng Chao, Tsu Hsu, Ching-Ping Chen, Shih-Chieh Yen, Wen-Hsing Lin, Weir-Torn Jiaang
Publikováno v:
Bioorganic & Medicinal Chemistry. 19:4173-4182
Preclinical investigations and early clinical trial studies suggest that FLT3 inhibitors offer a viable therapy for acute myeloid leukemia. However, early clinical data for direct FLT3 inhibitors provided only modest results because of the failure to
Autor:
Cheng-Tai Lu, Yu-Sheng Chao, Weir-Torn Jiaang, Tsu Hsu, Ting-Yueh Tsai, Mei-Chun Chiou, Ya-Ju Tseng
Publikováno v:
Journal of the Chinese Chemical Society. 58:108-117
A novel five-step synthesis of Boc-3,3-dimethylglutamic acid α-ethyl ester 11 is reported. All the steps are high yielding and simple to carry out. By use of the 3,3-dimethylglutamic acid building block, we successfully discovered a novel class of D
Autor:
Weir-Torn Jiaang, Yu-Lin Huang, Yu-Sheng Chao, Yu-Wen Huang, Chih-Hsiang Huang, Hung-Kuan Tang, Jen-Shin Song, Chiung-Tong Chen, Kai-Chia Yeh, Ting-Yueh Tsai, Chung-Yu Huang, Mei-Chun Chiou, Tsu Hsu, Jai-Hong Cheng, Xin Chen, Teng-Kuang Yeh, Horng-Shing Shy, Min-Hsien Wang, Ya-Ju Tseng, Chia-Hui Chien
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 20:3596-3600
A series of 2-[3-[2-[(2S)-2-cyano-1-pyrrolidinyl]-2-oxoethylamino]-3-methyl-1-oxobutyl]-based DPP-IV inhibitors with various monocyclic amines were synthesized. The structure-activity relationships (SAR) led to the discovery of potent DPP-IV inhibito
Autor:
Weir-Torn Jiaang, Kuei-Rong Yen, Ling-Hui Chou, Wen-Hsing Lin, John T.A. Hsu, Ching-Hui Chiu, Teng-Kuang Yeh, Shih-Chieh Yen, Chiung-Tong Chen, Yun-I Chang, Shu-Yi Hsieh, Ya-Ju Tseng, Cheng-Tai Lu, Tsu Hsu, Chun-Hwa Chen, Yu-Sheng Chao
Publikováno v:
Bioorganicmedicinal chemistry letters. 22(14)
A new class of FLT3 inhibitors has been identified based on the 3-phenyl-1H-5-pyrazolylamine scaffold. The structure–activity relationships led to the discovery of two carbamate series, and some potent compounds within these two series exhibited be
Autor:
Yu-Sheng Chao, Min-Hsien Wang, Kai-Chia Yeh, Chih-Hsiang Huang, Teng-Kuang Yeh, Ya-Ju Tseng, Jai-Hong Cheng, Chung-Yu Huang, Mei-Chun Chiou, Weir-Torn Jiaang, Tsu Hsu, Ssu-Hui Wu, Chiung-Tong Chen, Ting-Yueh Tsai, Xin Chen, Yu-Wen Huang
Publikováno v:
Bioorganicmedicinal chemistry letters. 19(7)
A series of (2S)-cyanopyrrolidines with glutamic acid derivatives at the P2 site have been prepared and evaluated as inhibitors of dipeptidyl peptidase IV (DPP-IV). The structure-activity relationships (SAR) led to the discovery of potent 3-substitut