Zobrazeno 1 - 10
of 35
pro vyhledávání: '"YOSHINORI KASAHARA"'
Autor:
Hideshi Kaneko, Yuki Okada, Daishiro Miura, Takafumi Kimoto, Yoshinori Kasahara, Satsuki Chikura
Publikováno v:
Mutation Research/Genetic Toxicology and Environmental Mutagenesis. 811:21-28
As part of a collaborative study in the Mammalian Mutagenicity Study (MMS) Group of the Japanese Environmental Mutagen Society (JEMS), we investigated the in vivo genotoxicity profile of 1,2-dimethylhydrazine (DMH) using a Pig-a assay in total red bl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e18a8695bd8c0f084f70869712ec8c10
https://doi.org/10.1016/j.mrgentox.2016.02.008
https://doi.org/10.1016/j.mrgentox.2016.02.008
Publikováno v:
The Journal of Veterinary Medical Science
Human immunoglobulin G (IgG) concentrates are immune-modulating, anti-inflammatory plasma-derived products. Clinical studies in recent years have suggested that IgG attenuates neuropathic pain. In this study, effects of sulphonated IgG on the develop
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf2b7f9c90e0cbba3dfcbce4cafc997c
https://doi.org/10.1292/jvms.15-0195
https://doi.org/10.1292/jvms.15-0195
Autor:
Takafumi Kimoto, Yasuhiro Itano, Daishiro Miura, Satsuki Chikura, Xiao-mei Kobayashi, Yoshinori Kasahara, Kumiko Suzuki-Okada
Publikováno v:
Genes and Environment. 36:191-198
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::25a6969cdf585283b477c875c433e956
https://doi.org/10.3123/jemsge.2014.025
https://doi.org/10.3123/jemsge.2014.025
Autor:
Satsuki Chikura, Daishiro Miura, Yuki Okada, Takafumi Kimoto, Hideshi Kaneko, Yoshinori Kasahara
Publikováno v:
Mutation research. Genetic toxicology and environmental mutagenesis. 811
As part of a collaborative study in the Mammalian Mutagenicity Study group of the Japanese Environmental Mutagen Society, we evaluated the in vivo mutagenicity of isopropyl p-toluenesulfonate (IPTS) using a peripheral blood Pig-a assay in rats. Pig-a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b914b3d245a58e4526111dd30092de46
https://pubmed.ncbi.nlm.nih.gov/27931803
https://pubmed.ncbi.nlm.nih.gov/27931803
Autor:
Robert H. Heflich, Kumiko Suzuki, Takafumi Kimoto, Daishiro Miura, Xiao mei Kobayashi, Vasily N. Dobrovolsky, Yoshinori Kasahara
Publikováno v:
Mutation Research/Genetic Toxicology and Environmental Mutagenesis. 723:36-42
Our previous rat studies indicate that the endogenous Pig-a gene is a promising reporter of in vivo mutation and potentially useful as the basis for an in vivo genotoxicity assay. The function of the Pig-a protein in the synthesis of glycosylphosphat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32006ed96c99bdf406d719b29e62a1cb
https://doi.org/10.1016/j.mrgentox.2011.03.016
https://doi.org/10.1016/j.mrgentox.2011.03.016
Autor:
Yoshinori Kasahara, Vasily N. Dobrovolsky, Daishiro Miura, Takafumi Kimoto, Robert H. Heflich
Publikováno v:
Mutation Research/Genetic Toxicology and Environmental Mutagenesis. 677:86-92
We previously reported the development of an in vivo gene mutation assay using the phosphatidylinositol glycan complementation group A gene (Pig-A) as an endogenous reporter. The assay quantifies mutation in rat peripheral red blood cells (RBCs) by f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::657a9ebf78814e9305b41ae7bc10be0a
https://doi.org/10.1016/j.mrgentox.2009.05.014
https://doi.org/10.1016/j.mrgentox.2009.05.014
Autor:
Satoko Kakiuchi, Shiro Kondo, Yoshinori Kasahara, Yoshihide Satomi, Mitsuru Kobayshi, Daishiro Miura
Publikováno v:
The Journal of Toxicological Sciences. 31:111-122
We performed a flow cytometric (FCM) analysis of the maturity of reticulocytes using peripheral blood obtained from rats administered 5-fluorouracil (5-FU) at 10, 50 and 100 mg/kg or acethylphenyl hydrazine (APHZ) at 1 and 3 mg/kg to clarify whether
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c1a53389aa3c968f4309b0b498b059b
https://doi.org/10.2131/jts.31.111
https://doi.org/10.2131/jts.31.111
Autor:
Satoru Itoh, Hiroyasu Shimada, Eiji Yamamura, Yukimi Takahashi, Yoshiteru Miyauchi, Miki Miura, Miho Suga, Yoshinori Kasahara, Haruyoshi Hirono, Toshiaki Itoh
Publikováno v:
Mutation Research/Genetic Toxicology and Environmental Mutagenesis. 444:309-319
The mutagenic and clastogenic effects of N -nitrosodi- n -propylamine (NDPA) in lacZ transgenic mice (Muta™Mouse) were investigated as a part of the second collaborative study of the transgenic mouse mutation assay by a subgroup of the Mammalian Mu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::70e9850eb0e1aa113fc2198e2e4bc485
https://doi.org/10.1016/s1383-5718(99)00062-5
https://doi.org/10.1016/s1383-5718(99)00062-5
Publikováno v:
JOURNAL OF PAVEMENT ENGINEERING, JSCE. 2:45-52
This paper covers the basic study on ultra-thin white topping that is also been developed in European countries and U. S. A. The aims are to find out its applicability through making mini model experiments, research on the interface shear stress unde
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d5aa8f772f9c366f22fbe2b3782670f0
https://doi.org/10.2208/journalpe.2.45
https://doi.org/10.2208/journalpe.2.45
Autor:
Xiao-mei Kobayashi, Yoshinori Kasahara, Daishiro Miura, Satsuki Chikura, Yasuhiro Itano, Kumiko Suzuki-Okada, Takafumi Kimoto
Publikováno v:
The Journal of toxicological sciences. 37(5)
The Pig-a gene mutation assay using perpherial blood erythrocytes is being investigated as a screening tool for assessing mutagenicity in vivo. In this study, we evaluated two distinct approaches for performing the Pig-a assay in rats. We used antibo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f4bfcb2a96dc31640a33d47f8d08570
https://pubmed.ncbi.nlm.nih.gov/23038003
https://pubmed.ncbi.nlm.nih.gov/23038003