Zobrazeno 1 - 10 of 74 pro vyhledávání: '"Ya Suo"'
1
Akademický článek
Pioglitazone Inhibits Diabetes-Induced Atrial Mitochondrial Oxidative Stress and Improves Mitochondrial Biogenesis, Dynamics, and Function Through the PPAR-γ/PGC-1α Signaling Pathway
Autor: Zhiwei Zhang, Xiaowei Zhang, Lei Meng, Mengqi Gong, Jian Li, Wen Shi, Jiuchun Qiu, Yajuan Yang, Jianping Zhao, Ya Suo, Xue Liang, Xinghua Wang, Gary Tse, Ning Jiang, Guangping Li, Yungang Zhao, Tong Liu
Publikováno v: Frontiers in Pharmacology, Vol 12 (2021)
Background: Oxidative stress contributes to adverse atrial remodeling in diabetes mellitus. This remodeling can be prevented by the PPAR-γ agonist pioglitazone via its antioxidant and anti-inflammatory effects. In this study, we examined the molecul
Externí odkaz: https://doaj.org/article/5080a93b70a64425a03ca55c6a2d4b3a
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2
Akademický článek
Intermittent hypoxia mediated by TSP1 dependent on STAT3 induces cardiac fibroblast activation and cardiac fibrosis
Autor: Qiankun Bao, Bangying Zhang, Ya Suo, Chen Liu, Qian Yang, Kai Zhang, Ming Yuan, Meng Yuan, Yue Zhang, Guangping Li
Publikováno v: eLife, Vol 9 (2020)
Intermittent hypoxia (IH) is the predominant pathophysiological disturbance in obstructive sleep apnea (OSA), known to be independently associated with cardiovascular diseases. However, the effect of IH on cardiac fibrosis and molecular events involv
Externí odkaz: https://doaj.org/article/f79e0b8e242a4caaa509b8dfdd33d81d
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3
Akademický článek
Alogliptin prevents diastolic dysfunction and preserves left ventricular mitochondrial function in diabetic rabbits
Autor: Xiaowei Zhang, Zhiwei Zhang, Yajuan Yang, Ya Suo, Ruimeng Liu, Jiuchun Qiu, Yungang Zhao, Ning Jiang, Changle Liu, Gary Tse, Guangping Li, Tong Liu
Publikováno v: Cardiovascular Diabetology, Vol 17, Iss 1, Pp 1-12 (2018)
Abstract Background There are increasing evidence that left ventricle diastolic dysfunction is the initial functional alteration in the diabetic myocardium. In this study, we hypothesized that alogliptin prevents diastolic dysfunction and preserves l
Externí odkaz: https://doaj.org/article/f711913d27074c488fea9c0dc687fcc2
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4
Akademický článek
Sacubitril/Valsartan Improves Left Atrial and Left Atrial Appendage Function in Patients With Atrial Fibrillation and in Pressure Overload-Induced Mice
Autor: Ya Suo, Meng Yuan, Hongmin Li, Yue Zhang, Ying Li, Huaying Fu, Fei Han, Changhui Ma, Yuanyuan Wang, Qiankun Bao, Guangping Li
Publikováno v: Frontiers in Pharmacology, Vol 10 (2019)
LCZ696 (sacubitril/valsartan) is an angiotensin receptor-neprilysin inhibitor and has shown beneficial effects in patients with heart failure. However, whether LCZ696 protects against left atrial (LA) and LA appendage (LAA) dysfunction is still uncle
Externí odkaz: https://doaj.org/article/d2a98a1317084a6e974f68bd6ed24c80
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6
Data from Curcumin Induces the Differentiation of Myeloid-Derived Suppressor Cells and Inhibits Their Interaction with Cancer Cells and Related Tumor Growth
Autor: Chung S. Yang, Timothy C. Wang, Anna Liu, Gang Lu, Ya Suo, Li Ming Zhu, Jin Dong Shi, Huanyu Jin, Shui Ping Tu
Myeloid-derived suppressor cells (MDSC) accumulate in the spleen and tumors and contribute to tumor growth, angiogenesis, and progression. In this study, we examined the effects of curcumin on the activation and differentiation of MDSCs, their intera
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::118b42c493b5532bf1dfef488721014d
https://doi.org/10.1158/1940-6207.c.6544809
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8
Altered profiles of fecal bile acids correlate with gut microbiota and inflammatory responses in patients with ulcerative colitis
Autor: Fei-Ya Suo, Xiao-Ran Zhu, Zhenhuan Yang, Shu-Kun Yao, Fang Liu, Zi-jun Jia
Publikováno v: World Journal of Gastroenterology
BACKGROUND Gut microbiota and its metabolites may be involved in the pathogenesis of inflammatory bowel disease. Several clinical studies have recently shown that patients with ulcerative colitis (UC) have altered profiles of fecal bile acids (BAs).
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e3a3f26e9a41899c96273b0575f903f
https://doi.org/10.3748/wjg.v27.i24.3609
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9
Angiotensin receptor-neprilysin inhibitor attenuates cardiac hypertrophy and improves diastolic dysfunction in a mouse model of heart failure with preserved ejection fraction
Autor: Yue Zhang, Meng Yuan, Ya Suo, Qian Yang, Shuai Shao, Ying Li, Yuanyuan Wang, Qiankun Bao, Tong Liu, Guangping Li
Publikováno v: Clinical and experimental pharmacologyphysiologyREFERENCES. 49(8)
LCZ696, an angiotensin receptor-neprilysin inhibitor, has shown promising clinical efficacy in patients with heart failure (HF) with reduced ejection fraction. However, its potential effects on heart failure with preserved ejection fraction (HFpEF) a
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f48fdd8c22de497a6a727388380954e
https://pubmed.ncbi.nlm.nih.gov/35596518
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10
Role of NLRP3-Inflammasome/Caspase-1/Galectin-3 Pathway on Atrial Remodeling in Diabetic Rabbits
Autor: Xianjian Liu, Daimiao Tu, Tong Liu, Ya Suo, Changle Liu, Yang Liu, Xiaohan Wu, Shulin Niu, Guangping Li
Publikováno v: Journal of Cardiovascular Translational Research. 13:731-740
Both diabetes mellitus (DM) and atrial fibrillation (AF) are usually associated with enhanced inflammatory response. The effect of the "NACHT, LRR and PYD domain containing protein 3" (NLRP3)-inflammasome/caspase-1/galectin-3 pathway and the potentia
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6fc557c1132d7f9997a982465d4bf2c2
https://doi.org/10.1007/s12265-020-09965-8
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