Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Ya Chin Hsiao"'
Autor:
Hassan Issafras, Shilong Fan, Chi-Ling Tseng, Yunchih Cheng, Peihua Lin, Lisa Xiao, Yun-Ju Huang, Chih-Hsiang Tu, Ya-Chin Hsiao, Min Li, Yen-Hsiao Chen, Chien-Hsin Ho, Ou Li, Yanling Wang, Sandra Chen, Zhenyu Ji, Eric Zhang, Yi-Ting Mao, Eugene Liu, Shumin Yang, Weidong Jiang
Publikováno v:
PLoS ONE, Vol 16, Iss 12 (2021)
Cancer immunotherapies, such as checkpoint blockade of programmed cell death protein-1 (PD-1), represents a breakthrough in cancer treatment, resulting in unprecedented results in terms of overall and progression-free survival. Discovery and developm
Externí odkaz:
https://doaj.org/article/a3e781a963104f30a142f1c9a897c0c8
Autor:
Kuo-Hsuan Chang, Chiung-Mei Chen, Chih-Hsin Lin, Wen-Teng Chang, Pei-Ru Jiang, Ya-Chin Hsiao, Yih-Ru Wu, Guey-Jen Lee-Chen
Publikováno v:
Journal of the Formosan Medical Association, Vol 116, Iss 3, Pp 197-204 (2017)
Leucine-rich repeat kinase 2 (LRRK2) is a large protein encoding multiple functional domains. Mutations within different LRRK2 domains have been considered to be involved in the development of Parkinson disease by different mechanisms. Our previous s
Externí odkaz:
https://doaj.org/article/cc623358c56a4e4c9f36a432c2ad0b6e
Autor:
I-Cheng Chen, Hsuan-Yuan Lin, Ya-Chin Hsiao, Chiung-Mei Chen, Yih-Ru Wu, Hsin-Chieh Shiau, Yu-Fang Shen, Kuo-Shiu Huang, Ming-Tsan Su, Hsiu-Mei Hsieh-Li, Guey-Jen Lee-Chen
Publikováno v:
PLoS ONE, Vol 8, Iss 9, p e73885 (2013)
Spinocerebellar ataxia type 8 (SCA8) involves the expansion of CTG/CAG repeats from the overlapping ataxin 8 opposite strand (ATXN8OS) and ataxin 8 (ATXN8) genes located on chromosome 13q21. Although being transcribed, spliced and polyadenylated in t
Externí odkaz:
https://doaj.org/article/b0c80e2631c34d639649bd877538ca8a
Autor:
Yih-Ru Wu, Kuo-Hsuan Chang, Wen-Teng Chang, Ya-Chin Hsiao, Hsuan-Chu Hsu, Pei-Ru Jiang, Yi-Chun Chen, Chih-Ying Chao, Yi-Chung Chang, Bo-Hsun Lee, Fen-Ju Hu, Wan-Ling Chen, Guey-Jen Lee-Chen, Chiung-Mei Chen
Publikováno v:
PLoS ONE, Vol 8, Iss 12, p e82001 (2013)
Genetic variants of leucine-rich repeat kinase 2 (LRRK2) were reported to alter the risk for Parkinson's disease (PD). However, the genetic spectrum of LRRK2 variants has not been clearly disclosed yet in Taiwanese population. Herein, we sequenced LR
Externí odkaz:
https://doaj.org/article/ce2116ffd7694496b9801d86947510a4
Autor:
Kuo-Hsuan Chang, Chiung-Mei Chen, Yi-Chun Chen, Ya-Chin Hsiao, Chin-Chang Huang, Hung-Chou Kuo, Hsuan-Chu Hsu, Guey-Jen Lee-Chen, Yih-Ru Wu
Publikováno v:
PLoS ONE, Vol 8, Iss 1, p e54448 (2013)
A single nucleotide polymorphism GRN rs5848 (3'UTR+78 C>T) was reported to alter the risk for frontotemporal lobar degeneration. Herein, we investigated the effect of GRN rs5848 on the risk of Parkinson's disease (PD) by genotyping 573 Taiwanese pati
Externí odkaz:
https://doaj.org/article/7ebc79be8263455380ce100e24a4bbb8
Autor:
Ke Jen Hsu, Hung Chou Kuo, Ya Chin Hsiao, Chiung Mei Chen, Chin Chang Huang, Guey Jen Lee-Chen, Chia Wen Chang, Yih Ru Wu, Hsuan Chu Hsu, Chih Hsin Lin, Guan Chiun Lee, Kuo-Hsuan Chang
