Zobrazeno 1 - 10
of 72
pro vyhledávání: '"YUN-SEOK RHEE"'
Publikováno v:
Pharmaceutics, Vol 14, Iss 1, p 5 (2021)
Research on the development of dissolving microneedles (DMNs) has focused on bolus drug delivery, with little attention on sustained release. Here, we evaluated the sustained release, absorption pattern, and effective drug permeation of a novel donep
Externí odkaz:
https://doaj.org/article/9a6e60e0249147f28f0ec822bc4376d9
Formulation and in vitro/in vivo evaluation of chitosan-based film forming gel containing ketoprofen
Autor:
Dong-Won Oh, Ji-Hyun Kang, Hyo-Jung Lee, Sang-Duk Han, Min-Hyung Kang, Yie-Hyuk Kwon, Joon-Ho Jun, Dong-Wook Kim, Yun-Seok Rhee, Ju-Young Kim, Eun-Seok Park, Chung-Woong Park
Publikováno v:
Drug Delivery, Vol 24, Iss 1, Pp 1056-1066 (2017)
The film forming gel, adhered to skin surfaces upon application and formed a film, has an advantage onto skin to provide protection and continuous drug release to the application site. This study aimed to prepare a chitosan-based film forming gel con
Externí odkaz:
https://doaj.org/article/dd99551ebb154999ba658db637b68df0
Publikováno v:
Pharmaceutics, Vol 12, Iss 8, p 738 (2020)
In this work, modified-release solid dosage forms were fabricated by adjusting geometrical properties of solid dosage forms through hot-melt 3D extrusion (3D HME). Using a 3D printer with air pressure driving HME system, solid dosage forms containing
Externí odkaz:
https://doaj.org/article/b3cbd397f5d9404ab2b51e1b84dd4236
Publikováno v:
Asian Journal of Pharmaceutical Sciences, Vol 10, Iss 2, Pp 108-113 (2015)
The aim of this study was to design and evaluate extended-release formulations of a model drug, nicorandil, in order to achieve the desired steady-state plasma concentration of drug in vivo. Simulation was employed to estimate optimum dissolution and
Externí odkaz:
https://doaj.org/article/8b880900a5814d718ae88d8665b6276d
Publikováno v:
International Journal of Nanomedicine, Vol 2009, Iss default, Pp 299-319 (2009)
Heidi M Mansour, Yun-Seok Rhee, Xiao WuUniversity of Kentucky, College of Pharmacy, Division of Pharmaceutical Sciences-Drug Development Division, Lexington, KY, USAAbstract: The lung is an attractive target for drug delivery due to noninvasive admin
Externí odkaz:
https://doaj.org/article/ff97a35e4408448295ebd08459f80133
Autor:
Jaemin Lee, Yun-Seok Rhee
Publikováno v:
Journal of Pharmaceutical Investigation. 52:161-173
Autor:
Dae Hwan Shin, Ju-Young Kim, Chun-Woong Park, Jinmann Chon, Ji Hyun Kang, Chang-Soo Han, Yun Seok Rhee, Myung Hee Chun, Dong-Wook Kim, Dong-Won Oh
Publikováno v:
Drug Development and Industrial Pharmacy. 47:685-693
As an active pharmaceutical ingredient, dapagliflozin propanediol monohydrate (D-PD) has been used in the solvated form consisting of dapagliflozin compounded with (S)-propylene glycol and monohydrate at a 1:1:1 ratio. However, dapagliflozin propaned
Autor:
Chun-Woong Park, Dae Hwan Shin, Jin-Hyuk Jeong, Eun-Seok Park, Yun-Seok Rhee, Yong-Bin Kwon, Hong-Goo Lee, Ju-Young Kim, Yun-Sang Park, Dong-Wook Kim
Publikováno v:
Drug Design, Development and Therapy. 13:2459-2474
Introduction: In this study, a dual release bi-layer tablet containing Fesoterodine fumarate (Fst) 5 mg and Mirabegron (Mrb) 50 mg was prepared to investigate the different release behavior of each drug in bilayer tablet. The bilayer tablet was prepa
Autor:
Yong-Bin Kwon, Dae Hwan Shin, Ju-Young Kim, Yun-Seok Rhee, Chun-Woong Park, Hyo-Jung Lee, Dong-Won Oh, Dong-Wook Kim, Ji-Hyun Kang, Eun-Seok Park
Publikováno v:
Journal of controlled release : official journal of the Controlled Release Society. 329
The conventional treatment of pulmonary arterial hypertension (PAH) with oral bosentan hydrate has limitations related to the lack of pulmonary selectivity. In this study, we verified the hypothesis of the feasibility of dry powder inhalation of bose
Autor:
Hyo-Jung Lee, Eun-Soek Park, Yun-Seok Rhee, Jinmann Chon, Hong-Goo Lee, Ju-Young Kim, Dong-Wook Kim, Chun-Woong Park, Yong-Bin Kwon
Publikováno v:
European Journal of Pharmaceutical Sciences. 117:279-289
In this study, we prepared carrier-based formulations for dry powder inhalers by mixing bosentan microparticles with carrier, prepared in three separate types of lactose. Spray-dried, milled and sieved lactose resulted in formulations with various sh