Zobrazeno 1 - 10
of 87
pro vyhledávání: '"YUICHIRO HATANO"'
Autor:
Takamasa Kinoshita, Hiroyuki Tomita, Hideshi Okada, Ayumi Niwa, Fuminori Hyodo, Tomohiro Kanayama, Mikiko Matsuo, Yuko Imaizumi, Takahiro Kuroda, Yuichiro Hatano, Masafumi Miyai, Yusuke Egashira, Yukiko Enomoto, Noriyuki Nakayama, Shigeyuki Sugie, Kazu Matsumoto, Yu Yamaguchi, Masayuki Matsuo, Hideaki Hara, Toru Iwama, Akira Hara
Publikováno v:
Discover Oncology, Vol 12, Iss 1, Pp 1-15 (2021)
Abstract Purpose Heparan sulfate (HS) is one of the factors that has been suggested to be associated with angiogenesis and invasion of glioblastoma (GBM), an aggressive and fast-growing brain tumor. However, it remains unclear how HS of endothelial c
Externí odkaz:
https://doaj.org/article/b5d26bf40ce2496e8e351218cdfaeb3c
Autor:
Mikiko Matsuo, Yuichiro Hatano, Yuko Imaizumi, Takahiro Kuroda, Toshinori Arai, Hiroyuki Tomita, Nobuhisa Matsuhashi, Kazuhiro Yoshida, Akira Hara
Publikováno v:
Diagnostic Pathology, Vol 15, Iss 1, Pp 1-9 (2020)
Abstract Background Intestinal-type adenocarcinoma is widely detected in the gastrointestinal tract, head and neck, lower respiratory and urinary systems. Determining the nature (monoclonal or multicentric) of the intestinal adenocarcinoma is sometim
Externí odkaz:
https://doaj.org/article/60089fd5e14b4c2ea4c7d39ac5010e39
Autor:
Yuichiro Hatano, Maho Tamada, Nami Asano, Yoh Hayasaki, Hiroyuki Tomita, Ken-ichirou Morishige, Akira Hara
Publikováno v:
Diagnostic Pathology, Vol 14, Iss 1, Pp 1-6 (2019)
Abstract Background High-grade serous carcinoma, a representative high-grade ovarian carcinoma, is believed to be closely associated with a TP53 mutation. Recently, this category of ovarian carcinoma has gained increasing attention owing to the recog
Externí odkaz:
https://doaj.org/article/3920bf3770004d15b48ed9d2a8445b0e
Autor:
Hiroyuki Tomita, Kaori Tanaka, Akihiro Hirata, Hideshi Okada, Hisashi Imai, Yohei Shirakami, Kotaro Ohnishi, Shigeyuki Sugie, Hitomi Aoki, Yuichiro Hatano, Kei Noguchi, Tomohiro Kanayama, Ayumi Niwa, Natsuko Suzui, Tatsuhiko Miyazaki, Takuji Tanaka, Haruhiko Akiyama, Masahito Shimizu, Kazuhiro Yoshida, Akira Hara
Publikováno v:
Cell Reports, Vol 34, Iss 8, Pp 108772- (2021)
Summary: Evidence regarding intraductal papillary neoplasm of the bile duct (IPNB) as a type of precancerous lesion of cholangiocarcinoma is limited. Moreover, a reproducible in vivo model is lacking, and IPNB pathogenesis remains unclear. Here, we u
Externí odkaz:
https://doaj.org/article/a450945690e14c17947b9080946d3995
Publikováno v:
Frontiers in Oncology, Vol 10 (2020)
Every cancer carries genomic mutations. Although almost all these mutations arise after fertilization, a minimal count of cancer predisposition mutations are already present at the time of genesis of germ cells. Of the cancer predisposition genes ide
Externí odkaz:
https://doaj.org/article/5629afbc8fe54c7498e5040046b6aada
Autor:
Yuichiro Hatano, Shinya Fukuda, Hiroshi Makino, Hiroyuki Tomita, Ken-ichirou Morishige, Akira Hara
Publikováno v:
Diagnostic Pathology, Vol 13, Iss 1, Pp 1-6 (2018)
Abstract Background Although p53 signature, benign-appearing epithelial cells with p53 diffuse expression, is frequently found in the fallopian tubes, the clinical and pathological significance of this lesion in the case of high-grade serous carcinom
Externí odkaz:
https://doaj.org/article/c41d1aa10ca0425ca1c7b7be23284842
Autor:
Tomohiro Kanayama, Toshiaki Taniguchi, Hiroyuki Tomita, Ayumi Niwa, Kei Noguchi, Mikiko Matsuo, Yuko Imaizumi, Takahiro Kuroda, Yuichiro Hatano, Isao Okazaki, Tatsuo Kato, Akira Hara
Publikováno v:
Diagnostics, Vol 11, Iss 8, p 1463 (2021)
Malignant pleural effusion (MPE) can accompany advanced lung adenocarcinoma. Recent studies suggest that MPE could contain a heterogeneous subpopulation of cells with stem-like properties, such as tumorigenicity and self-renewal, indicating that they
Externí odkaz:
https://doaj.org/article/6f12769239ca49139c72a221f0a98ccb
Autor:
Kei Noguchi, Hiroyuki Tomita, Tomohiro Kanayama, Ayumi Niwa, Yuichiro Hatano, Masato Hoshi, Shigeyuki Sugie, Hideshi Okada, Masayuki Niwa, Akira Hara
Publikováno v:
PLoS ONE, Vol 14, Iss 1, p e0210971 (2019)
Galectin-3 is a β-galactoside-binding lectin which is important in cell proliferation and apoptotic regulation. Recently, serum galectin-3 has been shown to have prognostic value as a biomarker in heart failure. Encephalomyocarditis virus (EMCV) can
Externí odkaz:
https://doaj.org/article/46296ebeafce4e018df5ef3b59ac6a10
Autor:
Tomohiro Kanayama, Hiroyuki Tomita, Nguyen Huy Binh, Yuichiro Hatano, Hitomi Aoki, Hideshi Okada, Akihiro Hirata, Yoshitaka Fujihara, Takahiro Kunisada, Akira Hara
Publikováno v:
PLoS ONE, Vol 14, Iss 8, p e0220818 (2019)
Cytokeratin 19 (KRT19) protein is highly expressed in the epithelium of the gastrointestinal (GI) tract, hepatobiliary tissues, and pancreas of humans and mice. In the present study, we used an improved Cre (iCre) gene to enhance the efficiency of Cr
Externí odkaz:
https://doaj.org/article/6b3424f881814149acfd015aa9740a0a
Autor:
Akira Hara, Masayuki Niwa, Tomohiro Kanayama, Kei Noguchi, Ayumi Niwa, Mikiko Matsuo, Takahiro Kuroda, Yuichiro Hatano, Hideshi Okada, Hiroyuki Tomita
Publikováno v:
Biomolecules, Vol 10, Iss 9, p 1277 (2020)
The use of molecular biomarkers for the early detection of heart disease, before their onset of symptoms, is an attractive novel approach. Ideal molecular biomarkers, those that are both sensitive and specific to heart disease, are likely to provide
Externí odkaz:
https://doaj.org/article/f11540281e3f4f4489e1cdf09de4fb73