Výsledky vyhledávání - "YOSHITAKA TOMIYAMA"

Akademický článek

Pharmacological Profile of KUL-7211, a Selective -Adrenoceptor Agonist, in Isolated Ureteral Smooth Muscle

Autor: Yoshitaka Tomiyama, Makoto Murakami, Kohichi Hayakawa, Katsuyoshi Akiyama, Yoshinobu Yamazaki, Masami Kojima, Nobuo Shibata, Masuo Akahane

Publikováno v: Journal of Pharmacological Sciences, Vol 92, Iss 4, Pp 411-419 (2003)

Since, in the human ureter, both β2- and β3-adrenoceptors mediate adrenergic-stimulation-induced relaxation, selective β2-/β3-adrenoceptor agonists might prove clinically useful for relieving ureteral colic and promoting stone passage. We evaluat

Externí odkaz: https://doaj.org/article/06363c70edbd48bf866b9f1e881497f3

Zobrazit plný text záznamu

Silodosin, an α1A-Adrenoceptor Antagonist, May Ameliorate Ischemia-Induced Bladder Denervation and Detrusor Dysfunction by Improving Bladder Blood Flow

Autor: Kazuyasu Maruyama, Itaru Maruyama, Yoshitaka Tomiyama, Osamu Yamaguchi, Mamoru Kobayashi, Yoshiaki Goi, Masanori Nomiya, Satoshi Tatemichi

Publikováno v: Pharmacology. 97:161-170

Background/Aims: This study was performed to investigate the detailed mechanism underlying the effects of the selective α1A-adrenoceptor antagonist, silodosin, on bladder function in a rat model of atherosclerosis-induced chronic bladder ischemia (C

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::dd1f58b5f28d1c5f99611d7e8bb8343c
https://doi.org/10.1159/000443965

Zobrazit plný text záznamu

Effect of silodosin, a selective α1A-adrenoceptor antagonist, on voiding behavior and bladder blood flow in a rat model of bladder outlet obstruction

Autor: Yoshitaka Tomiyama, Kazuyasu Maruyama, Ayaka Yokoyama, Mamoru Kobayashi, Osamu Yamaguchi, Satoshi Tatemichi, Yoshiaki Goi

Publikováno v: European Journal of Pharmacology. 764:489-496

This study was performed to investigate the effects of silodosin (selective α1A-adrenoceptor antagonist) on bladder blood flow (BBF) and bladder function in a rat model of bladder outlet obstruction (BOO) and to determine the expression of α1-adren

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0339801a47e7e9acaa3eb0b72b3e90e
https://doi.org/10.1016/j.ejphar.2015.07.037

Zobrazit plný text záznamu

Effects of Silodosin, a Selective α 1A -Adrenoceptor Antagonist, on Bladder Blood Flow and Bladder Function in a Rat Model of Atherosclerosis Induced Chronic Bladder Ischemia without Bladder Outlet Obstruction

Autor: Yoshitaka Tomiyama, Osamu Yamaguchi, Yoshiaki Goi, Masanori Nomiya, Koji Sagawa, Ken Aikawa

Publikováno v: Journal of Urology. 190:1116-1122

We investigated the effects of the selective α1A-adrenoceptor antagonist silodosin on bladder blood flow and bladder function in a rat model of atherosclerosis induced chronic bladder ischemia without bladder outlet obstruction.The chronic bladder i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e234f689229589bc4e54538b846afa1
https://doi.org/10.1016/j.juro.2013.03.110

Zobrazit plný text záznamu

Effects of silodosin and tamsulosin on the urethra and cardiovascular system in young and old dogs with benign prostatic hyperplasia

Autor: Yoshinobu Yamazaki, Yoshitaka Tomiyama, Mamoru Kobayashi, Satoshi Tatemichi, Shinya Kobayashi, Yuji Hoyano

Publikováno v: European Journal of Pharmacology. 613:135-140

We examined whether the effects (efficacy on the urethra and hypotension) of silodosin (alpha(1A)-adrenoceptor antagonist) and tamsulosin (alpha(1A+1D)-adrenoceptor antagonist) in dogs with benign prostatic hyperplasia altered with age. We used young

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::416a8d574efd910033895f74ce5c4203
https://doi.org/10.1016/j.ejphar.2009.04.030

