Zobrazeno 1 - 10
of 244
pro vyhledávání: '"YOSHIO OGURA"'
Autor:
Keiji Shimada, Keizo Kanasaki, Makoto Kato, Yoshio Ogura, Yuta Takagaki, Itaru Monno, Taro Hirai, Munehiro Kitada, Daisuke Koya
Publikováno v:
Journal of Diabetes Investigation, Vol 13, Iss 6, Pp 955-964 (2022)
Abstract Aims/Introduction Sodium–glucose cotransporter 2 inhibitors (SGLT2i) have been shown to display excellent renoprotective effects in diabetic kidney disease with macroalbuminuria/proteinuria. Regarding the renoprotective mechanism of SGLT2i
Externí odkaz:
https://doaj.org/article/0b184aa20b184b93b6ab0ac42f9c8f01
Autor:
Taro Hirai, Munehiro Kitada, Itaru Monno, Erina Oda, Yoshihiro Hayashi, Keiji Shimada, Yuta Takagaki, Yoshio Ogura, Mizue Fujii, Kazunori Konishi, Masaru Sakurai, Atsushi Nakagawa, Daisuke Koya
Publikováno v:
Journal of Diabetes Investigation, Vol 12, Iss 9, Pp 1577-1585 (2021)
Abstract Aims/Introduction The aim of this study was to elucidate whether sodium–glucose cotransporter 2 inhibitors (SGLT2is) treatment has any renoprotective effect for type 2 diabetes mellitus patients with an estimated glomerular filtration rate
Externí odkaz:
https://doaj.org/article/b15014c99b144c01b71d312f5adb526f
Autor:
Taro Hirai, Munehiro Kitada, Yoshihiro Hayashi, Itaru Monno, Yuta Takagaki, Keiji Shimada, Yoshio Ogura, Mizue Fujii, Kazunori Konishi, Atsushi Nakagawa, Daisuke Koya
Publikováno v:
Journal of Diabetes Investigation, Vol 11, Iss 5, Pp 1359-1362 (2020)
Abstract A 58‐year‐old women who was diagnosed with type 2 diabetes 20 years earlier had been treated with antidiabetic medicines since she was aged 40 years. After sodium–glucose cotransporter 2 inhibitors administration, her bodyweight rapidl
Externí odkaz:
https://doaj.org/article/7b3332833085472ea452eefe24ff0be1
Autor:
Munehiro Kitada, Yoshio Ogura, Kyoko Nitta, Mizue Fujii, Keizo Kanasaki, Kazunori Konishi, Yasuo Iida, Atsushi Nakagawa, Daisuke Koya
Publikováno v:
Journal of Diabetes Investigation, Vol 10, Iss 3, Pp 706-713 (2019)
Abstract Aims/Introduction The objective of the present study was to elucidate the effect of switching to teneligliptin from other dipeptidyl peptidase‐4 (DPP‐4) inhibitors on glucose control and renoprotection in type 2 diabetes mellitus patient
Externí odkaz:
https://doaj.org/article/4ed6ef7c1b2545df8e9b706fff5a7172
Publikováno v:
EBioMedicine, Vol 43, Iss , Pp 632-640 (2019)
Lifespan and metabolic health are influenced by dietary nutrients. Recent studies show that a reduced protein intake or low-protein/high-carbohydrate diet plays a critical role in longevity/metabolic health. Additionally, specific amino acids (AAs),
Externí odkaz:
https://doaj.org/article/191377d28ec040dbb99375c5ac14b7f0
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Atherosclerosis is the main cause of mortality in metabolic-related diseases, including cardiovascular disease and type 2 diabetes (T2DM). Atherosclerosis is characterized by lipid accumulation and increased inflammatory cytokines in the vascular wal
Externí odkaz:
https://doaj.org/article/e6c74ba4eaa647ea8a316e4649929c5c
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 8 (2020)
Nutrients are closely involved in the regulation of lifespan and metabolic health. Cellular activities, such as the regulation of metabolism, growth, and aging, are mediated by a network of nutrients and nutrient-sensing pathways. Among the nutrient-
Externí odkaz:
https://doaj.org/article/c9ef6904df4143f0a22fd99b4561c420
Publikováno v:
Frontiers in Physiology, Vol 11 (2020)
The mitochondria are a major source of reactive oxygen species (ROS). Superoxide anion (O2•–) is produced by the process of oxidative phosphorylation associated with glucose, amino acid, and fatty acid metabolism, resulting in the production of a
Externí odkaz:
https://doaj.org/article/d06ebc702f524370bd1d5627ea337715
Autor:
Munehiro Kitada, Yoshio Ogura, Taeko Suzuki, Itaru Monno, Keizo Kanasaki, Ai Watanabe, Daisuke Koya
Publikováno v:
Nutrition & Metabolism, Vol 15, Iss 1, Pp 1-11 (2018)
Abstract Background The objective of this study is to investigate the effects of a low-protein diet (LPD) starting from a young age on diabetic status and renal injury in a rat model of type 2 diabetes and obesity. Methods Diabetic male Wistar fatty
Externí odkaz:
https://doaj.org/article/69d16806d672448ab76e17876a7cb233
Publikováno v:
Antioxidants, Vol 10, Iss 11, p 1754 (2021)
Lifestyle improvement, including through exercise, has been recognized as an important mode of therapy for the suppression of diabetic kidney disease (DKD). However, the detailed molecular mechanisms by which exercise exerts beneficial effects in the
Externí odkaz:
https://doaj.org/article/40d9f28502d04529b2982ebb9938ff98