Publikováno v:
Parkinsonism & Related Disorders. 51:61-66
Background Mutations in the GRN (granulin precursor) are a frequent cause of frontotemporal dementia (FTD) and other atypical parkinsonian disorders. However, the frequency of GRN mutations in Asian patients with atypical parkinsonian disorders is st
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1fd2413fb5868b811bf084338671b361
https://doi.org/10.1016/j.parkreldis.2018.02.045
https://doi.org/10.1016/j.parkreldis.2018.02.045
Autor:
Pei Ru Jiang, Yih Ru Wu, Chiung Mei Chen, Ya Chin Hsiao, Wen Teng Chang, Kuo-Hsuan Chang, Chih Hsin Lin, Guey Jen Lee-Chen
Publikováno v:
Journal of the Formosan Medical Association, Vol 116, Iss 3, Pp 197-204 (2017)
Background/purpose Leucine-rich repeat kinase 2 (LRRK2) is a large protein encoding multiple functional domains. Mutations within different LRRK2 domains have been considered to be involved in the development of Parkinson disease by different mechani
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d70230ec75fcffcf3fc4244c846b0db1
https://doi.org/10.1016/j.jfma.2016.04.009
https://doi.org/10.1016/j.jfma.2016.04.009
Autor:
Tsu Wei Wang, Yih-Ru Wu, Chih-Ying Chao, I-Cheng Chen, Hsin Yi Chang, Fen-Ju Hu, Chih-Hsin Lin, Li-Ching Lee, Yi-Tsun Chen, Ya-Chin Hsiao, Ya-Tang Chen, Hsueh Fen Juan, Chiung-Mei Chen, Guey Jen Lee-Chen
Publikováno v:
American Journal of Medical Genetics Part B: Neuropsychiatric Genetics. 156:720-729
Mutations in ATP13A2 have been reported to associate with Parkinson's disease (PD). This study investigates the contribution of genetic variants in ATP13A2 to Taiwanese PD. ATP13A2 cDNA fragments from 65 early onset PD (onset
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae44e0ccd89bd8613fc5d77756c03073
https://doi.org/10.1002/ajmg.b.31214
https://doi.org/10.1002/ajmg.b.31214
Autor:
Guey Jen Lee-Chen, Hon Chung Fung, Chih Ying Chao, Long Sun Ro, Fen Ju Hu, Yi-Chun Chen, Ya Chin Hsiao, Chiung Mei Chen, Yih Ru Wu
Publikováno v:
Clinica Chimica Acta. 411:955-958
Background Impaired ubiquitin–proteasome system function may contribute to the pathogenesis of Parkinson's disease (PD). Methods We conducted a case–control study in a cohort of 517 PD cases and 518 ethnically matched controls to investigate the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d60dea3eb557d9c7ad5efd6e97322d9
https://doi.org/10.1016/j.cca.2010.03.013
https://doi.org/10.1016/j.cca.2010.03.013
Autor:
Yih-Ru Wu, Yu-Fang Shen, Hsiu Mei Hsieh-Li, Ya-Chin Hsiao, Hsuan-Yuan Lin, Kuo-Shiu Huang, Chiung-Mei Chen, Guey Jen Lee-Chen, I-Cheng Chen, Hsin-Chieh Shiau, Ming Tsan Su
Publikováno v:
PLoS ONE, Vol 8, Iss 9, p e73885 (2013)
PLoS ONE
PLoS ONE
Spinocerebellar ataxia type 8 (SCA8) involves the expansion of CTG/CAG repeats from the overlapping ataxin 8 opposite strand (ATXN8OS) and ataxin 8 (ATXN8) genes located on chromosome 13q21. Although being transcribed, spliced and polyadenylated in t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c828c68db99b2161e64586e33a1372ad
http://europepmc.org/articles/PMC3770663?pdf=render
http://europepmc.org/articles/PMC3770663?pdf=render