Zobrazeno 1 - 10
of 721
pro vyhledávání: '"YUTAKA YATOMI"'
Autor:
Christopher D. Green, Ryan D.R. Brown, Baasanjav Uranbileg, Cynthia Weigel, Sumit Saha, Makoto Kurano, Yutaka Yatomi, Sarah Spiegel
Publikováno v:
Molecular Metabolism, Vol 86, Iss , Pp 101971- (2024)
Objective: Hepatocellular carcinoma (HCC) is the third leading cause of cancer mortality, and its incidence is increasing due to endemic obesity. HCC is sexually dimorphic in both humans and rodents with higher incidence in males, although the mechan
Externí odkaz:
https://doaj.org/article/0d27976db3474a0b8686c16ec6a18ec0
Autor:
Baasanjav Uranbileg, Eri Sakai, Masayuki Kubota, Hideaki Isago, Masahiko Sumitani, Yutaka Yatomi, Makoto Kurano
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-13 (2024)
Abstract Mass spectrometry-based lipidomics approaches offer valuable tools for the detection and quantification of various lipid species, including sphingolipids. The present study aimed to develop a new method to simultaneously detect various sphin
Externí odkaz:
https://doaj.org/article/b216bbc5511c4397b54fee729e722fc8
Publikováno v:
Frontiers in Nephrology, Vol 4 (2024)
BackgroundTo avoid an invasive renal biopsy, noninvasive laboratory testing for the differential diagnosis of kidney diseases is a desirable goal. As sphingolipids are demonstrated to be involved in the pathogenesis of various kidney diseases, we inv
Externí odkaz:
https://doaj.org/article/2add16f4c97f4a6caf8527f0d2fa0217
Autor:
Yuji Kashiwakura, Nemekhbayar Baatartsogt, Shoji Yamazaki, Azusa Nagao, Kagehiro Amano, Nobuaki Suzuki, Tadashi Matsushita, Akihiro Sawada, Satoshi Higasa, Naoya Yamasaki, Teruhisa Fujii, Taemi Ogura, Hideyuki Takedani, Masashi Taki, Takeshi Matsumoto, Jun Yamanouchi, Michio Sakai, Masako Nishikawa, Yutaka Yatomi, Koji Yada, Keiji Nogami, Ryota Watano, Takafumi Hiramoto, Morisada Hayakawa, Nobuhiko Kamoshita, Akihiro Kume, Hiroaki Mizukami, Shizukiyo Ishikawa, Yoichi Sakata, Tsukasa Ohmori
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 27, Iss , Pp 404-414 (2022)
Adeno-associated virus (AAV) vectors are promising modalities of gene therapy to address unmet medical needs. However, anti-AAV neutralizing antibodies (NAbs) hamper the vector-mediated therapeutic effect. Therefore, NAb prevalence in the target popu
Externí odkaz:
https://doaj.org/article/b43dde9c693b47fc933baa57f7dd8461
Autor:
Takuya Shimura, Makoto Kurano, Koh Okamoto, Daisuke Jubishi, Hideki Hashimoto, Kuniyuki Kano, Koji Igarashi, Satoshi Shimamoto, Junken Aoki, Kyoji Moriya, Yutaka Yatomi
Publikováno v:
Annals of Medicine, Vol 54, Iss 1, Pp 3189-3200 (2022)
Introduction In order to identify therapeutic targets in Coronavirus disease 2019 (COVID-19), it is important to identify molecules involved in the biological responses that are modulated in COVID-19. Lysophosphatidic acids (LPAs) are involved in the
Externí odkaz:
https://doaj.org/article/33a9954239154f15806777cb1a6376fd
Autor:
Makoto Kurano, Daisuke Jubishi, Koh Okamoto, Hideki Hashimoto, Eri Sakai, Yoshifumi Morita, Daisuke Saigusa, Kuniyuki Kano, Junken Aoki, Sohei Harada, Shu Okugawa, Kent Doi, Kyoji Moriya, Yutaka Yatomi
Publikováno v:
Journal of Biomedical Science, Vol 29, Iss 1, Pp 1-18 (2022)
Abstract Background Among various complications of coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), renal complications, namely COVID-19-associated kidney injuries, are related to the mortal
Externí odkaz:
https://doaj.org/article/8068e1f7d8d34721ab51aca8725df7b4
Autor:
Kenichi Shukuya, Yoshihumi Morita, Takashi Hisasue, Yoshikazu Ono, Satoshi Tomiyasu, Makoto Kurano, Yutaka Yatomi, Masami Tanaka
Publikováno v:
Practical Laboratory Medicine, Vol 36, Iss , Pp e00328- (2023)
a) Objectives: Urinalysis is one of the most common laboratory screening tests to detect problems in the renal and urinary system; however, they cannot detect atypical cells (Atyp.Cs). The Sysmex UF-5000, a fully automated urine particle analyzer, ca
Externí odkaz:
https://doaj.org/article/aabfee3f7f0d40ae96ab01c5ce1d5e2c
Publikováno v:
Cancer Medicine, Vol 11, Iss 18, Pp 3491-3507 (2022)
Abstract Background Numerous studies have investigated the possible involvement of eicosanoids, lysophospholipids, and sphingolipids in cancer. We considered that comprehensive measurement of these lipid mediators might provide a better understanding
Externí odkaz:
https://doaj.org/article/bc25b40aa99f490182c438d1fbc8f415
Autor:
Yoshifumi Morita, Makoto Kurano, Daisuke Jubishi, Mahoko Ikeda, Koh Okamoto, Masami Tanaka, Sohei Harada, Shu Okugawa, Kyoji Moriya, Yutaka Yatomi
Publikováno v:
International Journal of Infectious Diseases, Vol 117, Iss , Pp 302-311 (2022)
Background: Acute renal injury is an important complication of coronavirus disease 2019 (COVID-19). Both COVID-19-specific mechanisms, such as damage to the renal parenchyma by direct infection, and non-specific mechanisms, such as the pre-renal inju
Externí odkaz:
https://doaj.org/article/46b602ab5e7a461cbd12e0a400c0bba0
Autor:
Koji Murakami, Tsutomu Tamada, Daisuke Saigusa, Eisaku Miyauchi, Masayuki Nara, Masakazu Ichinose, Makoto Kurano, Yutaka Yatomi, Hisatoshi Sugiura
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-11 (2022)
Abstract Since the clinical outcome of patients with sarcoidosis is still unpredictable, a good prognostic biomarker is necessary. Autotaxin (ATX) and phosphatidylserine-specific phospholipase A1 (PS-PLA1) function as main enzymes to produce lysophos
Externí odkaz:
https://doaj.org/article/3282150208ff44bdbd9b41e96e062af3