Zobrazeno 1 - 10
of 87
pro vyhledávání: '"YOSHITAKA HONDA"'
Autor:
Masahiro Ueki, Shinsuke Hirabayashi, Yoshitaka Honda, Shunichiro Takezaki, Hiroki Ohata, Shimaa Said Mohamed Ali Abdrabou, Saori Sawai, Yukayo Terashita, Yuko Cho, Hideki Muramatsu, Kazushi Izawa, Takahiro Yasumi, Yoshiyuki Takahashi, Masafumi Yamada, Atsushi Manabe
Publikováno v:
Immunological Medicine, Pp 1-8 (2024)
X-linked NF-κB essential modulator (NEMO) deficiency is a primary immunodeficiency characterized by combined immunodeficiency and ectodermal dysplasia. Monocytes from the patients demonstrate a severely impaired response to tissue necrosis factor or
Externí odkaz:
https://doaj.org/article/f35d67264e9c4ebcb28f1c167bfcc122
Autor:
Nobuo Kanazawa, Hiroaki Hemmi, Noriko Kinjo, Hidenori Ohnishi, Jun Hamazaki, Hiroyuki Mishima, Akira Kinoshita, Tsunehiro Mizushima, Satoru Hamada, Kazuya Hamada, Norio Kawamoto, Saori Kadowaki, Yoshitaka Honda, Kazushi Izawa, Ryuta Nishikomori, Miyuki Tsumura, Yusuke Yamashita, Shinobu Tamura, Takashi Orimo, Toshiya Ozasa, Takashi Kato, Izumi Sasaki, Yuri Fukuda-Ohta, Naoko Wakaki-Nishiyama, Yutaka Inaba, Kayo Kunimoto, Satoshi Okada, Takeshi Taketani, Koichi Nakanishi, Shigeo Murata, Koh-ichiro Yoshiura, Tsuneyasu Kaisho
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-11 (2021)
Genetic variants of proteasome subunit genes have been shown to associate with perturbed immune function. Here authors show that a heterozygous missense variant of the immunoproteasome subunit β-type 9 causes an autoinflammatory/immune deficiency sy
Externí odkaz:
https://doaj.org/article/bc153bd94dab48289d8e89f5cfa52002
Autor:
Takayuki Miyamoto, Yoshitaka Honda, Kazushi Izawa, Nobuo Kanazawa, Saori Kadowaki, Hidenori Ohnishi, Masakazu Fujimoto, Naotomo Kambe, Naoya Kase, Takeshi Shiba, Yasuo Nakagishi, Shuji Akizuki, Kosaku Murakami, Masahiro Bamba, Yutaka Nishida, Ayano Inui, Tomoo Fujisawa, Daisuke Nishida, Naomi Iwata, Yoshikazu Otsubo, Shingo Ishimori, Momoko Nishikori, Kiminobu Tanizawa, Tomoyuki Nakamura, Takeshi Ueda, Yoko Ohwada, Yu Tsuyusaki, Masaki Shimizu, Takasuke Ebato, Kousho Iwao, Akiharu Kubo, Toshinao Kawai, Tadashi Matsubayashi, Tatsuhiko Miyazaki, Tomohiro Kanayama, Masahiko Nishitani-Isa, Hiroshi Nihira, Junya Abe, Takayuki Tanaka, Eitaro Hiejima, Satoshi Okada, Osamu Ohara, Megumu K. Saito, Junko Takita, Ryuta Nishikomori, Takahiro Yasumi
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
PurposeUpregulation of type I interferon (IFN) signaling has been increasingly detected in inflammatory diseases. Recently, upregulation of the IFN signature has been suggested as a potential biomarker of IFN-driven inflammatory diseases. Yet, it rem
Externí odkaz:
https://doaj.org/article/5700023cf0774dc68dac5c83825a3a61
Autor:
Mariko Aoki, Kazushi Izawa, Takayuki Tanaka, Yoshitaka Honda, Takeshi Shiba, Yukako Maeda, Takayuki Miyamoto, Keisuke Okamoto, Masahiko Nishitani-Isa, Hiroshi Nihira, Kohsuke Imai, Junko Takita, Ryuta Nishikomori, Eitaro Hiejima, Takahiro Yasumi
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Familial Mediterranean fever (FMF) is a hereditary, autoinflammatory disease that causes recurrent fever, arthritis, and serositis. The diagnosis of FMF is based on the presentation of typical clinical symptoms and the Mediterranean fever gene (MEFV)
