Zobrazeno 1 - 10
of 141
pro vyhledávání: '"YUNG-JEN CHUANG"'
Publikováno v:
Experimental and Molecular Pathology, Vol 140, Iss , Pp 104946- (2024)
Background: During the COVID-19 pandemic, the viral illness caused by SARS-CoV-2 spread through respiratory droplets, resulting in a global pandemic with a range of symptoms from mild to severe. Pathological inflammation posed a critical issue, yet t
Externí odkaz:
https://doaj.org/article/008c6f16a16a4e02b77289f24ead0747
Autor:
Hsiao-Huai Kuo, Kuang-Te Wang, Hsin-Hao Chen, Zih-Yin Lai, Po-Lin Lin, Yung-Jen Chuang, Lawrence Yu-Min Liu
Publikováno v:
Diabetology & Metabolic Syndrome, Vol 16, Iss 1, Pp 1-10 (2024)
Abstract Background Cancer patients with diabetes are at increased risk for cardiovascular diseases due to common risk factors and well-documented drug-associated cardiotoxicity. Sodium-glucose cotransporter-2 (SGLT2) inhibitors have shown cardiovasc
Externí odkaz:
https://doaj.org/article/15b0c016f20a429bab65a5fe49248d9c
Autor:
Wei-Chun Chang, Mei-Jen Chen, Chung-Der Hsiao, Rong-Ze Hu, Yu-Shan Huang, Yu-Fu Chen, Tsai-Hua Yang, Guan-Yi Tsai, Chih-Wei Chou, Ren-Shiang Chen, Yung-Jen Chuang, Yi-Wen Liu
Publikováno v:
PLoS ONE, Vol 18, Iss 10, p e0292858 (2023)
RationaleCilostazol, an anti-platelet phosphodiesterase-3 inhibitor used for the treatment of intermittent claudication, is known for its pleiotropic effects on platelets, endothelial cells and smooth muscle cells. However, how cilostazol impacts the
Externí odkaz:
https://doaj.org/article/0d20632904274c0293570dc626a6e767
Autor:
Chen-Fang Hsu, Hong-Ming Liu, Jinn-Jer Peir, Jiunn-Wang Liao, Kuan-Sheng Chen, Yi-Wei Chen, Yung-Jen Chuang, Fong-In Chou
Publikováno v:
Life, Vol 13, Iss 2, p 514 (2023)
Background: Osteosarcoma (OS) is the most common primary malignancy of the bone and is notoriously resistant to radiation therapy. High-dose cytotoxic chemotherapy and surgical resection have improved the survival rate and prognosis of patients with
Externí odkaz:
https://doaj.org/article/382529c8cd7e491bb1122fdef64b1860
Publikováno v:
JBMR Plus, Vol 5, Iss 2, Pp n/a-n/a (2021)
ABSTRACT Dysregulated balance between bone resorption and formation mediates the onset and progression of osteoporosis. The administration of prednisolone is known to induce osteoporosis, whereas alendronate is commonly used to reverse the process. H
Externí odkaz:
https://doaj.org/article/0e1c0675c2774773b98e71fb3fe12f2c
Autor:
Chi-Hwa Yang, Yu-Jung Yeh, Jiz-Yuh Wang, Ya-Wen Liu, Yen-Lin Chen, Hui-Wen Cheng, Chun-Mei Cheng, Yung-Jen Chuang, Chiou-Hwa Yuh, Yi-Rong Chen
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-9 (2017)
Abstract Expression of neuroendocrine-associated phosphatase (NEAP, also named as dual specificity phosphatase 26, [DUSP26]) is restricted to neuroendocrine tissues. We found that NEAP, but not its phosphatase-defective mutant, suppressed nerve growt
Externí odkaz:
https://doaj.org/article/599719b39d684782913c9df55d9b0cf0
Autor:
Chia-Chou Wu, Tsung-Han Tsai, Chieh Chang, Tian-Thai Lee, Che Lin, Irene Han-Juo Cheng, Mu-Chien Sun, Yung-Jen Chuang, Bor-Sen Chen
Publikováno v:
PLoS ONE, Vol 9, Iss 6, p e97902 (2014)
Upon injury, the direct damage and the subsequent secondary injury in the brain often result in chronic neurological disorders. Due to multifactorial nature of secondary injury and subsequent complex cellular responses, much of the underlying mechani
Externí odkaz:
https://doaj.org/article/7f952e6a452640f58f6533b812d86a1b
Autor:
Yan Yu Chen, Chun-Cheih Chao, Fu-Chen Liu, Po-Chen Hsu, Hsueh-Fen Chen, Shih-Chi Peng, Yung-Jen Chuang, Chung-Yu Lan, Wen-Ping Hsieh, David Shan Hill Wong
Publikováno v:
PLoS ONE, Vol 8, Iss 9, p e72483 (2013)
Candida albicans is responsible for a number of life-threatening infections and causes considerable morbidity and mortality in immunocompromised patients. Previous studies of C. albicans pathogenesis have suggested several steps must occur before vir
Externí odkaz:
https://doaj.org/article/82e7ee2f74ee4ba1bff608a0ce56c561
Autor:
Wei-Chang Huang, Chung-Chi Yang, I-Hui Chen, Yu-Min Lawrence Liu, Shing-Jyh Chang, Yung-Jen Chuang
Publikováno v:
PLoS ONE, Vol 8, Iss 6, p e66613 (2013)
Myocardial injury, such as myocardial infarction (MI), can lead to drastic heart damage. Zebrafish have the extraordinary ability to regenerate their heart after a severe injury. Upon ventricle resection, fibrin clots seal the wound and serve as a ma
Externí odkaz:
https://doaj.org/article/3eca9ca75deb4ef598b69b313cc1dc36
Autor:
Hau-Shien Chan, Shing-Jyh Chang, Tao-Yeuan Wang, Hung-Ju Ko, Yu-Chih Lin, Kuan-Ting Lin, Kuo-Ming Chang, Yung-Jen Chuang
Publikováno v:
PLoS ONE, Vol 7, Iss 1, p e30397 (2012)
Serine protease PRSS23 is a newly discovered protein that has been associated with tumor progression in various types of cancers. Interestingly, PRSS23 is coexpressed with estrogen receptor α (ERα), which is a prominent biomarker and therapeutic ta
Externí odkaz:
https://doaj.org/article/c41738f4d356458d979a853e3a6019be