Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Ya-Di Zhu"'
Autor:
Zi-Qiang Chen, Wen-Yao He, Si-Yuan Yang, Hong-Hong Ma, Jing Zhou, Hao Li, Ya-Di Zhu, Xing-Kai Qian, Li-Wei Zou
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 39, Iss 1 (2024)
Obesity is acknowledged as a significant risk factor for various metabolic diseases, and the inhibition of human pancreatic lipase (hPL) can impede lipid digestion and absorption, thereby offering potential benefits for obesity treatment. Anthraquino
Externí odkaz:
https://doaj.org/article/6c3dd1b0a8d343bfbdecfd4f902cc30f
Autor:
Ya-Di Zhu, Hui-Lin Pang, Qi-Hang Zhou, Zi-Fei Qin, Qiang Jin, Moshe Finel, Yi-Nan Wang, Wei-Wei Qin, Yin Lu, Dan-Dan Wang, Guang-Bo Ge
Publikováno v:
Journal of Pharmaceutical Analysis, Vol 10, Iss 3, Pp 263-270 (2020)
The human UDP-glucuronosyltransferase 1A1 (UGT1A1), one of the most essential conjugative enzymes, is responsible for the metabolism and detoxification of bilirubin and other endogenous substances, as well as many different xenobiotic compounds. Deci
Externí odkaz:
https://doaj.org/article/7319b531540a498d93b4b14eb32543d8
Autor:
Hui-Lin Pang, Guang-Hao Zhu, Qi-Hang Zhou, Chun-Zhi Ai, Ya-Di Zhu, Ping Wang, Tong-Yi Dou, Yang-Liu Xia, Hong Ma, Guang-Bo Ge
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Human UDP-glucuronosyltransferase 1A1 (hUGT1A1) is one of the most essential phase II enzymes in humans. Dysfunction or strong inhibition of hUGT1A1 may result in hyperbilirubinaemia and clinically relevant drug/herb-drug interactions (DDIs/HDIs). Re
Externí odkaz:
https://doaj.org/article/6efdbc92ace844f68566251854ee9568
Autor:
Ya-Di Zhu, Xiao-Qing Guan, Jing Chen, Sheng Peng, Moshe Finel, Ying-Yuan Zhao, Rui-Min Wang, Hui-Chang Bi, Ming Lei, Dan-Dan Wang, Guang-Bo Ge
Publikováno v:
Frontiers in Pharmacology, Vol 11 (2021)
UDP-glucuronosyltransferase 1A1 (UGT1A1) is an essential enzyme in mammals that is responsible for detoxification and metabolic clearance of the endogenous toxin bilirubin and a variety of xenobiotics, including some crucial therapeutic drugs. Discov
Externí odkaz:
https://doaj.org/article/5a19f072ec1e4a7b8c798ddc099ca5f2
Autor:
Ya-Di Zhu, Gui-Lin Wei, Ming Lei, Dan-Dan Wang, Xiao-Fang Yang, Huan Geng, Lijiao You, Guang-Bo Ge
Publikováno v:
Basic & Clinical Pharmacology & Toxicology. 129:15-25
Polyphyllin I (PPI) and its analogues, including polyphyllin II (PPII), polyphyllin VI (PPVI) and polyphyllin VII (PPVII), are major bioactive compounds isolated from the Chinese herb Chonglou. However, the susceptibilities of PPI and its analogues t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f41ea77f0851248a584d882bf058761d
https://doi.org/10.1111/bcpt.13596
https://doi.org/10.1111/bcpt.13596
Autor:
Ya-Di Zhu, Peng Gao, Xiao-Qing Guan, Jian Huang, Yang Yu, Li-Wei Zou, Dan-Dan Wang, Ling Yang, Ping Wang, Guang-Bo Ge, Qiang Jin
Publikováno v:
ACS Sensors. 5:1987-1995
Discovery of novel liver injury indicators and development of practical assays to detect target indicator(s) would strongly facilitate the diagnosis of liver disorders. Herein, an alternative biomarker discovery strategy was applied to find suitable
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5df78e7859396a31f97f1bef4d8cfcd5
https://doi.org/10.1021/acssensors.0c00384
https://doi.org/10.1021/acssensors.0c00384
Autor:
Qiang Jin, Yin Lu, Zi-Fei Qin, Moshe Finel, Hui-Lin Pang, Qi-Hang Zhou, Dan-Dan Wang, Ya-Di Zhu, Yi-Nan Wang, Wei-Wei Qin, Guang-Bo Ge
Publikováno v:
Journal of Pharmaceutical Analysis
Journal of Pharmaceutical Analysis, Vol 10, Iss 3, Pp 263-270 (2020)
Journal of Pharmaceutical Analysis, Vol 10, Iss 3, Pp 263-270 (2020)
The human UDP-glucuronosyltransferase 1A1 (UGT1A1), one of the most essential conjugative enzymes, is responsible for the metabolism and detoxification of bilirubin and other endogenous substances, as well as many different xenobiotic compounds. Deci
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::23f6e98c948a32f1a97a0c597e983491
https://doi.org/10.1016/j.jpha.2020.05.005
https://doi.org/10.1016/j.jpha.2020.05.005
Autor:
Xingkai Qian, Ling Yang, Lijuan Xue, Qiang Jin, Dan-Dan Wang, Xiaoyu Wang, Guang-Bo Ge, Ya-Di Zhu
Publikováno v:
Analytical and Bioanalytical Chemistry. 412:2645-2654
Human carboxylesterase 2 (hCE2), one of the most principal drug-metabolizing enzymes, catalyzes the hydrolysis of a variety of endogenous esters, anticancer agents, and environmental toxicants. The significant roles of hCE2 in both endobiotic and xen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a8a41c1376e8d91d5ed6eb8cce21b458
https://doi.org/10.1007/s00216-020-02494-y
https://doi.org/10.1007/s00216-020-02494-y
Autor:
Wenzhi Guo, Ya-Kun Bai, Ya-Di Zhu, Fangjun Wang, Li-Rong Zhang, Qihua Zhang, Chao Huang, Tian-Ran Chen, Hai-Bin Liu, Ling-Hua Wei, Guang-Bo Ge, Cheng-Cheng Shi
Publikováno v:
RSC Advances. 10:3626-3635
Thrombin inhibition therapy is a practical strategy to reduce thrombotic and cardiovascular risks via blocking the formation of blood clots. This study aimed to identify naturally occurring thrombin inhibitors from licorice (one of the most popular e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6fa93dba4324db30f87d550f43b0636c
https://doi.org/10.1039/c9ra09203j
https://doi.org/10.1039/c9ra09203j
Autor:
Hui-Lin, Pang, Guang-Hao, Zhu, Qi-Hang, Zhou, Chun-Zhi, Ai, Ya-Di, Zhu, Ping, Wang, Tong-Yi, Dou, Yang-Liu, Xia, Hong, Ma, Guang-Bo, Ge
Publikováno v:
Frontiers in pharmacology. 13
Human UDP-glucuronosyltransferase 1A1 (hUGT1A1) is one of the most essential phase II enzymes in humans. Dysfunction or strong inhibition of hUGT1A1 may result in hyperbilirubinaemia and clinically relevant drug/herb-drug interactions (DDIs/HDIs). Re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e86d2e45f0dc322c80e64124e10d3fb8
https://pubmed.ncbi.nlm.nih.gov/35264954
https://pubmed.ncbi.nlm.nih.gov/35264954