Zobrazit plný text záznamu

Gene expressions and mechanical functions of α1-adrenoceptor subtypes in mouse ureter

Autor: Yasue Kubota, Yoshitaka Tomiyama, Yoshinobu Yamazaki, Hiroshi Kusama, Kenjiro Kohri, Yasunori Itoh, Yuji Hoyano, Shinya Kobayashi

Publikováno v: World Journal of Urology. 27:775-780

This study was performed to characterize the α1-adrenoceptor subtypes in mouse ureters as regards gene expressions and contractile functions.The mRNAs for these subtypes were quantified by the real-time quantitative reverse transcription polymerase

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5defb56cbf66e29dbedc6db4d9033ec0
https://doi.org/10.1007/s00345-009-0396-y

Zobrazit plný text záznamu

Effects of four different .ALPHA.1-adrenoceptor antagonists on .ALPHA.-adrenoceptor agonist-induced contractions in isolated mouse and hamster ureters

Autor: Yoshinobu Yamazaki, Hiroshi Kusama, Shinya Kobayashi, Yuji Hoyano, Kazuyasu Maruyama, Yoshitaka Tomiyama

Publikováno v: Journal of Smooth Muscle Research. 45:187-195

To compare the efficacy of the selective alpha(1A)-adrenoceptor antagonist silodosin with those of doxazosin, terazosin, and alfuzosin against alpha-adrenoceptor agonist-induced contractions in mouse and hamster ureters.The four alpha(1)-adrenoceptor

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5efb36e188b903da3a188271b794ca33
https://doi.org/10.1540/jsmr.45.187

Zobrazit plný text záznamu

Silodosin, an α(1A)-Adrenoceptor Antagonist, May Ameliorate Ischemia-Induced Bladder Denervation and Detrusor Dysfunction by Improving Bladder Blood Flow

Autor: Yoshiaki, Goi, Yoshitaka, Tomiyama, Itaru, Maruyama, Satoshi, Tatemichi, Kazuyasu, Maruyama, Mamoru, Kobayashi, Masanori, Nomiya, Osamu, Yamaguchi

Publikováno v: Pharmacology. 97(3-4)

This study was performed to investigate the detailed mechanism underlying the effects of the selective α(1A)-adrenoceptor antagonist, silodosin, on bladder function in a rat model of atherosclerosis-induced chronic bladder ischemia (CBI).The CBI mod

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::fa6453a836db0cc41000c9ef98f79cc7
https://pubmed.ncbi.nlm.nih.gov/26828923

Zobrazit plný text záznamu

Uroselectivity in male dogs of silodosin (KMD-3213), a novel drug for the obstructive component of benign prostatic hyperplasia

Autor: Itaru Maruyama, Yoshinobu Yamazaki, Kumi Kobayashi, Ayaka Maezawa, Mamoru Kobayashi, Satoshi Tatemichi, Yoshitaka Tomiyama, Nobuo Shibata, Shinya Kobayashi

Publikováno v: Neurourology and Urodynamics. 25:792-799

Aims Our main aim was to compare the prostatic selectivity of silodosin with that of other α1-adrenoceptor (AR) antagonists. Methods We examined uroselectivities in two sets of experiments namely, in vitro and in vivo functional studies using male d

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ecf0f405e07185093447147bc710957
https://doi.org/10.1002/nau.20312

Zobrazit plný text záznamu

Effect of Silodosin on Intraurethral Pressure Increase Induced by Hypogastric Nerve Stimulation in Dogs with Benign Prostatic Hyperplasia

Autor: Yoshinobu Yamazaki, Satoshi Tatemichi, Mariko Tadachi, Mamoru Kobayashi, Yoshitaka Tomiyama, Nobuo Shibata, Morimichi Hayashi, Shinya Kobayashi

Publikováno v: YAKUGAKU ZASSHI. 126:225-230

We compared the urethral and cardiovascular eSects of silodosin (selective a1A-adrenoceptor antagonist) ,an ovel medication for benign prostatic hyperplasia (BPH), with those of tamsulosin (selective a1A/a1D-adrenoceptor antagonist) and naftopidil (s

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8049b7b6d18ce6490927db2748597087
https://doi.org/10.1248/yakushi.126.225

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání