Zobrazeno 1 - 10
of 461
pro vyhledávání: '"Ya‐Wen Chen"'
Publikováno v:
He huaxue yu fangshe huaxue, Vol 46, Iss 5, Pp 499-505 (2024)
Due to anthropogenic and long-term geological factors, radionuclide leakage may occur in deep geological repositories of radioactive waste when groundwater infiltrates a failed waste canister. The released radionuclides can migrate to near and far fi
Externí odkaz:
https://doaj.org/article/4f0e69ea112a4bba8609a38e9e5e4c78
Publikováno v:
Frontiers in Endocrinology, Vol 15 (2024)
BackgroundMedullary thyroid cancer (MTC) is a challenging malignancy. The survival outcome of MTC based on AJCC staging system does not render a discriminant classifier among early stages.Methods3601 MTC patients from 2000 to 2018 were identified fro
Externí odkaz:
https://doaj.org/article/4bfac1dce66c42a1bbfe5bfddbbe2ea3
Publikováno v:
Neurobiology of Disease, Vol 193, Iss , Pp 106452- (2024)
A common adverse effect of Parkinson's disease (PD) treatment is L-dopa-induced dyskinesia (LID). This condition results from both dopamine (DA)-dependent and DA-independent mechanisms, as glutamate inputs from corticostriatal projection neurons impa
Externí odkaz:
https://doaj.org/article/b1d0452a70934ee9868b26b8291109d0
Publikováno v:
Frontiers in Endocrinology, Vol 15 (2024)
BackgroundThe clinic-pathological boundary between poorly differentiated thyroid cancer (PDTC) and anaplastic thyroid cancer (ATC) is unclear due to a wide spectrum of histopathological features and the rarity of the disease. In addition to that, wit
Externí odkaz:
https://doaj.org/article/d06d5bebc66542d79a9d79db61e1764c
Autor:
Kuan-I Lee, Kai-Min Fang, Chun-Ying Kuo, Chun-Fa Huang, Shing-Hwa Liu, Jui-Ming Liu, Wei-Cheng Lai, Kai-Chih Chang, Chin-Chuan Su, Ya-Wen Chen
Publikováno v:
Current Research in Toxicology, Vol 6, Iss , Pp 100155- (2024)
Paraquat (PQ), a toxic and nonselective bipyridyl herbicide, is one of the most extensively used pesticides in agricultural countries. In addition to pneumotoxicity, the liver is an important target organ for PQ poisoning in humans. However, the mech
Externí odkaz:
https://doaj.org/article/919fbfbd22b0447fbed5ecfd7828cd81
Autor:
Fenghua Bian, Ying-Wei Lan, Shuyang Zhao, Zicheng Deng, Samriddhi Shukla, Anusha Acharya, Johnny Donovan, Tien Le, David Milewski, Matthew Bacchetta, Ahmed Emad Hozain, Yuliya Tipograf, Ya-Wen Chen, Yan Xu, Donglu Shi, Vladimir V. Kalinichenko, Tanya V. Kalin
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-20 (2023)
Abstract Pulmonary fibrosis results from dysregulated lung repair and involves multiple cell types. The role of endothelial cells (EC) in lung fibrosis is poorly understood. Using single cell RNA-sequencing we identified endothelial transcription fac
Externí odkaz:
https://doaj.org/article/4172cf00b15a40cea652b6a4294f644f
Autor:
Darren Z. Nin, Ph.D., Ya-Wen Chen, M.D., M.P.H., Carl T. Talmo, M.D., Brian L. Hollenbeck, M.D., Ruijia Niu, M.P.H., David C. Chang, Ph.D., M.P.H., M.B.A., Eric L. Smith, M.D., David Mattingly, M.D.
Publikováno v:
Arthroscopy, Sports Medicine, and Rehabilitation, Vol 5, Iss 6, Pp 100776- (2023)
Purpose: To describe the different types of arthroscopic procedures that patients undergo in the year prior to total knee arthroplasty (TKA), reveal the cost associated with these procedures, and understand the relationship between preoperative arthr
Externí odkaz:
https://doaj.org/article/31507df785804bb18354fcb358e0ccbc
Autor:
An Xu, Mo Liu, Mo-Fan Huang, Yang Zhang, Ruifeng Hu, Julian A. Gingold, Ying Liu, Dandan Zhu, Chian-Shiu Chien, Wei-Chen Wang, Zian Liao, Fei Yuan, Chih-Wei Hsu, Jian Tu, Yao Yu, Taylor Rosen, Feng Xiong, Peilin Jia, Yi-Ping Yang, Danielle A. Bazer, Ya-Wen Chen, Wenbo Li, Chad D. Huff, Jay-Jiguang Zhu, Francesca Aguilo, Shih-Hwa Chiou, Nathan C. Boles, Chien-Chen Lai, Mien-Chie Hung, Zhongming Zhao, Eric L. Van Nostrand, Ruiying Zhao, Dung-Fang Lee
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-19 (2023)
The dysregulation of the m6A epitranscriptomic networks have been reported to contribute to the development of gliomas. Here, the authors utilize induced pluripotent stem cell-derived astrocytes with a p53 mutation and demonstrate that mutant p53 upr
Externí odkaz:
https://doaj.org/article/e94f230ab56e49dfb83c91e1ccf71c9f
Autor:
Yu Onodera, Jady Liang, Yuchong Li, Bryan Griffin, Thenuka Thanabalasingam, Cong Lu, JiaYi Zhu, Mingyao Liu, Theo Moraes, Wenhua Zheng, Jasmin Khateeb, Julie Khang, Yongbo Huang, Mirjana Jerkic, Masaki Nakane, Andrew Baker, Beverley Orser, Ya-Wen Chen, Gerald Wirnsberger, Josef M. Penninger, Ori D. Rotstein, Arthur S. Slutsky, Yimin Li, Samira Mubareka, Haibo Zhang
Publikováno v:
iScience, Vol 26, Iss 8, Pp 107470- (2023)
Summary: Despite similar infection rates, COVID-19 has resulted in more deaths in men than women. To understand the underlying mechanisms behind this sex-biased difference in disease severity, we infected K18-human angiotensin converting enzyme 2 (AC
Externí odkaz:
https://doaj.org/article/1459cb9ae3c84cf384230f3fe5f1882b
Autor:
Qizhou Lian, Kui Zhang, Zhao Zhang, Fuyu Duan, Liyan Guo, Weiren Luo, Bobo Wing-Yee Mok, Abhimanyu Thakur, Xiaoshan Ke, Pedram Motallebnejad, Vlad Nicolaescu, Jonathan Chen, Chui Yan Ma, Xiaoya Zhou, Shuo Han, Teng Han, Wei Zhang, Adrian Y. Tan, Tuo Zhang, Xing Wang, Dong Xu, Jenny Xiang, Aimin Xu, Can Liao, Fang-Ping Huang, Ya-Wen Chen, Jie Na, Glenn Randall, Hung-fat Tse, Zhiwei Chen, Yin Chen, Huanhuan Joyce Chen
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-14 (2022)
Model systems to study SARS-CoV-2 infection are required to better understand the immune response. Here the authors use a lung and macrophage co-culture system by differentiation of human pluripotent stem cells to better understand the phenotype and
Externí odkaz:
https://doaj.org/article/9938f59e696a4a09b36d23579730178b