Externí odkaz:
https://doaj.org/article/de636ce9fe18427db2a7afcc9eaf72bd
Autor:
Kyoko Yokoi, Sachiko Minamiguchi, Yoshitaka Honda, Mizuho Kobayashi, Satoru Kobayashi, Ryuta Nishikomori
Publikováno v:
Pediatric Rheumatology Online Journal, Vol 19, Iss 1, Pp 1-6 (2021)
Abstract Background Cryopyrin-associated periodic syndrome (CAPS) is a life-long, autoinflammatory disease associated with a gain-of-function mutation in the nucleotide-binding domain, leucine-rich repeat family, pyrin domain containing 3 (NLRP3) gen
Externí odkaz:
https://doaj.org/article/94e3ffc48043492e98243a566a3e764c
Autor:
Fumiko Okazaki, Hiroyuki Wakiguchi, Yuno Korenaga, Tamaki Nakamura, Hiroki Yasudo, Shohei Uchi, Ryoji Yanai, Nobuyuki Asano, Yoshinobu Hoshii, Tsuyoshi Tanabe, Kazushi Izawa, Yoshitaka Honda, Ryuta Nishikomori, Keisuke Uchida, Yoshinobu Eishi, Shouichi Ohga, Shunji Hasegawa
Publikováno v:
Pediatric Rheumatology Online Journal, Vol 19, Iss 1, Pp 1-8 (2021)
Abstract Background Early-onset sarcoidosis (EOS) and Blau syndrome (BS) are systemic inflammatory granulomatous diseases without visible pulmonary involvement, and are distinguishable from their sporadic and familial forms. The diseases are characte
Externí odkaz:
https://doaj.org/article/54f6b49dc8c249f29511c3e28e50503d
Autor:
Takayuki Tanaka, Takeshi Shiba, Yoshitaka Honda, Kazushi Izawa, Takahiro Yasumi, Megumu K. Saito, Ryuta Nishikomori
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
The concept of autoinflammation, first proposed in 1999, refers to a seemingly unprovoked episode of sterile inflammation manifesting as unexplained fever, skin rashes, and arthralgia. Autoinflammatory diseases are caused mainly by hereditary abnorma
Externí odkaz:
https://doaj.org/article/a913a44a94924da998ce46e3eae35517
Autor:
Fumiya Wada, Tadakazu Kondo, Momoko Nakamura, Shunsuke Uno, Masakazu Fujimoto, Takayuki Miyamoto, Yoshitaka Honda, Hirofumi Shibata, Kazushi Izawa, Takahiro Yasumi, Momoko Nishikori, Akifumi Takaori‐Kondo
Publikováno v:
eJHaem, Vol 1, Iss 2, Pp 581-584 (2020)
Externí odkaz:
https://doaj.org/article/9bb532aec1ac4c4893afc8049208f7a8
Autor:
Koji Nakajima, Eitaro Hiejima, Hiroshi Nihira, Kentaro Kato, Yoshitaka Honda, Kazushi Izawa, Naoko Kawabata, Itaru Kato, Eri Ogawa, Mari Sonoda, Tatsuya Okamoto, Hideaki Okajima, Takahiro Yasumi, Junko Takita
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Hepatic manifestations of Epstein-Barr virus (EBV) infection are relatively common, mild, and self-limiting. Although fulminant hepatic failure has been reported in a few cases, the contributing factors are unclear. This report discusses a pediatric
Externí odkaz:
https://doaj.org/article/c6d833a3b68648ffa7d1d6a96bacc5a5
Autor:
Takanori Utsumi, Satoshi Okada, Kazushi Izawa, Yoshitaka Honda, Gen Nishimura, Ryuta Nishikomori, Rika Okano, Masao Kobayashi
Publikováno v:
Frontiers in Endocrinology, Vol 8 (2017)
Spondyloenchondrodysplasia (SPENCD) is an autosomal recessive skeletal dysplasia caused by loss of function mutations in acid phosphatase 5, tartrate resistant (ACP5). Hypomorphic ACP5 mutations impair endochondral bone growth and create an interfero
Externí odkaz:
https://doaj.org/article/32bb9640f9444f6b8509c8e83154b1aa